Medical News

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• Traditional factors do not predict asthma risk in highly adherent patients
• Interval- and constant-load training equally effective in COPD
• COPD patients often underestimate disease severity
• Novel scale describes reasons for substance use in schizophrenia
• Oxidative stress linked to early schizophrenia pathophysiology
• Biologic agent use in inflammatory diseases varies with age and gender
• Fish oils and climatotherapy promising alternative therapies for psoriasis
• Switching to etanercept effective for psoriasis patients
• Cyclosporine and infliximab recommended for erythrodermic psoriasis
• Psoriasis patients say dermatologists need better communication skills
• Thrombectomy plus thrombolysis effective for massive DVT
• MRI predicts hemorrhage risk in acute stroke
• Comparable outcomes with open and laparoscopic radical prostatectomy
• Weight lifting may improve breast cancer related lymphedema
• Comparable outcomes with open and laparoscopic radical prostatectomy
• Vitamin D deficiency accelerates atherosclerosis development in diabetes
• No link between low LCAT and increased atherosclerosis
• CHD risk not associated with APOE genotype in EPIC-Norfolk
• Central arterial stiffness linked to diabetes microvascular complications
• Vitamin D deficiency accelerates atherosclerosis development in diabetes
• Persistent anemia after AMI raises mortality, heart failure risk
• More patients with AMI being screened for ejection fraction
• Weight lifting may improve breast cancer related lymphedema
• Biochemical recurrence risk low with negative tissue after positive surgery margin
• SPPI is an ‘excellent’ therapeutic option for patients with recurrent prostate cancer
• AI-related arthralgia inversely associated with time since menopause
• CYP3A4 enzyme implicated in prostate cancer development
• Breast feeding reduces familial breast cancer risk
• Prostate cancer gene link to adverse features unaffected by diabetes
• Pretreatment PSA dynamics do not improve outcome prediction
• Decision to undergo breast cancer risk-reducing surgery is multifactorial

Traditional factors do not predict asthma risk in highly adherent patients Posted: 13 Aug 2009 05:00 PM PDT Most of the usual indicators of future disease activity in asthma patients have little predictive power when applied to highly adherent patients with persistent asthma who are receiving guideline-based care, say researchers.

Interval- and constant-load training equally effective in COPD Posted: 13 Aug 2009 05:00 PM PDT Interval-load training is just as effective for improving functional capacity in chronic obstructive pulmonary disease patients as constant-load training, study results show.

COPD patients often underestimate disease severity Posted: 13 Aug 2009 05:00 PM PDT Many patients with chronic obstructive pulmonary disease underestimate the severity of their condition, study findings suggest.

Novel scale describes reasons for substance use in schizophrenia Posted: 13 Aug 2009 05:00 PM PDT A novel scale reliably assesses the self-reported reasons for substance use in schizophrenia and their relationship to psychotic symptoms, conclude UK researchers.

Oxidative stress linked to early schizophrenia pathophysiology Posted: 13 Aug 2009 05:00 PM PDT Oxidative stress appears to be increased in the acute stage of a schizophrenic episode and may play a role in the pathogenesis and symptomatology of the condition, study findings indicate.

Biologic agent use in inflammatory diseases varies with age and gender Posted: 13 Aug 2009 05:00 PM PDT The average switch/stop rate for biologic therapy in older men with inflammatory diseases appears to be higher than that for younger men and for women, study findings suggest.

Fish oils and climatotherapy promising alternative therapies for psoriasis Posted: 13 Aug 2009 05:00 PM PDT A review of randomised clinical trials shows that fish oils, climatotherapy and mind/body interventions are the most promising alternative therapies for psoriasis.

Switching to etanercept effective for psoriasis patients Posted: 13 Aug 2009 05:00 PM PDT Etanercept is an effective treatment option for psoriasis in patients who have failed to respond to traditional and other biologic therapies, researchers report.

Cyclosporine and infliximab recommended for erythrodermic psoriasis Posted: 13 Aug 2009 05:00 PM PDT The medical board for the National Psoriasis Foundation in the USA recommends the use of cyclosporine and infliximab as the fastest acting first-line agents in the treatment of erythrodermic psoriasis.

Psoriasis patients say dermatologists need better communication skills Posted: 13 Aug 2009 05:00 PM PDT Survey findings indicate that dermatologists treating patients with psoriasis need to listen to their patients, use simple language and improve their psychological and interpersonal skills.

Thrombectomy plus thrombolysis effective for massive DVT Posted: 12 Aug 2009 05:00 PM PDT Percutaneous mechanical thromboectomy with catheter-direct thrombolysis is feasible for the treatment of patients with massive symptomatic lower limb deep vein thrombosis, say Chinese researchers.

MRI predicts hemorrhage risk in acute stroke Posted: 12 Aug 2009 05:00 PM PDT Using magnetic resonance imaging to measure blood–brain barrier disruption may predict the risk for hemorrhagic transformation after thrombolytic therapy, a Canadian team has shown.

Comparable outcomes with open and laparoscopic radical prostatectomy Posted: 12 Aug 2009 05:00 PM PDT Patients with clinically localized prostate cancer can be effectively treated using radical prostatectomy, with open and laparoscopic techniques having similar functional outcomes, the results of a US study indicate.

Weight lifting may improve breast cancer related lymphedema Posted: 12 Aug 2009 05:00 PM PDT Weight lifting reduces the number and severity of hand and arm symptoms, increases muscular strength, and reduces the incidence of lymphedema exacerbations in female breast cancer survivors, research shows.

Comparable outcomes with open and laparoscopic radical prostatectomy Posted: 12 Aug 2009 05:00 PM PDT Patients with clinically localized prostate cancer can be effectively treated using radical prostatectomy, with open and laparoscopic techniques having similar functional outcomes, the results of a US study indicate.

Vitamin D deficiency accelerates atherosclerosis development in diabetes Posted: 12 Aug 2009 05:00 PM PDT Vitamin D deficiency contributes to the increase in macrophage-mediated cholesterol deposition observed in patients with diabetes, report researchers in the journal Circulation.

No link between low LCAT and increased atherosclerosis Posted: 12 Aug 2009 05:00 PM PDT Low levels of lecithin:cholesterol acyltransferase are not linked to an increased risk for atherosclerosis in the general population, report researchers.

CHD risk not associated with APOE genotype in EPIC-Norfolk Posted: 12 Aug 2009 05:00 PM PDT Results from a large prospective study show that risk for coronary heart disease is not associated with apolipoprotein E genotype even after adjustment for a variety of cardiovascular risk factors.

Central arterial stiffness linked to diabetes microvascular complications Posted: 12 Aug 2009 05:00 PM PDT Diabetic retinopathy and nephropathy are associated with increased central aortic stiffness in patients with Type 2 diabetes, independent of other established determinants of aortic stiffness, cross-sectional study findings suggest.

Vitamin D deficiency accelerates atherosclerosis development in diabetes Posted: 12 Aug 2009 05:00 PM PDT Vitamin D deficiency contributes to the increase in macrophage-mediated cholesterol deposition observed in patients with diabetes, report researchers in the journal Circulation.

Persistent anemia after AMI raises mortality, heart failure risk Posted: 12 Aug 2009 05:00 PM PDT A substantial number of patients discharged after acute myocardial infarction subsequently develop persistent or new-onset anemia, which carries an elevated risk for mortality and heart failure, research suggests.

More patients with AMI being screened for ejection fraction Posted: 12 Aug 2009 05:00 PM PDT An increasing number of patients with acute myocardial infarction are being assessed for left ventricular ejection fraction, in accordance with recommended guidelines, results of an observational study suggest.

Weight lifting may improve breast cancer related lymphedema Posted: 12 Aug 2009 05:00 PM PDT Weight lifting reduces the number and severity of hand and arm symptoms, increases muscular strength, and reduces the incidence of lymphedema exacerbations in female breast cancer survivors, research shows.

Biochemical recurrence risk low with negative tissue after positive surgery margin Posted: 11 Aug 2009 05:00 PM PDT Prostate cancer patients who have positive surgical margins after radical prostatectomy and subsequent negative resected tissue display similar disease behavior to those with negative surgical margins, study findings show.

SPPI is an ‘excellent’ therapeutic option for patients with recurrent prostate cancer Posted: 11 Aug 2009 05:00 PM PDT Prostate cancer patients with localized recurrence of the disease following external beam radiotherapy have significantly improved chances of controlling their cancer with salvage permanent perineal radioactive-seed implantation, findings suggest.

AI-related arthralgia inversely associated with time since menopause Posted: 11 Aug 2009 05:00 PM PDT Breast cancer survivors who have recently experienced menopause are more likely to report aromatase inhibitor-related arthralgia than those who are 10 or more years past menopause, US researchers report.

CYP3A4 enzyme implicated in prostate cancer development Posted: 10 Aug 2009 05:00 PM PDT Decreased expression of the cytochrome P450 3A4 enzyme contributes to the development of prostate cancer and provides clues to possible targets for new treatment, say researchers.

Breast feeding reduces familial breast cancer risk Posted: 10 Aug 2009 05:00 PM PDT Breastfeeding may more than halve the risk for breast cancer in women with a family history of the disease, US study results show.

Prostate cancer gene link to adverse features unaffected by diabetes Posted: 09 Aug 2009 05:00 PM PDT The presence of diabetes mellitus does not significantly affect the relationship between the prostate cancer risk variant at chromosome 17q12 and adverse tumor features, the results of a US study indicate.

Pretreatment PSA dynamics do not improve outcome prediction Posted: 09 Aug 2009 05:00 PM PDT Predictions of outcome for men undergoing treatment for prostate cancer are not significantly improved by pretreatment prostate-specific antigen velocity and doubling time measurements, research shows.

Decision to undergo breast cancer risk-reducing surgery is multifactorial Posted: 09 Aug 2009 05:00 PM PDT The uptake of risk-reducing surgery in women at increased risk for breast and ovarian cancer depends on risk, time and age, study findings indicate.

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