Medical News

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• Inhaled corticosteroids may increase cataract risk
• TLR7 function reduced in young asthmatics
• Multiple factors linked to cardiac troponin T elevation in COPD
• Schizophrenia diagnosis impacts cervical cancer screening rates
• White matter alterations present early in the course of BD
• Anti-TNF-α associated psoriasiform lesions are new model of drug reaction
• IGRAs superior for latent tuberculosis screening in psoriasis
• National Psoriasis Foundation advises on HIV-associated psoriasis treatment
• Psoriasis vulgaris linked to pro-atherogenic risk factors
• Rivaroxaban superior to LMWH for knee surgery VTE prevention
• Unilateral anesthesia possible with bupivacaine–clonidine combination
• Rapid onset of supraclavicular block questioned
• Anesthesia technique allows patient co-operation during carotid surgery
• LEFt variables predict DVT in pregnant women
• Chronic beta-blocker use ‘does not raise perioperative stroke risk’
• Selenium levels linked to aggressive prostate cancer depending on SOD2 genotype
• Height linked to increased risk for aggressive prostate cancer
• Local anesthetic reduces SLN biopsy pain
• Selenium levels linked to aggressive prostate cancer depending on SOD2 genotype
• Height linked to increased risk for aggressive prostate cancer
• Oxidized lipoprotein(a) levels rise with CAD severity
• Preβ-1 HDL raised in all forms of dyslipidemia
• Triple, pioglitazone containing oral regimen gives long-term glycemic control
• Low SHBG strongly predicts risk for Type 2 diabetes
• Multivessel PCI in STEMI called into question
• Delayed hypersensitivity reaction a likely cause of very late DES thrombosis
• Local anesthetic reduces SLN biopsy pain
• Growth factor binding protein levels point to prostate cancer death
• Breast cancer treatment practice shows regional and age differences
• Long-term prostate cancer mortality following surgery ‘low’
• Continued relationship with physician improves prostate cancer screening rates
• Skin telangiectasiae predicts radiation-induced CVD in breast cancer
• Prostate cancer control with hypofractionated EBRT feasible
• Hot flashes in breast cancer survivors unaffected by tryptophan levels

Inhaled corticosteroids may increase cataract risk Posted: 06 Aug 2009 05:00 PM PDT The use of inhaled corticosteroids may increase the risk for cataracts in a dose-dependent manner, results of a meta-analysis show.

TLR7 function reduced in young asthmatics Posted: 06 Aug 2009 05:00 PM PDT Toll-like receptor 7 function is reduced in adolescents with asthma, which may account for their increased susceptibility to respiratory infections, say researchers.

Multiple factors linked to cardiac troponin T elevation in COPD Posted: 06 Aug 2009 05:00 PM PDT Multiple factors are associated with elevated cardiac troponin T levels in patients with chronic obstructive pulmonary disease, reflecting the wide variety of comorbidities typically seen in patients with the lung condition, say researchers.

Schizophrenia diagnosis impacts cervical cancer screening rates Posted: 06 Aug 2009 05:00 PM PDT Women with schizophrenia are less likely to receive cervical cancer screening than women in the general population, suggests a population-based study undertaken in Manitoba, Canada.

White matter alterations present early in the course of BD Posted: 06 Aug 2009 05:00 PM PDT US researchers have found significant white matter tract alterations in adolescent patients with bipolar disorder within pathways involved in emotional, behavioral, and cognitive regulation.

Anti-TNF-α associated psoriasiform lesions are new model of drug reaction Posted: 06 Aug 2009 05:00 PM PDT Psoriasiform eruptions that occur in association with anti-tumour necrosis factor-α therapy are a new model of drug reaction and differ from true psoriasis, say researchers.

IGRAs superior for latent tuberculosis screening in psoriasis Posted: 06 Aug 2009 05:00 PM PDT Study findings support the use of interferon-γ; release assays instead of the tuberculin skin test for identifying latent tuberculosis infection in psoriasis patients before they start antitumour necrosis factor-α therapy.

National Psoriasis Foundation advises on HIV-associated psoriasis treatment Posted: 06 Aug 2009 05:00 PM PDT The Medical Board of the National Psoriasis Foundation in the USA has issued recommendations for the treatment of psoriasis in patients with HIV.

Psoriasis vulgaris linked to pro-atherogenic risk factors Posted: 06 Aug 2009 05:00 PM PDT Psoriasis vulgaris is a pro-atherogenic condition, say researchers who found the condition was associated with dyslipidemia, inflammation, overweight and obesity.

Rivaroxaban superior to LMWH for knee surgery VTE prevention Posted: 06 Aug 2009 05:00 PM PDT Results from the RECORD4 trial show that the oral direct factor Xa inhibitor rivaroxaban is superior to the low molecular weight heparin enoxaparin for the prevention of venous thromboembolism following knee replacement surgery.

Unilateral anesthesia possible with bupivacaine–clonidine combination Posted: 06 Aug 2009 05:00 PM PDT Unilateral spinal anesthesia can be achieved when bupivacaine is combined with clonidine, but clonidine does prolong the motor block and increase the need for vasopressors, researchers report.

Rapid onset of supraclavicular block questioned Posted: 06 Aug 2009 05:00 PM PDT Ultrasound-guided administration of local anesthestic to the "corner pocket" inferolateral to the subclavian artery does not provide a more rapid onset of brachial plexus block than triple point injection around the axillary artery, study findings show.

Anesthesia technique allows patient co-operation during carotid surgery Posted: 06 Aug 2009 05:00 PM PDT Researchers have developed a new technique of general anesthesia that allows neurological monitoring of awake patients during surgery.

LEFt variables predict DVT in pregnant women Posted: 05 Aug 2009 05:00 PM PDT Canadian researchers have devised a pretest probability assessment that may be able to rule out deep vein thrombosis in pregnancy.

Chronic beta-blocker use ‘does not raise perioperative stroke risk’ Posted: 05 Aug 2009 05:00 PM PDT Chronic beta-blocker use in patients undergoing noncardiac surgery is not associated with an increased risk for stroke, a case–control study has demonstrated.

Selenium levels linked to aggressive prostate cancer depending on SOD2 genotype Posted: 05 Aug 2009 05:00 PM PDT Men diagnosed with prostate cancer who have a particular variant of the gene manganese superoxide dismutase are at increased risk for a more aggressive form of the disease if they also have high levels of plasma selenium in the body, research findings show.

Height linked to increased risk for aggressive prostate cancer Posted: 05 Aug 2009 05:00 PM PDT Men under the age of 65 years with prostate cancer are at increased risk for developing aggressive forms of the disease if they are tall, a US cancer screening trial indicates.

Local anesthetic reduces SLN biopsy pain Posted: 05 Aug 2009 05:00 PM PDT Adding the local anesthetic lidocaine to the radiocolloid injection reduces the pain of sentinel lymph node biopsy in breast cancer patients, a US trial shows.

Selenium levels linked to aggressive prostate cancer depending on SOD2 genotype Posted: 05 Aug 2009 05:00 PM PDT Men diagnosed with prostate cancer who have a particular variant of the gene manganese superoxide dismutase are at increased risk for a more aggressive form of the disease if they also have high levels of plasma selenium in the body, research findings show.

Height linked to increased risk for aggressive prostate cancer Posted: 05 Aug 2009 05:00 PM PDT Men under the age of 65 years with prostate cancer are at increased risk for developing aggressive forms of the disease if they are tall, a US cancer screening trial indicates.

Oxidized lipoprotein(a) levels rise with CAD severity Posted: 05 Aug 2009 05:00 PM PDT Elevated levels of oxidized lipoprotein (ox-Lp)(a) are associated with the presence and severity of coronary artery disease, study findings reveal.

Preβ-1 HDL raised in all forms of dyslipidemia Posted: 05 Aug 2009 05:00 PM PDT Levels of the preβ-1 subclass of high-density lipoprotein particles are markedly increased in dyslipidemic patients, a study by Greek researchers has revealed.

Triple, pioglitazone containing oral regimen gives long-term glycemic control Posted: 05 Aug 2009 05:00 PM PDT Use of a triple oral regimen adding pioglitazone to metformin–sulfonylurea therapy provides effective long-term glycemic control and reduces insulin requirements in patients with Type 2 diabetes, a post-hoc analysis of PROactive shows.

Low SHBG strongly predicts risk for Type 2 diabetes Posted: 05 Aug 2009 05:00 PM PDT Low levels of circulating sex hormone-binding globulin are strongly predictive for Type 2 diabetes in women and men, report researchers in the New England Journal of Medicine.

Multivessel PCI in STEMI called into question Posted: 05 Aug 2009 05:00 PM PDT Study findings suggest that multivessel percutaneous coronary intervention does not improve survival among ST-elevation myocardial infarction patients, even those with cardiogenic shock.

Delayed hypersensitivity reaction a likely cause of very late DES thrombosis Posted: 05 Aug 2009 05:00 PM PDT A study of thrombus aspirate histopathology and intravascular ultrasound findings in patients with very late drug-eluting stent thrombosis reveals that the degree of eosinophilic infiltration correlates with the extent of stent malapposition.

Local anesthetic reduces SLN biopsy pain Posted: 05 Aug 2009 05:00 PM PDT Adding the local anesthetic lidocaine to the radiocolloid injection reduces the pain of sentinel lymph node biopsy in breast cancer patients, a US trial shows.

Growth factor binding protein levels point to prostate cancer death Posted: 04 Aug 2009 05:00 PM PDT An increased risk for prostate cancer-specific death is associated with circulating levels of intact insulin-like growth factor binding protein 3 at diagnosis, study findings suggest.

Breast cancer treatment practice shows regional and age differences Posted: 04 Aug 2009 05:00 PM PDT Variations in breast cancer treatment persists nationally, the UK Breast Cancer Clinical Outcome Measures project shows.

Long-term prostate cancer mortality following surgery ‘low’ Posted: 03 Aug 2009 05:00 PM PDT Few patients die from prostate cancer within 15 years of radical prostatectomy, regardless of the presence of adverse clinical features, say US researchers who call for novel markers to identify lethal prostate cancer.

Continued relationship with physician improves prostate cancer screening rates Posted: 03 Aug 2009 05:00 PM PDT A continued relationship with a trusted healthcare provider and a regular source of care increases rates of screening for prostate cancer in men over the age of 50 years, say US researchers.

Skin telangiectasiae predicts radiation-induced CVD in breast cancer Posted: 03 Aug 2009 05:00 PM PDT Skin telangiectasiae in women who have undergone irradiation for breast cancer treatment,predicts the risk for cardiovascular disease, a UK study suggests.

Prostate cancer control with hypofractionated EBRT feasible Posted: 02 Aug 2009 05:00 PM PDT Hypofractionation of three-dimensional conformal external-beam radiotherapy for localized prostate cancer does not reduce biochemical control versus standard fractionation, say scientists.

Hot flashes in breast cancer survivors unaffected by tryptophan levels Posted: 02 Aug 2009 05:00 PM PDT In women who have survived breast cancer, physiologically measured and self-reported hot flashes are not increased by acute tryptophan depletion, study results suggest.

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