Medical News

---

• <i>CRP</i> genotype does not increase VTE risk
• Presumed perinatal stroke subtypes defined
• Increased COPD severity linked to decreasing heart size
• Children with asthma and AR have altered oxidative state
• Interferon may benefit asthma patients
• Abnormal oscillatory activity in schizophrenia clarified
• Ecologically valid cognitive tests effective in euthymic bipolar patients
• Traumatic experiences linked to psoriasis onset
• IMP3 ‘not prognostic for prostate cancer, despite raised expression’
• ANNs may aid discrimination between benign and malignant breast disease
• IMP3 ‘not prognostic for prostate cancer, despite raised expression’
• Childhood vascular risk factors predict later atherosclerosis
• Biliary secretion not essential for cholesterol expulsion
• <i>H. pylori</i> promotes invasive gene expression in gastric cancer
• Colorectal cancer screening test more accurate in winter than summer
• Critical illness hyperglycemia ‘a risk factor for future diabetes’
• Type 2 diabetes ‘reduces life expectancy’
• Raising awareness fails to speed women’s presentation for MI
• Calcium channel blockers linked to increased heart failure risk
• ANNs may aid discrimination between benign and malignant breast disease
• Thyroid autoantibodies may affect warfarin stability
• AAN recommends MRI for stroke diagnosis
• Genetic polymorphisms improve recurrence prediction after prostate surgery
• Research sheds light on anti-prostate cancer effects of broccoli
• Genetic polymorphisms improve recurrence prediction after prostate surgery
• Research sheds light on anti-prostate cancer effects of broccoli
• Reduced E-cadherin predicts poor prognosis in triple-negative breast cancer
• Missing link in triglyceride metabolism identified
• <i>ABCA1</i> variant affects CHD risk, statin response in FH patients
• Active sun exposure reduces Type 2 diabetes risk in women
• Rising BMI responsible for large proportion Type 2 diabetes increase in men
• Radial approach improves PCI outcomes
• Is screening for subclinical atherosclerosis worthwhile?
• Reduced E-cadherin predicts poor prognosis in triple-negative breast cancer
• AUR after prostate brachytherapy linked to treatment trauma, not dose
• Sunitinib plus paclitaxel well tolerated in advanced breast cancer
• Brachytherapy more efficient than EBRT for prostate cancer
• Lymph node metastasis, HER2-status predict recurrence after breast cancer response
• Clinical prostate cancer stage ‘does not predict recurrence risk’
• Quality of life worsening by IMRT for prostate cancer only temporary
• PET/CT superior to bone scintigraphy for detecting metastatic breast cancer

<i>CRP</i> genotype does not increase VTE risk Posted: 15 Jul 2010 05:00 PM PDT Danish researchers have confirmed the link between elevated C-reactive protein and increased risk for venous thromboembolism, but cast doubt on whether the association is causal.

Presumed perinatal stroke subtypes defined Posted: 15 Jul 2010 05:00 PM PDT Arterial presumed perinatal ischemic stroke and periventricular venous infarction are associated with distinct risk factor profiles, research suggests.

Increased COPD severity linked to decreasing heart size Posted: 15 Jul 2010 05:00 PM PDT Study findings show that increasing severity of chronic obstructive pulmonary disease is associated with a decreasing heart size.

Children with asthma and AR have altered oxidative state Posted: 15 Jul 2010 05:00 PM PDT Children with asthma and allergic rhinitis have an altered oxidative state relative to children without these conditions, research suggests.

Interferon may benefit asthma patients Posted: 15 Jul 2010 05:00 PM PDT Interferon, a cytokine used to treat diseases such as multiple sclerosis, hepatitis C, and a variety of cancers, may also benefit asthma patients by preventing the production of T helper 2 cells, researchers have found.

Abnormal oscillatory activity in schizophrenia clarified Posted: 15 Jul 2010 05:00 PM PDT Researchers suggest that abnormal brain electrical activity in schizophrenia patients during information processing may not only be phase-locked to stimulus onset, but also be induced by the stimulus in a variable time relationship.

Ecologically valid cognitive tests effective in euthymic bipolar patients Posted: 15 Jul 2010 05:00 PM PDT Ecologically valid tests of cognitive function appear to be sensitive for detecting cognitive impairment in euthymic bipolar disorder patients, research shows.

Traumatic experiences linked to psoriasis onset Posted: 15 Jul 2010 05:00 PM PDT Research suggests that the likelihood of developing psoriasis is increased in people who have experienced negative traumatic experiences during childhood or adulthood.

IMP3 ‘not prognostic for prostate cancer, despite raised expression’ Posted: 15 Jul 2010 05:00 PM PDT Insulin-like growth factor II mRNA binding protein 3 (IMP3) is significantly overexpressed in prostate cancer, although it does not appear to have any prognostic importance, say scientists.

ANNs may aid discrimination between benign and malignant breast disease Posted: 15 Jul 2010 05:00 PM PDT An artificial neural network model developed by US scientists effectively discriminates malignant abnormalities from benign ones, and accurately predicts the risk for breast cancer for individual patients, they say.

IMP3 ‘not prognostic for prostate cancer, despite raised expression’ Posted: 15 Jul 2010 05:00 PM PDT Insulin-like growth factor II mRNA binding protein 3 (IMP3) is significantly overexpressed in prostate cancer, although it does not appear to have any prognostic importance, say scientists.

Childhood vascular risk factors predict later atherosclerosis Posted: 15 Jul 2010 05:00 PM PDT The number of vascular risk factors seen in children predicts change in carotid intima-media thickness over 6 years in adulthood, show data from the Cardiovascular Risk in Young Finns study.

Biliary secretion not essential for cholesterol expulsion Posted: 15 Jul 2010 05:00 PM PDT Reverse cholesterol transport and cholesterol loss through the feces continue in mice genetically and surgically unable to secrete it in bile, supporting the existence of a nonbiliary secretion pathway, say researchers.

<i>H. pylori</i> promotes invasive gene expression in gastric cancer Posted: 15 Jul 2010 05:00 PM PDT Helicobacter pylori infection promotes invasive gene expression in a gastric cancer model – a process that is mediated by matrix metalloproteinase-7, heparin-binding epidermal growth factor, and gastrin, study results show.

Colorectal cancer screening test more accurate in winter than summer Posted: 15 Jul 2010 05:00 PM PDT Study results show that the immunochemical fecal occult blood test for detecting colorectal cancer is approximately 13% less accurate in the summer than in the winter.

Critical illness hyperglycemia ‘a risk factor for future diabetes’ Posted: 15 Jul 2010 05:00 PM PDT People with hyperglycemia during critical illness are at increased risk for developing glucose intolerance and diabetes in the future, research suggests.

Type 2 diabetes ‘reduces life expectancy’ Posted: 15 Jul 2010 05:00 PM PDT Both all-cause and cardiovascular mortality are substantially increased in people with Type 2 diabetes compared with nondiabetics, UK researchers have shown.

Raising awareness fails to speed women’s presentation for MI Posted: 15 Jul 2010 05:00 PM PDT Time from symptom onset to hospital presentation for myocardial infarction is longer among women than men, and so far cardiovascular disease risk awareness campaigns aimed at women have not reduced this delay, suggest US researchers.

Calcium channel blockers linked to increased heart failure risk Posted: 15 Jul 2010 05:00 PM PDT Calcium channel blockers may increase the risk for heart failure among patients with hypertension, Canadian researchers report.

ANNs may aid discrimination between benign and malignant breast disease Posted: 15 Jul 2010 05:00 PM PDT An artificial neural network model developed by US scientists effectively discriminates malignant abnormalities from benign ones, and accurately predicts the risk for breast cancer for individual patients, they say.

Thyroid autoantibodies may affect warfarin stability Posted: 14 Jul 2010 05:00 PM PDT A small study of patients treated with warfarin for deep vein thrombosis suggests that thyroid autoantibodies may contribute to the instability of International Normalized Ratio (INR) control.

AAN recommends MRI for stroke diagnosis Posted: 14 Jul 2010 05:00 PM PDT A new American Academy of Neurology guideline advises physicians to use magnetic resonance imaging to diagnose acute stroke, because of the superior sensitivity of diffusion-weighted imaging compared with computed tomography.

Genetic polymorphisms improve recurrence prediction after prostate surgery Posted: 14 Jul 2010 05:00 PM PDT Taking genetic as well as clinicopathologic data into account could significantly improve clinicians' ability to predict whether prostate cancer patients treated with radical prostatectomy are likely to experience biological disease recurrence, say Spanish researchers.

Research sheds light on anti-prostate cancer effects of broccoli Posted: 14 Jul 2010 05:00 PM PDT UK study results may help to explain how a diet rich in broccoli could reduce the risk for developing prostate cancer.

Genetic polymorphisms improve recurrence prediction after prostate surgery Posted: 14 Jul 2010 05:00 PM PDT Taking genetic as well as clinicopathologic data into account could significantly improve clinicians' ability to predict whether prostate cancer patients treated with radical prostatectomy are likely to experience biological disease recurrence, say Spanish researchers.

Research sheds light on anti-prostate cancer effects of broccoli Posted: 14 Jul 2010 05:00 PM PDT UK study results may help to explain how a diet rich in broccoli could reduce the risk for developing prostate cancer.

Reduced E-cadherin predicts poor prognosis in triple-negative breast cancer Posted: 14 Jul 2010 05:00 PM PDT Reduced expression of E-cadherin is associated with worse overall and disease-free survival in patients with triple-negative breast cancer, Japanese researchers report.

Missing link in triglyceride metabolism identified Posted: 14 Jul 2010 05:00 PM PDT The molecule GPI-anchored high-density lipoprotein-binding protein 1 is responsible for transporting lipoprotein lipase into the capillaries, shows a study in mice.

<i>ABCA1</i> variant affects CHD risk, statin response in FH patients Posted: 14 Jul 2010 05:00 PM PDT A common variant of the ATP-binding cassette transporter A1 gene increases risk for coronary heart disease in patients with familial hypercholesterolemia, research shows.

Active sun exposure reduces Type 2 diabetes risk in women Posted: 14 Jul 2010 05:00 PM PDT Women who sunbathe and use tanning beds are at significantly lower risk for developing Type 2 diabetes than those with no or very low sun exposure, show study results.

Rising BMI responsible for large proportion Type 2 diabetes increase in men Posted: 14 Jul 2010 05:00 PM PDT The increase in men's average body mass index accounts for a large proportion of the rise in Type 2 diabetes among men in the UK over the past few decades, say researchers.

Radial approach improves PCI outcomes Posted: 14 Jul 2010 05:00 PM PDT Primary percutaneous coronary intervention using a radial access approach reduces major bleeding and major adverse cardiac events compared with a femoral approach, without compromising time to revascularization, a Canadian study suggests.

Is screening for subclinical atherosclerosis worthwhile? Posted: 14 Jul 2010 05:00 PM PDT Screening asymptomatic individuals for subclinical atherosclerosis has the potential to improve cardiovascular disease prevention strategies, but any screening program must yet be proven to prevent actual cardiovascular disease, an editorial viewpoint and commentary suggest.

Reduced E-cadherin predicts poor prognosis in triple-negative breast cancer Posted: 14 Jul 2010 05:00 PM PDT Reduced expression of E-cadherin is associated with worse overall and disease-free survival in patients with triple-negative breast cancer, Japanese researchers report.

AUR after prostate brachytherapy linked to treatment trauma, not dose Posted: 13 Jul 2010 05:00 PM PDT The radiation dose of iodine-125 prostate brachytherapy received to the prostate tissue does not significantly influence a man's risk for developing acute urinary retention, report Dutch researchers.

Sunitinib plus paclitaxel well tolerated in advanced breast cancer Posted: 13 Jul 2010 05:00 PM PDT Sunitinib given in combination with paclitaxel to patients with advanced breast cancer is well tolerated, with evidence of anti-tumor activity and no drug–drug interactions, data from an exploratory study show.

Brachytherapy more efficient than EBRT for prostate cancer Posted: 12 Jul 2010 05:00 PM PDT Prostate-specific antigen kinetics differ following different radiotherapy methods, with brachytherapy having a higher radiobiological efficiency than external-beam radiotherapy, suggest German researchers.

Lymph node metastasis, HER2-status predict recurrence after breast cancer response Posted: 12 Jul 2010 05:00 PM PDT Axillary lymph node metastasis and human epidermal growth factor receptor 2-positive disease are independent predictors for disease recurrence in patients with a pathologic complete response after neoadjuvant chemotherapy for breast cancer, Japanese researchers report.

Clinical prostate cancer stage ‘does not predict recurrence risk’ Posted: 11 Jul 2010 05:00 PM PDT Determining the clinical stage of localized prostate cancer does not offer any independent information on the risk for biochemical recurrence, US scientists have discovered in findings that call into question the usefulness of staging.

Quality of life worsening by IMRT for prostate cancer only temporary Posted: 11 Jul 2010 05:00 PM PDT High-dose intensity-modulated radiotherapy with accurate positioning for localized prostate cancer only temporarily worsens quality of life, the results of a French study indicate.

PET/CT superior to bone scintigraphy for detecting metastatic breast cancer Posted: 11 Jul 2010 05:00 PM PDT US researchers report a high degree of concordance between integrated positron emission tomography/computed tomography and bone scintigraphy for detecting bone metastases in women with breast cancer.

You are subscribed to email updates from MedWire Medical News Combined Feed To stop receiving these emails, you may unsubscribe now.	Email delivery powered by Google
Google Inc., 20 West Kinzie, Chicago IL USA 60610