Medical News

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• Emphysema ‘does not increase mortality in pulmonary fibrosis’
• Parental knowledge of asthma controller medication ‘inadequate’
• Respiratory infections may explain antibiotic link to allergic disease
• Alcohol use may not worsen bipolar disorder outcomes
• Altered hippocampal lipid profile in schizophrenia, bipolar disorder
• Eosinophilic esophagitis often underdiagnosed, misinterpreted
• Lp(a) fails to predict recurrent VTE risk
• Assessing brain infarction boosts ABCD² accuracy
• Researchers shed light on link between high-fat diet and prostate cancer risk
• Higher doses of anastrazole required in overweight breast cancer patients
• Metabolic syndrome has ‘profound influence’ on cholesterol homeostasis
• Statin-treated dyslipidemia patients ‘often not at goal’
• Waist circumference good additional predictor of Type 2 diabetes
• US FDA vote to keep rosiglitazone on the market
• aVR ST elevation signals adverse prognosis in AMI
• US FDA vote to keep rosiglitazone on the market
• On-pump CABG may produce better graft patency outcomes than off-pump

Emphysema ‘does not increase mortality in pulmonary fibrosis’ Posted: 20 Jul 2010 05:00 PM PDT Patients with combined pulmonary fibrosis and emphysema do not have greater mortality rates than those with pulmonary fibrosis alone, study findings suggest.

Parental knowledge of asthma controller medication ‘inadequate’ Posted: 20 Jul 2010 05:00 PM PDT Many parents of children suffering from asthma exacerbations who present to pediatric emergency departments do not understand the importance of daily inhaled corticosteroid treatment, say researchers.

Respiratory infections may explain antibiotic link to allergic disease Posted: 20 Jul 2010 05:00 PM PDT The link between antibiotic use in early life and the development of allergic disease may be partly explained by respiratory infections, say researchers.

Alcohol use may not worsen bipolar disorder outcomes Posted: 20 Jul 2010 05:00 PM PDT Neither moderate nor excessive alcohol consumption has a negative effect on illness course or outcome in patients with bipolar disorder, study results suggest.

Altered hippocampal lipid profile in schizophrenia, bipolar disorder Posted: 20 Jul 2010 05:00 PM PDT The postmortem brains of patients with schizophrenia and bipolar disorder show an altered phospholipid profile, namely a decrease in omega-6 long-chain polyunsaturated fatty acids, study results show.

Eosinophilic esophagitis often underdiagnosed, misinterpreted Posted: 20 Jul 2010 05:00 PM PDT Eosinophilic esophagitis is frequently underdiagnosed due to lack of clinical suspicion, failure to biopsy, and histopathologic misinterpretation, results of a UK study show.

Lp(a) fails to predict recurrent VTE risk Posted: 19 Jul 2010 05:00 PM PDT Measuring serum levels of lipoprotein (Lp)(a) is not a useful way to predict the risk for recurrent venous thromboembolism in first unprovoked VTE patients, suggest study results.

Assessing brain infarction boosts ABCD<sup>2</sup> accuracy Posted: 19 Jul 2010 05:00 PM PDT Incorporating the presence or absence of brain infarction into the ABCD2 system improves the ability of the score to predict stroke in patients with transient ischemic attack, say researchers.

Researchers shed light on link between high-fat diet and prostate cancer risk Posted: 19 Jul 2010 05:00 PM PDT US study results provide evidence that the link between prostate cancer and a high-fat diet hinges on advanced oxidative stress and inflammation of the prostate gland, induced by the activation of nuclear factor-kappa B cells.

Higher doses of anastrazole required in overweight breast cancer patients Posted: 19 Jul 2010 05:00 PM PDT The relative efficacy of anastrozole compared with tamoxifen is greater in postmenopausal women with a healthy weight than in their overweight peers, researchers report.

Metabolic syndrome has ‘profound influence’ on cholesterol homeostasis Posted: 19 Jul 2010 05:00 PM PDT The metabolic syndrome is associated with marked alterations in cholesterol synthesis and absorption, irrespective of other lipid abnormalities, study findings suggest.

Statin-treated dyslipidemia patients ‘often not at goal’ Posted: 19 Jul 2010 05:00 PM PDT A significant proportion of high-risk dyslipidemic individuals are not achieving their treatment goals despite using statins, a French team has found.

Waist circumference good additional predictor of Type 2 diabetes Posted: 19 Jul 2010 05:00 PM PDT Waist circumference is a valuable additional factor for Type 2 diabetes prediction, particularly among individuals with a low or normal body mass index, say researchers.

US FDA vote to keep rosiglitazone on the market Posted: 19 Jul 2010 05:00 PM PDT A US Food and Drug Administration advisory committee has voted to keep the Type 2 diabetes drug rosiglitazone on the market, but suggested that the labeling needs to be changed to include increased warnings.

aVR ST elevation signals adverse prognosis in AMI Posted: 19 Jul 2010 05:00 PM PDT The presence of ST elevation in lead aVR during ST elevation myocardial infarction is associated with increased mortality, a study reports.

US FDA vote to keep rosiglitazone on the market Posted: 19 Jul 2010 05:00 PM PDT A US Food and Drug Administration advisory committee has voted to keep the Type 2 diabetes drug rosiglitazone on the market, but suggested that the labeling needs to be changed to include increased warnings.

On-pump CABG may produce better graft patency outcomes than off-pump Posted: 19 Jul 2010 05:00 PM PDT Coronary artery bypass graft surgery performed on-pump reduces the risk for early graft occlusion compared with off-pump, Portuguese researchers report.

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