Medical News

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• Surgical specialty impacts CEA outcomes
• Temazepam ‘does not reduce lung function in COPD patients’
• Peanut allergy linked to increased asthma morbidity in children
• Early-life chlamydial lung infection may increase future asthma severity
• Stepwise model predicts psychosis risk in vulnerable adolescents
• Alcohol binge drinking linked to increased hypomania risk
• Acute bacterial gastroenteritis linked to IBS in children
• PLATO: Ticagrelor lowers total and CV mortality vs clopidogrel in CABG patients
• Comparable patency achieved with radial artery and saphenous vein grafts
• Genetic risk for aneurysms increased by smoking
• Patients with poorly differentiated prostate tumors benefit most from curative treatment
• Pre-op serum testosterone correlated with sexual, urinary function in RP patients
• Patients with poorly differentiated prostate tumors benefit most from curative treatment
• Lapatinib plus capecitabine feasible for advanced HER2-positive breast cancer
• Pre-op serum testosterone correlated with sexual, urinary function in RP patients
• Rosuvastatin cuts LDL-C in children with familial hypercholesterolemia
• Pitavastatin treatment reduces marker of oxidative stress
• Waist-to-thigh ratio predicts diabetes better in men than women
• Moderate soft drink consumption may increase risk for Type 2 diabetes in Asians
• Lapatinib plus capecitabine feasible for advanced HER2-positive breast cancer
• Long-term side effects similar after high- and low-dose prostate RT
• Case managers reduce diagnostic delay following an abnormal mammogram
• Great demand for new markers to improve prostate cancer diagnosis
• Better communication may improve understanding of genomic test results
• IMRT versus RapidArc – superiority depends on PTV
• External sphincter temperature predicts voiding function after cryoablation
• Early results suggest trastuzumab may improve radiotherapy efficacy

Surgical specialty impacts CEA outcomes Posted: 18 Mar 2010 05:00 PM PDT Patients undergoing carotid endarterectomy (CEA) have better long-term outcomes if their operation is performed by a vascular specialist, research suggests.

Temazepam ‘does not reduce lung function in COPD patients’ Posted: 18 Mar 2010 05:00 PM PDT Results from a preliminary Dutch study suggest that the benzodiazepine temazepam does not reduce circadian respiratory function in patients with severe chronic obstructive pulmonary disease who suffer from insomnia.

Peanut allergy linked to increased asthma morbidity in children Posted: 18 Mar 2010 05:00 PM PDT The presence of peanut allergy is associated with a greater number of hospitalizations and increased systemic steroid use in children with asthma, research shows.

Early-life chlamydial lung infection may increase future asthma severity Posted: 18 Mar 2010 05:00 PM PDT Chlamydial lung infections in early life may influence immune responses and respiratory function, and increase the severity of asthma in later life, suggest results from a study in mice.

Stepwise model predicts psychosis risk in vulnerable adolescents Posted: 18 Mar 2010 05:00 PM PDT Young adults and adolescents who seek help for prodromal psychotic symptoms should undergo a two-step risk assessment to determine their likelihood for developing full-blown psychosis, say researchers.

Alcohol binge drinking linked to increased hypomania risk Posted: 18 Mar 2010 05:00 PM PDT Young men who report an unstable pattern of alcohol consumption including binge drinking have an elevated risk for experiencing hypomania, study results show.

Acute bacterial gastroenteritis linked to IBS in children Posted: 18 Mar 2010 05:00 PM PDT A Canadian outbreak of acute bacterial gastroenteritis suggests the illness is associated with irritable bowel syndrome in children as well as adults.

PLATO: Ticagrelor lowers total and CV mortality vs clopidogrel in CABG patients Posted: 18 Mar 2010 05:00 PM PDT Ticagrelor was associated with significantly lower total and cardiovascular mortality when compared with clopidogrel in acute coronary syndrome patients undergoing coronary artery bypass graft surgery, without any difference in the risk of bleeding related to surgery, latest PLATO subanalysis findings show.

Comparable patency achieved with radial artery and saphenous vein grafts Posted: 18 Mar 2010 05:00 PM PDT Study findings indicate that radial artery vein grafts provide comparable patency to saphenous vein grafts at 1 year after coronary artery bypass graft surgery.

Genetic risk for aneurysms increased by smoking Posted: 17 Mar 2010 05:00 PM PDT People with genetic variants that increase their risk for developing intracranial aneurysms greatly exacerbate their risk if they smoke, shows research.

Patients with poorly differentiated prostate tumors benefit most from curative treatment Posted: 17 Mar 2010 05:00 PM PDT Men with poorly differentiated prostate tumors benefit more from curative treatment, such as radiotherapy or surgery, than men with well-differentiated tumors, report researchers.

Pre-op serum testosterone correlated with sexual, urinary function in RP patients Posted: 17 Mar 2010 05:00 PM PDT Men with low serum testosterone levels before radical prostatectomy have significantly worse erectile function than those with normal levels, show study findings.

Patients with poorly differentiated prostate tumors benefit most from curative treatment Posted: 17 Mar 2010 05:00 PM PDT Men with poorly differentiated prostate tumors benefit more from curative treatment, such as radiotherapy or surgery, than men with well-differentiated tumors, report researchers.

Lapatinib plus capecitabine feasible for advanced HER2-positive breast cancer Posted: 17 Mar 2010 05:00 PM PDT Lapatinib combined with capecitabine is an active treatment option for women with advanced human epidermal growth factor receptor (HER)2-positive breast cancer, including those with progressive central nervous system disease, UK researchers report.

Pre-op serum testosterone correlated with sexual, urinary function in RP patients Posted: 17 Mar 2010 05:00 PM PDT Men with low serum testosterone levels before radical prostatectomy have significantly worse erectile function than those with normal levels, show study findings.

Rosuvastatin cuts LDL-C in children with familial hypercholesterolemia Posted: 17 Mar 2010 05:00 PM PDT Rosuvastatin therapy significantly reduces levels of low-density lipoprotein cholesterol and is well-tolerated in adolescents with familial hypercholesterolemia, a randomized placebo-controlled trial has found.

Pitavastatin treatment reduces marker of oxidative stress Posted: 17 Mar 2010 05:00 PM PDT Pitavastatin treatment brings about beneficial changes in serum markers of oxidative stress, a study in people with hypercholesterolemia has found.

Waist-to-thigh ratio predicts diabetes better in men than women Posted: 17 Mar 2010 05:00 PM PDT Study results show that the waist-to-thigh ratio is more strongly associated with diabetes than four other anthropomorphic measures in men, but is only equally associated with diabetes with the same measures in women.

Moderate soft drink consumption may increase risk for Type 2 diabetes in Asians Posted: 17 Mar 2010 05:00 PM PDT Consumption of two or more soft drinks or portions of juice per week is associated with increased risk for Type 2 diabetes in a Chinese population from Singapore, show study results.

Lapatinib plus capecitabine feasible for advanced HER2-positive breast cancer Posted: 17 Mar 2010 05:00 PM PDT Lapatinib combined with capecitabine is an active treatment option for women with advanced human epidermal growth factor receptor (HER)2-positive breast cancer, including those with progressive central nervous system disease, UK researchers report.

Long-term side effects similar after high- and low-dose prostate RT Posted: 16 Mar 2010 05:00 PM PDT A 79.2-Gy dose of radiotherapy to the prostate does not worsen long-term urinary, bowel, and sexual function compared with a dose of 70.2 Gy, according to a patient survey.

Case managers reduce diagnostic delay following an abnormal mammogram Posted: 16 Mar 2010 05:00 PM PDT Implementing case management to a national breast cancer screening program reduces the time to diagnosis among low-income women with an abnormal mammogram, US research shows

Great demand for new markers to improve prostate cancer diagnosis Posted: 15 Mar 2010 05:00 PM PDT There is a great demand for new markers to improve prostate cancer diagnosis and prevent unnecessary prostate biopsies, especially in men with a serum prostate-specific antigen of 4–10 ng/ml, say researchers.

Better communication may improve understanding of genomic test results Posted: 15 Mar 2010 05:00 PM PDT US researchers report that a significant number of women do not fully understand discussions about their genomic-based recurrence risk for breast cancer.

IMRT versus RapidArc – superiority depends on PTV Posted: 14 Mar 2010 05:00 PM PDT For men undergoing radiotherapy of the prostate, conventional intensity-modulated radiotherapy performs better than RapidArc in dose sparing of the bladder, rectum, and small bowel for planning target volumes that include the prostate, seminal vesicles, and lymph nodes, researchers report.

External sphincter temperature predicts voiding function after cryoablation Posted: 14 Mar 2010 05:00 PM PDT Patients who have an external sphincter temperature of 23°C or less during cryoablation are significantly more likely to experience urgency and/or frequency of urinary retention after cryoablation, study findings show.

Early results suggest trastuzumab may improve radiotherapy efficacy Posted: 14 Mar 2010 05:00 PM PDT A small trial of women with locally advanced breast cancer has revealed that trastuzumab may improve the efficacy of radiotherapy without increasing operative morbidity or radiotherapy-related toxicity.

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