Medical News

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• Obesity impacting stroke incidence, mortality in China
• Eosinophilic bronchitis ‘does not respond to bronchial challenge’
• FeNO may predict treatment response in COPD exacerbations
• <i>NPSR1</i> gene link to asthma and atopy confirmed
• Sleep efficiency and variability important bipolar treatment targets
• Near-infrared spectroscopy helps identify schizophrenia patients
• Incidental findings frequent with MRI for Crohn's disease
• Clotting factors linked to vascular dementia
• Prostate-specific antigen isoform p2PSA aids prostate cancer detection
• Prostate-specific antigen isoform p2PSA aids prostate cancer detection
• Recommendations for management of sentinal node micrometastases ignored
• Coffee consumption reduces inflammation and increases HDL cholesterol
• <i>APOA</i> gene polymorphisms influence effect of dietary fat on LDL particle size
• VLDL cholesterol predicts coronary risk in Chinese population
• Coffee consumption reduces inflammation and increases HDL cholesterol
• Women with GDM have increased risk for developing Type 2 diabetes
• ICTUS 5-year data show no benefit of early invasive strategy
• Femoral vascular closure device linked to reduced major access site bleeding
• Recommendations for management of sentinal node micrometastases ignored
• TIMP-3 shows potential as gene therapy for prostate cancer
• Prostate cancer detection rate high with transperineal template-guided mapping
• Migraine linked to reduced breast cancer risk
• Metastasis after treatment for prostate cancer depends on disease risk
• <i>p53</i> mutation links deprivation to poor breast cancer outcome
• Postoperative outcomes do not differ between open versus laparoscopic prostatectomy
• Food supplement hinders prostate cancer cell growth in low-risk patients
• BMD plus clinical factors capture more breast cancer patients with fracture risk

Obesity impacting stroke incidence, mortality in China Posted: 25 Feb 2010 04:00 PM PST The rising prevalence of obesity in the Chinese population is increasing people's risk for suffering and dying of a stroke, shows a large prospective study.

Eosinophilic bronchitis ‘does not respond to bronchial challenge’ Posted: 25 Feb 2010 04:00 PM PST The airways of patients with eosinophilic bronchitis do not respond to direct or indirect bronchial challenge, study results show.

FeNO may predict treatment response in COPD exacerbations Posted: 25 Feb 2010 04:00 PM PST Fractional exhaled nitric oxide levels may help predict treatment response in chronic obstructive pulmonary disease patients who have been admitted to hospital for an exacerbation, say Hungarian researchers.

<i>NPSR1</i> gene link to asthma and atopy confirmed Posted: 25 Feb 2010 04:00 PM PST Study results confirm a link between variants of the neuropeptide S receptor 1 gene (NPSR1) and the development of asthma and atopy, particularly early-onset asthma.

Sleep efficiency and variability important bipolar treatment targets Posted: 25 Feb 2010 04:00 PM PST Sleep disturbance between episodes of bipolar disorder can affect illness course and may therefore be an important intervention target, say researchers.

Near-infrared spectroscopy helps identify schizophrenia patients Posted: 25 Feb 2010 04:00 PM PST Near-infrared spectroscopy measurements of prefrontal cortex activation could be used to differentiate patients with schizophrenia from healthy individuals, suggests research.

Incidental findings frequent with MRI for Crohn's disease Posted: 25 Feb 2010 04:00 PM PST Magnetic resonance imaging enterography in patients with known or suspected Crohn's disease commonly reveals incidental findings, research shows.

Clotting factors linked to vascular dementia Posted: 24 Feb 2010 04:00 PM PST A long-term prospective study of UK men has shown that hemostatic rather than inflammatory markers predict cognitive impairment and vascular dementia.

Prostate-specific antigen isoform p2PSA aids prostate cancer detection Posted: 24 Feb 2010 04:00 PM PST The diagnostic accuracy of prostate cancer detection could be improved by using prostate-specific antigen isoform p2PSA in combination with total PSA and free PSA, researchers report.

Prostate-specific antigen isoform p2PSA aids prostate cancer detection Posted: 24 Feb 2010 04:00 PM PST The diagnostic accuracy of prostate cancer detection could be improved by using prostate-specific antigen isoform p2PSA in combination with total PSA and free PSA, researchers report.

Recommendations for management of sentinal node micrometastases ignored Posted: 24 Feb 2010 04:00 PM PST Axillary lymph node dissection is underused in patients with sentinel node micrometastases from breast cancer, according to US researchers.

Coffee consumption reduces inflammation and increases HDL cholesterol Posted: 24 Feb 2010 04:00 PM PST Increasing coffee consumption reduces inflammatory markers and increases high-density lipoprotein cholesterol and adiponectin concentrations, report researchers.

<i>APOA</i> gene polymorphisms influence effect of dietary fat on LDL particle size Posted: 24 Feb 2010 04:00 PM PST Certain eating patterns may be more beneficial than others at increasing low-density lipoprotein particle size in people with particular apolipoprotein genotypes, a study indicates.

VLDL cholesterol predicts coronary risk in Chinese population Posted: 24 Feb 2010 04:00 PM PST Elevated levels of very-low-density lipoprotein cholesterol increase the risk for coronary heart disease in Chinese people, a large study has found.

Coffee consumption reduces inflammation and increases HDL cholesterol Posted: 24 Feb 2010 04:00 PM PST Increasing coffee consumption reduces inflammatory markers and increases high-density lipoprotein cholesterol and adiponectin concentrations, report researchers.

Women with GDM have increased risk for developing Type 2 diabetes Posted: 24 Feb 2010 04:00 PM PST Women who have gestational diabetes mellitus have substantially increased long-term risk for developing Type 2 diabetes after giving birth, show study results.

ICTUS 5-year data show no benefit of early invasive strategy Posted: 24 Feb 2010 04:00 PM PST Five-year follow-up data from the ICTUS trial found no long-term benefit of an early invasive strategy in reducing death or myocardial infarction in patients with non-ST-segment elevation acute coronary syndrome and elevated troponin T.

Femoral vascular closure device linked to reduced major access site bleeding Posted: 24 Feb 2010 04:00 PM PST Use of a vascular closure device is associated with a reduced risk for major access site bleeding in patients with acute coronary syndromes undergoing angiography with or without percutaneous coronary intervention by the femoral approach, shows a post-hoc subgroup analysis of ACUITY.

Recommendations for management of sentinal node micrometastases ignored Posted: 24 Feb 2010 04:00 PM PST Axillary lymph node dissection is underused in patients with sentinel node micrometastases from breast cancer, according to US researchers.

TIMP-3 shows potential as gene therapy for prostate cancer Posted: 23 Feb 2010 04:00 PM PST Researchers have discovered a potential new gene therapy for prostate cancer in the form of tissue inhibitor of metalloproteinase-3.

Prostate cancer detection rate high with transperineal template-guided mapping Posted: 23 Feb 2010 04:00 PM PST Transperineal template-guided mapping biopsy improves rates of prostate cancer detection at first and repeat biopsy, compared with the standard transrectal ultrasound approach, researchers report.

Migraine linked to reduced breast cancer risk Posted: 23 Feb 2010 04:00 PM PST A history of migraine is associated with a reduced risk for breast cancer, independent of nonsteroidal anti-inflammatory drug use, US research shows.

Metastasis after treatment for prostate cancer depends on disease risk Posted: 22 Feb 2010 04:00 PM PST Men with high-risk prostate cancer are less likely to experience metastatic disease progression if they are treated with radical prostatectomy compared with external beam radiotherapy, report researchers.

<i>p53</i> mutation links deprivation to poor breast cancer outcome Posted: 22 Feb 2010 04:00 PM PST A mutation in the p53 gene is associated with a worse outcome among the most socio-economically deprived patients with breast cancer, researchers in the UK show.

Postoperative outcomes do not differ between open versus laparoscopic prostatectomy Posted: 21 Feb 2010 04:00 PM PST Postoperative rates of mortality, morbidity, and requirement for additional treatment are similar between patients who undergo open radical prostatectomy and laparoscopic prostatectomy, report US researchers.

Food supplement hinders prostate cancer cell growth in low-risk patients Posted: 21 Feb 2010 04:00 PM PST Australian researchers have developed a dietary supplement which interrupts growth-promoting signaling pathways in prostate cancer cells.

BMD plus clinical factors capture more breast cancer patients with fracture risk Posted: 21 Feb 2010 04:00 PM PST Combining bone mineral density with clinical risk factors improves the identification of women with breast cancer who are at risk for fracture, German researchers report.

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