Medical News

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• MM-WES: Genotyping reduces warfarin-associated hospitalizations
• Asthma linked to low vitamin D levels in young African Americans
• Type 2 diabetes linked to reduced lung function in morbidly obese women
• VOC breath profiling may help diagnose COPD
• Striatal dopamine hyperactivity found in schizophrenia
• Substance use triggers illness switch in depressed bipolar patients
• PASSION: Older drug-eluting stents not superior to bare-metal design
• Treatment disparities might explain increased mortality in women post-MI
• Long-term side effects similar after high- and low-dose prostate RT
• Case managers reduce diagnostic delay following an abnormal mammogram
• Lipid levels affect cognitive function more in early than late old age
• Lipid ratios may be ‘simple, integrated’ CVD risk markers
• Salsalate improves glycemic control in Type 2 diabetics
• Type 2 diabetes impairs pulmonary function in morbidly obese women
• DOSE: High-dose loop diuretics might benefit acute heart failure patients
• ASPIRE: Direct renin inhibitor does not help prevent LV remodeling post-MI

MM-WES: Genotyping reduces warfarin-associated hospitalizations Posted: 17 Mar 2010 05:00 PM PDT Genotyping patients on warfarin anticoagulation therapy reduces hospitalizations for all causes by nearly 30%, reported investigators from the Medco-Mayo Warfarin Effectiveness Study on the final day of the 59th annual Scientific Sessions of the American College of Cardiology, in Atlanta, Georgia, USA.

Asthma linked to low vitamin D levels in young African Americans Posted: 17 Mar 2010 05:00 PM PDT Young African Americans with asthma are significantly more likely to have low levels of vitamin D than their counterparts without the respiratory condition, US researchers have found.

Type 2 diabetes linked to reduced lung function in morbidly obese women Posted: 17 Mar 2010 05:00 PM PDT The presence of Type 2 diabetes is associated with significantly reduced lung function in morbidly obese women, research shows.

VOC breath profiling may help diagnose COPD Posted: 17 Mar 2010 05:00 PM PDT The presence of six volatile organic compounds in breath can accurately distinguish patients with chronic obstructive disease from those without the condition, research shows.

Striatal dopamine hyperactivity found in schizophrenia Posted: 17 Mar 2010 05:00 PM PDT Patients with schizophrenia display hyperactive dopamine transmission at synapses within the associative striatum, results of an imaging study show.

Substance use triggers illness switch in depressed bipolar patients Posted: 17 Mar 2010 05:00 PM PDT Bipolar disorder patients experiencing an episode of depression are more likely to switch into manic, mixed, or hypomanic states before recovery if they have a history of substance or alcohol use disorder, research shows.

PASSION: Older drug-eluting stents not superior to bare-metal design Posted: 17 Mar 2010 05:00 PM PDT First-generation paclitaxel-eluting stents are no better than bare-metal stents at reducing the occurrence of major adverse cardiac events after 5 years, reported investigators from the PASSION trial.

Treatment disparities might explain increased mortality in women post-MI Posted: 17 Mar 2010 05:00 PM PDT A lower use of invasive procedures and reperfusion strategy might explain why women fare worse than men after acute myocardial infarction, a propensity analysis shows.

Long-term side effects similar after high- and low-dose prostate RT Posted: 16 Mar 2010 05:00 PM PDT A 79.2-Gy dose of radiotherapy to the prostate does not worsen long-term urinary, bowel, and sexual function compared with a dose of 70.2 Gy, according to a patient survey.

Case managers reduce diagnostic delay following an abnormal mammogram Posted: 16 Mar 2010 05:00 PM PDT Implementing case management to a national breast cancer screening program reduces the time to diagnosis among low-income women with an abnormal mammogram, US research shows

Lipid levels affect cognitive function more in early than late old age Posted: 16 Mar 2010 05:00 PM PDT High lipid levels are a greater risk factor for cognitive dysfunction before the age of 65 years than afterwards, report researchers.

Lipid ratios may be ‘simple, integrated’ CVD risk markers Posted: 16 Mar 2010 05:00 PM PDT Three lipid ratios are strongly and consistently associated with the metabolic syndrome, insulin resistance, and adiponectin, a Korean study suggests.

Salsalate improves glycemic control in Type 2 diabetics Posted: 16 Mar 2010 05:00 PM PDT Salsalate, a nonacetylated prodrug of salicylate, similar to aspirin, is effective for improving glycemic control in Type 2 diabetics, report US researchers.

Type 2 diabetes impairs pulmonary function in morbidly obese women Posted: 16 Mar 2010 05:00 PM PDT The presence of Type 2 diabetes significantly impairs pulmonary function in morbidly obese women, show study results.

DOSE: High-dose loop diuretics might benefit acute heart failure patients Posted: 16 Mar 2010 05:00 PM PDT Continuous 24-hour infusion of loop diuretics was no better at reducing symptoms of acute decompensated heart failure over 72 hours than was bolus dosing every 12 hours, reported investigators of the DOSE study.

ASPIRE: Direct renin inhibitor does not help prevent LV remodeling post-MI Posted: 16 Mar 2010 05:00 PM PDT The addition of the direct rennin inhibitor aliskiren to standard optimal treatment does not reduce the risk for left ventricular remodeling in high-risk post myocardial infarction patients, findings from the ASPIRE study show.

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