Medical News

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• Brain imaging urged for wake-up stroke patients
• Two questions could help target COPD screening
• Abdominal muscle fatigue occurs in COPD patients when exercising
• <i>NOS2A</i> gene variants linked to respiratory health in children
• Exercise stimulates hippocampal plasticity in schizophrenia patients
• Bipolar mixed states linked to active religious involvement
• Twice, rather than once, weekly etanercept offers skin but not joint benefits
• Reflux symptoms more prevalent among wind instrument players
• Fondaparinux ACS treatment patterns examined in France
• Acute ischemic stroke patients with hyperlipidemia have less severe WMH
• Hospitalizations after TRUS-guided prostate biopsy increased during 1996–2005
• Low molecular weight cyclin-E mediates letrozole resistance
• Hospitalizations after TRUS-guided prostate biopsy increased during 1996–2005
• Rosuvastatin approved by US FDA for primary prevention of CVD
• Acute ischemic stroke patients with hyperlipidemia have less severe WMH
• Socioeconomic status inversely linked with Type 2 diabetes risk
• Cell adhesion molecules in pregestational diabetes linked with vasculopathy
• Absence of coronary calcification does not rule out obstructive CAD
• Cross-country skiers show markedly elevated rate of lone AF
• Low molecular weight cyclin-E mediates letrozole resistance
• Age-adjusted median PSA not the best predictor for prostate cancer risk
• Prostate cancer aggressiveness predicts positive surgical margins
• Adjuvant therapy decision not based on axillary node involvement
• PSA screening for prostate cancer is less sensitive in USA than European trial
• Raised vitamin D linked to pregnancy-associated breast cancer
• Men undergoing radiotherapy for prostate cancer risk chronic fatigue
• Prostate surgery patients could go home on same day as surgery
• Fibronectin 1 and CXCL9 candidate biomarkers for breast cancer screening

Brain imaging urged for wake-up stroke patients Posted: 11 Feb 2010 04:00 PM PST A brain imaging study of patients with wake-up stroke shows that they are as likely to have salvageable brain tissue as patients with a known time of symptom onset.

Two questions could help target COPD screening Posted: 11 Feb 2010 04:00 PM PST Two questions relating to smoking and cough/dyspnea can help identify at-risk patients who would benefit from chronic obstructive pulmonary disease screening, say researchers.

Abdominal muscle fatigue occurs in COPD patients when exercising Posted: 11 Feb 2010 04:00 PM PST Patients with chronic obstructive pulmonary disease develop abdominal muscle fatigue when exercising to exhaustion, which may be related to exercise limitation in such patients, say researchers.

<i>NOS2A</i> gene variants linked to respiratory health in children Posted: 11 Feb 2010 04:00 PM PST Common haplotypes in the NOS2A promoter region are associated with new-onset asthma and lung function growth in children, US researchers have found.

Exercise stimulates hippocampal plasticity in schizophrenia patients Posted: 11 Feb 2010 04:00 PM PST The hippocampus in patients with schizophrenia retains a degree of plasticity despite being smaller than normal,, say researchers who found increases in hippocampal volume among patients following an aerobic exercise program.

Bipolar mixed states linked to active religious involvement Posted: 11 Feb 2010 04:00 PM PST Bipolar disorder patients in mixed states appear to have more active private religious lives, including prayer or meditation, compared with their counterparts in depressed, manic, or euthymic states, US researchers report.

Twice, rather than once, weekly etanercept offers skin but not joint benefits Posted: 11 Feb 2010 04:00 PM PST Twice weekly treatment with 50 mg of etanercept appears to be superior to once weekly treatment for the clearance of skin lesions in patients with psoriasis and psoriatic arthritis, findings from the PRESTA study show.

Reflux symptoms more prevalent among wind instrument players Posted: 11 Feb 2010 04:00 PM PST Typical reflux symptoms such as heartburn and belching are more common among wind instrument players than other instrument players, researchers have found.

Fondaparinux ACS treatment patterns examined in France Posted: 10 Feb 2010 04:00 PM PST Fondaparinux has increasingly been used in French patients with acute coronary syndromes as an alternative to unfractionated heparin or low molecular weight heparin, study findings suggest.

Acute ischemic stroke patients with hyperlipidemia have less severe WMH Posted: 10 Feb 2010 04:00 PM PST Patients with acute ischemic stroke who have a history of hyperlipidemia have less severe white matter hyperintensity at the time of stroke than normolipidemic individuals, show study results.

Hospitalizations after TRUS-guided prostate biopsy increased during 1996–2005 Posted: 10 Feb 2010 04:00 PM PST Rates of hospital admission after transrectal ultrasound-guided prostate biopsy rose dramatically between 1996 and 2005, but mortality rates following the procedure did not, study findings show.

Low molecular weight cyclin-E mediates letrozole resistance Posted: 10 Feb 2010 04:00 PM PST Overexpression of low molecular weight forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen receptor-positive breast cancers, US researchers report.

Hospitalizations after TRUS-guided prostate biopsy increased during 1996–2005 Posted: 10 Feb 2010 04:00 PM PST Rates of hospital admission after transrectal ultrasound-guided prostate biopsy rose dramatically between 1996 and 2005, but mortality rates following the procedure did not, study findings show.

Rosuvastatin approved by US FDA for primary prevention of CVD Posted: 10 Feb 2010 04:00 PM PST The US Food and Drug Administration has approved rosuvastatin for use in primary prevention of cardiovascular disease, the first statin to be approved for this indication.

Acute ischemic stroke patients with hyperlipidemia have less severe WMH Posted: 10 Feb 2010 04:00 PM PST Patients with acute ischemic stroke who have a history of hyperlipidemia have less severe white matter hyperintensity at the time of stroke than normolipidemic individuals, show study results.

Socioeconomic status inversely linked with Type 2 diabetes risk Posted: 10 Feb 2010 04:00 PM PST The risk for Type 2 diabetes is greatest in people with the lowest educational and income levels, a Canadian study has found.

Cell adhesion molecules in pregestational diabetes linked with vasculopathy Posted: 10 Feb 2010 04:00 PM PST Pregnant women with diabetes show fluctuations in levels of cell adhesion molecules, say Polish researchers who suggest that these effects may underlie the increased risk for complications seen in diabetic pregnancies.

Absence of coronary calcification does not rule out obstructive CAD Posted: 10 Feb 2010 04:00 PM PST The absence of coronary artery calcification does not exclude obstructive stenosis or the need for revascularization in patients with suspected coronary artery disease, study results demonstrate.

Cross-country skiers show markedly elevated rate of lone AF Posted: 10 Feb 2010 04:00 PM PST Around 13% of elite cross-country skiers have a history of lone atrial fibrillation, report researchers who note that this is the highest prevalence yet described in long-term endurance athletes.

Low molecular weight cyclin-E mediates letrozole resistance Posted: 10 Feb 2010 04:00 PM PST Overexpression of low molecular weight forms of the protein cyclin E renders the aromatase inhibitor letrozole ineffective among women with estrogen receptor-positive breast cancers, US researchers report.

Age-adjusted median PSA not the best predictor for prostate cancer risk Posted: 09 Feb 2010 04:00 PM PST A man's initial prostate-specific antigen reading is significantly associated with his risk for subsequent prostate cancer if it is higher than the average PSA level for his age group, study findings confirm.

Prostate cancer aggressiveness predicts positive surgical margins Posted: 09 Feb 2010 04:00 PM PST Characteristics of aggressive prostate cancer including high clinical stage, pathologic stage, and tumor volume predict positive surgical margins after robot-assisted laparoscopic radical prostatectomy, say researchers.

Adjuvant therapy decision not based on axillary node involvement Posted: 09 Feb 2010 04:00 PM PST Patients who undergo axillary radiation therapy are no less likely to receive adjuvant therapy for breast cancer than those who undergo axillary lymph node dissection, study findings indicate.

PSA screening for prostate cancer is less sensitive in USA than European trial Posted: 08 Feb 2010 04:00 PM PST A Dutch research team has shown that prostate-specific antigen screening protocols in the USA are less effective at identifying prostate cancer than those used in the European Randomized Study of Screening for Prostate Cancer.

Raised vitamin D linked to pregnancy-associated breast cancer Posted: 08 Feb 2010 04:00 PM PST A prospective study among pregnant Finnish women has revealed no association between vitamin D and premenopausal breast cancer, but did show that raised circulating vitamin D levels may be linked to an increased risk for pregnancy-associated breast cancer.

Men undergoing radiotherapy for prostate cancer risk chronic fatigue Posted: 07 Feb 2010 04:00 PM PST A significantly larger proportion of prostate cancer patients treated with definitive radiotherapy report chronic fatigue 1 year after treatment than their radical prostatectomy-treated counterparts, report researchers.

Prostate surgery patients could go home on same day as surgery Posted: 07 Feb 2010 04:00 PM PST Results of a US feasibility study show that robot-assisted radical prostatectomy can be undertaken as an outpatient procedure with no adverse consequences for patient satisfaction or safety.

Fibronectin 1 and CXCL9 candidate biomarkers for breast cancer screening Posted: 07 Feb 2010 04:00 PM PST Gene expression profiling has identified fibronectin 1 and chemokine ligand 9 as candidate biomarkers for breast cancer screening, French researchers report.

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