Medical News

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• Asthma risk high among Canadians
• <i>Haemophilus influenza</i> common in sputum of COPD patients
• Five distinct asthma phenotypes identified
• Premorbid developmental deficits, lags present in children who develop schizophrenia
• Shortened Hypomania Checklist effectively discriminates BD from MDD
• IBD development linked to various childhood factors
• REACH registry reveals US aspirin use
• Intensive medical therapy reduces carotid revascularization need
• Clusterin level, density could predict prostate cancer disease extension
• Web-based nomogram predicts ipsilateral breast tumor risk with varied accuracy
• Vitamin E impacts cholesterol metabolism in the intestine
• Immunomodulatory therapy shows early promise in atherothrombosis
• Treating hypertension could offer cognitive boon
• GAD antibodies predict diabetes independently of family history
• BMI and waist circumference predict Type 2 diabetes risk
• Treating hypertension could offer cognitive boon
• Chronic nitrate use associated with shift to NSTE-ACS

Asthma risk high among Canadians Posted: 15 Feb 2010 04:00 PM PST Results from a Canadian study suggest one in three people who live in Ontario will receive a diagnosis of asthma at some point during their lifetime.

<i>Haemophilus influenza</i> common in sputum of COPD patients Posted: 15 Feb 2010 04:00 PM PST Haemophilus influenza is the most common potentially pathogenic microorganism found in the sputum of patients with stable chronic obstructive pulmonary disease, and is associated with bronchial inflammation in a dose-response manner, research shows.

Five distinct asthma phenotypes identified Posted: 15 Feb 2010 04:00 PM PST Cluster analysis has revealed five distinct clinical phenotypes of asthma, suggesting that current classification and management approaches do not reflect variability in disease expression and severity, say US researchers.

Premorbid developmental deficits, lags present in children who develop schizophrenia Posted: 15 Feb 2010 04:00 PM PST Study findings suggest that children who develop schizophrenia in adulthood struggle with verbal reasoning in primary school and lag behind their peers in working memory, attention, and processing speed as they get older.

Shortened Hypomania Checklist effectively discriminates BD from MDD Posted: 15 Feb 2010 04:00 PM PST Researchers have found that a shortened 16-item version of the Hypomania Checklist reliably differentiates between patients with bipolar disorder and major depressive disorder, without loss in sensitivity or specificity compared with the full version of the questionnaire.

IBD development linked to various childhood factors Posted: 15 Feb 2010 04:00 PM PST Researchers have confirmed the association of a number of childhood factors and the development of inflammatory bowel disease, suggesting that childhood environment plays an important role in modulating the subsequent risk for developing the condition.

REACH registry reveals US aspirin use Posted: 14 Feb 2010 04:00 PM PST Findings from the REACH Registry reveal that around a quarter of US patients who have atherothrombosis or are at significant risk for the condition are not treated with aspirin and many receive no antithrombotic therapy at all.

Intensive medical therapy reduces carotid revascularization need Posted: 14 Feb 2010 04:00 PM PST Use of intensive medical therapy markedly reduces cardiovascular event rates in patients with asymptomatic carotid stenosis, making revascularization unnecessary in most cases, shows research.

Clusterin level, density could predict prostate cancer disease extension Posted: 14 Feb 2010 04:00 PM PST Research findings suggest that the serum level and density of clusterin in men with prostate cancer could be used as a biomarker for estimating disease extension.

Web-based nomogram predicts ipsilateral breast tumor risk with varied accuracy Posted: 14 Feb 2010 04:00 PM PST IBTR! version 2.0, a web-based predictive nomogram for ipsilateral breast tumor recurrence after breast conserving therapy, accurately predicts IBTR risk in most low-to-moderate risk patients but still overestimates risk in a minority of patients with higher risk features, research shows.

Vitamin E impacts cholesterol metabolism in the intestine Posted: 14 Feb 2010 04:00 PM PST Vitamin E decreases endogenous cholesterol synthesis and apolipoprotein-AI-mediated cholesterol secretion in intestinal cells, French scientists have shown.

Immunomodulatory therapy shows early promise in atherothrombosis Posted: 14 Feb 2010 04:00 PM PST Short-term immunosuppressive therapy with mycophenolate mofetil induces changes in atherosclerotic plaque phenotype, a randomized study has shown.

Treating hypertension could offer cognitive boon Posted: 14 Feb 2010 04:00 PM PST Treating hypertension could prevent a third of patients with isolated executive dysfunction from progressing to dementia, show findings from the Canadian Study of Health and Aging.

GAD antibodies predict diabetes independently of family history Posted: 14 Feb 2010 04:00 PM PST Individuals who are positive for glutamic acid decarboxylase antibodies are at increased risk for developing diabetes, irrespective of any family history of the condition, report researchers.

BMI and waist circumference predict Type 2 diabetes risk Posted: 14 Feb 2010 04:00 PM PST Body mass index and waist circumference are similarly predictive of Type 2 diabetes in elderly men, show study results.

Treating hypertension could offer cognitive boon Posted: 14 Feb 2010 04:00 PM PST Treating hypertension could prevent a third of patients with isolated executive dysfunction from progressing to dementia, show findings from the Canadian Study of Health and Aging.

Chronic nitrate use associated with shift to NSTE-ACS Posted: 14 Feb 2010 04:00 PM PST The proportion of non-ST-segment elevation acute coronary syndrome diagnoses was markedly increased among prior chronic users of nitrate therapy enrolled in the Global Registry of Acute Coronary Events, research shows.

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