| Hospital shift patterns influence stroke fatality Posted: 29 Jul 2010 05:00 PM PDT Stroke patients are more likely to die within 7 days if they are admitted to hospital at night or during the weekend, say Dutch researchers who also report a protective effect of the afternoon-to-evening shift handover.  |
| Ventilatory problems play progressive role in activity limitations in COPD Posted: 29 Jul 2010 05:00 PM PDT Results from a Dutch study show that ventilatory problems play an important and progressive role in limitations to activities of daily life in patients with chronic obstructive pulmonary disease.  |
| Emphysema associated with activity limitations in COPD Posted: 29 Jul 2010 05:00 PM PDT Results from a US study indicate that the extent of emphysema, but not airways disease, is associated with activity limitations in patients with chronic obstructive pulmonary disease.  |
| Diet pattern in pregnancy not linked to recurrent wheeze in children Posted: 29 Jul 2010 05:00 PM PDT A woman's dietary pattern during pregnancy does not influence her child's risk for suffering recurrent wheeze in early life, US study results suggest.  |
| Disorganization should be distinguished from reality distortion in schizophrenia Posted: 29 Jul 2010 05:00 PM PDT Disorganization may represent a separate set of positive symptoms from reality distortion that is independently linked to neurocognition in schizophrenia patients, scientists suggest.  |
| Sustained attention deficit a potential endophenotye for bipolar disorder Posted: 29 Jul 2010 05:00 PM PDT Researchers suggest that sustained attention deficit is an endophenotype for bipolar disorder that is maintained during asymptomatic states.  |
| Pre-treatment genitourinary symptoms can improve after EBRT to the prostate Posted: 29 Jul 2010 05:00 PM PDT Prostate cancer patients with pretreatment obstructive urinary symptoms can experience improvement in their urinary function after external beam radiotherapy, without increasing their risk for severe genitourinary toxicity, report US researchers.  |
| Rare genetic variants contribute to hypertriglyceridemia Posted: 29 Jul 2010 05:00 PM PDT Rare mutations in four genes contribute considerably to the unexplained genetic component of hypertriglyceridemia, suggests a study published in the journal Nature Genetics.  |
| Statins may have dual action on vulnerable plaque Posted: 29 Jul 2010 05:00 PM PDT Statin therapy may stabilize vulnerable atherosclerotic plaque by decreasing total atheroma volume and increasing fibrous cap thickness, a study suggests.  |
| Esophageal cancer risk increased in achalasia patients Posted: 29 Jul 2010 05:00 PM PDT People with achalasia, a rare esophageal motility disorder, are at increased risk for esophageal cancer compared with the general population, study findings show.  |
| Exenatide treatment improves adiponectin and CRP levels Posted: 29 Jul 2010 05:00 PM PDT Treatment with the oral hypoglycemic drug exenatide has beneficial effects on adiponectin and C-reactive protein levels, suggest study findings published in the journal Diabetes Care. |
| High methylglyoxal linked to adverse CV profile in Type 2 diabetics Posted: 29 Jul 2010 05:00 PM PDT Elevated methylglyoxal levels predict increased carotid intima-media thickness and increased blood pressure in patients with Type 2 diabetes, report researchers.  |
| Distal embolization influences outcome in STEMI patients Posted: 28 Jul 2010 05:00 PM PDT Distal embolization is associated with impaired myocardial perfusion and survival in patients treated with primary angioplasty and glycoprotein IIb–IIIa inhibitors for ST segment elevation myocardial infarction, study findings indicate.  |
| Carotid revascularization rates vary widely across the USA Posted: 28 Jul 2010 05:00 PM PDT Use of carotid revascularization techniques vary widely among different US hospital referral regions, researchers report in the Archives of Internal Medicine.  |
| Elastography allows prostate cancer detection in fewer cores than systemic biopsy Posted: 28 Jul 2010 05:00 PM PDT Real-time elastography-targeted prostate biopsy can detect the presence of prostate cancer using fewer cores than are needed with systematic biopsy in men with a prostate-specific antigen level between 1.25 and 4.00 ng/ml, say researchers.  |
| Time to PSA detection after surgery predicts prostate cancer recurrence Posted: 28 Jul 2010 05:00 PM PDT The risk for possible disease recurrence indicated by biochemical failure after surgery for prostate cancer decreases the longer it takes to detect a patient's prostate-specific antigen level, study findings show.  |
| Elastography allows prostate cancer detection in fewer cores than systemic biopsy Posted: 28 Jul 2010 05:00 PM PDT Real-time elastography-targeted prostate biopsy can detect the presence of prostate cancer using fewer cores than are needed with systematic biopsy in men with a prostate-specific antigen level between 1.25 and 4.00 ng/ml, say researchers.  |
| Time to PSA detection after surgery predicts prostate cancer recurrence Posted: 28 Jul 2010 05:00 PM PDT The risk for possible disease recurrence indicated by biochemical failure after surgery for prostate cancer decreases the longer it takes to detect a patient's prostate-specific antigen level, study findings show.  |
| Combined chemotherapy regimens effective for metastatic breast cancer Posted: 28 Jul 2010 05:00 PM PDT Epirubicin plus cyclophosphamide and epirubicin plus docetaxel are highly effective combinations for first-line chemotherapy of metastatic breast cancer, research shows.  |
| Tea drinking could prevent coronary artery calcification Posted: 28 Jul 2010 05:00 PM PDT Drinking tea may help prevent the development and progression of coronary artery calcification, researchers report.  |
| <i>FADS1</i> variant may influence health benefits of specific PUFAs Posted: 28 Jul 2010 05:00 PM PDT Genetic variation in the FADS1 gene seems to interact with dietary intake of polyunsaturated fatty acids to influence plasma cholesterol levels, a Dutch team has found.  |
| High vitamin K intake associated with reduced risk for Type 2 diabetes Posted: 28 Jul 2010 05:00 PM PDT A high intake of phylloquinone and menaquinone is associated with a reduced risk for Type 2 diabetes, show results published in the journal Diabetes Care.  |
| Elevated pulse pressure may predict future CAD in diabetics Posted: 28 Jul 2010 05:00 PM PDT Israeli researchers suggest that an elevated pulse pressure may indicate the presence of pre-clinical coronary artery disease in patients with diabetes.  |
| AF increases mortality risk in HF patients with underlying IHD Posted: 28 Jul 2010 05:00 PM PDT Presence of atrial fibrillation is only associated with increased risk for death in heart failure patients who have underlying ischemic heart disease , report researchers.  |
| Novel 3D echo technique improves congenital heart defect identification Posted: 28 Jul 2010 05:00 PM PDT A leading cardiologist from Southampton General Hospital, UK, has developed a novel technique to improve the accuracy of cardiac visualization during three-dimensional echocardiography.  |
| Combined chemotherapy regimens effective for metastatic breast cancer Posted: 28 Jul 2010 05:00 PM PDT Epirubicin plus cyclophosphamide and epirubicin plus docetaxel are highly effective combinations for first-line chemotherapy of metastatic breast cancer, research shows.  |
| Brachytherapy achieves excellent results in ‘young’ prostate cancer patients Posted: 27 Jul 2010 05:00 PM PDT Men with prostate cancer who are aged 60 years or younger can achieve excellent 5- and 8-year biochemical control rates after treatment with brachytherapy, report US researchers.  |
| Polygenic risk score predictive of breast cancer subtype Posted: 27 Jul 2010 05:00 PM PDT A study of common genetic variants for breast cancer has revealed that a polygenic risk score is substantially more predictive of estrogen receptor-positive than of ER-negative breast cancer.  |
| ADT for prostate cancer does not negatively impact cognition Posted: 26 Jul 2010 05:00 PM PDT Prostate cancer patients treated with androgen deprivation therapy do not experience a worsening of cognition after treatment, show the results of a US study.  |
| Majority of low-risk prostate cancer is treated aggressively Posted: 26 Jul 2010 05:00 PM PDT The majority of men with low-risk prostate cancer are nonetheless treated aggressively, say US researchers who analyzed risk profiles and factors associated with treatment using the Surveillance, Epidemiology, and End Results database.  |
| Multiple factors affect body image in long-term breast cancer survivors Posted: 26 Jul 2010 05:00 PM PDT Poor body image in long-term breast cancer survivors is associated with the type of surgery received and local body changes after treatment, as well as mental distress, reduced health, and impaired quality of life, researchers report.  |
| PSA velocity is not a good indicator of prostate re-biopsy outcome Posted: 25 Jul 2010 05:00 PM PDT Prostate-specific antigen velocity is not a useful predictor of a positive outcome at repeat prostate biopsy after an initial negative outcome, report researchers.  |
| Citalopram effective in managing hot flashes Posted: 25 Jul 2010 05:00 PM PDT Good efficacy and minimal toxicity make citalopram a candidate for managing hot flashes associated with tamoxifen use, according to US researchers.  |
