Medical News

ECM remodelling in distal lung of fatal asthma Posted: 18 May 2009 05:00 PM PDT The distal lung is a major site of extracellular matrix remodelling in patients with fatal asthma, research shows.

Anti-inflammatory mediator could explain chronic rhinosinusitis inflammation Posted: 18 May 2009 05:00 PM PDT Scientists in China have identified an anti-inflammatory mediator that they say is closely linked to the development of chronic rhinosinusitis and predicts outcomes following surgery for the condition.

Link between obesity, pro-inflammatory gene, and asthma Posted: 18 May 2009 05:00 PM PDT Obesity interacts with the tissue necrosis factor-α gene in the development of asthma, research shows.

Fronto-temporal dysregulation linked to memory deficits in BD Posted: 18 May 2009 05:00 PM PDT Study results suggest that disruption in the fronto-temporal neural circuitry may underlie memory difficulties frequently observed in patients with bipolar disorder.

Working memory–schizophrenia duration link ‘only in males’ Posted: 18 May 2009 05:00 PM PDT A longer duration of schizophrenia is associated with impaired prefrontal cortex activation in male, but not female, patients indicating working memory neural network deficits, UK study findings suggest.

‘Body, mind and spirit’ programme helps women with breast cancer cope Posted: 17 May 2009 05:00 PM PDT A programme designed to care for the whole person in 'body, mind and spirit' can help women with terminal breast cancer come to terms with their disease and improve their quality of life, US research suggests.

Uncontrolled high blood pressure increases diabetes risk Posted: 17 May 2009 05:00 PM PDT Patients with uncontrolled high blood pressure are around twice as likely to develop Type 2 diabetes as those with controlled hypertension, study results suggest.

Self-treatment programme benefits lung disease patients Posted: 17 May 2009 05:00 PM PDT A self-treatment programme that educates patients with chronic obstructive pulmonary disease about what to do during a symptom attack can reduce the duration of exacerbations as well as health care costs, researchers have found.

<i>Clostridium difficile</i> infection common in inflammatory bowel disease patients Posted: 17 May 2009 05:00 PM PDT Patients with inflammatory bowel disease who are in remission are more likely to be infected with the bug Clostridium difficile than healthy individuals, study results suggest.

Citrus pectin anti-thrombotic agent ’promising’ Posted: 17 May 2009 05:00 PM PDT A novel, chemically sulfated polysaccharide obtained from citrus pectin could be a potential alternative for heparin, Brazilian researchers report.

Thrombolysis in children ‘inconsistent’ Posted: 17 May 2009 05:00 PM PDT Thrombolysis treatment in children with acute arterial ischemic stroke often deviates from the adult guidelines, results of a multicenter cohort study show.

Axillary metastases rare following SNB in breast cancer patients Posted: 17 May 2009 05:00 PM PDT The rate of axillary metastases in breast cancer patients who do not receive axillary lymph node dissection after a negative sentinel node biopsy is lower than expected, large observational study shows.

<i>P3H2</i> and <i>P3H3</i> possible novel breast cancer suppressor genes Posted: 17 May 2009 05:00 PM PDT Expression of the prolyl 3-hydroxylase genes P3H2 and P3H3 is down-regulated via methylation in breast cancer cell lines and human primary tumors, a study shows.

Prostate biomarkers found in urine exosomes Posted: 17 May 2009 05:00 PM PDT Two prostate cancer biomarkers are found in exosomes from urine and may improve the diagnosis and monitoring of patients with prostate cancer, conclude researchers.

Postmenopausal DHEA treatment does not affect lipid profile, insulin sensitivity Posted: 17 May 2009 05:00 PM PDT Australian researchers have found that use of 50 mg oral dehydroepiandrosterone does not significantly alter lipid profile, insulin sensitivity, or adversely affect the endometrium in postmenopausal women.

EphA2 overexpression linked to poor outcome in endometrial cancer Posted: 17 May 2009 05:00 PM PDT Overexpression of the tyrosine kinase receptor EphA2 is associated with aggressive phenotypic features in endometrioid endometrial carcinoma and low estrogen and progesterone receptor expression, study results show.

CIN2/3 recurrence linked to initial CIN grade, treatment type, age Posted: 17 May 2009 05:00 PM PDT US researchers have found that risk for subsequent cervical intraepithelial neoplasia 2/3 after treatment is associated with initial CIN grade, treatment type, and age.

Suboptimal contraceptive use after childbirth common in obese women Posted: 17 May 2009 05:00 PM PDT US study results suggest that obese women are less likely to use effective contraceptive methods than overweight women a year after childbirth.

Obstetric outcomes improved by simple clinical intervention program Posted: 17 May 2009 05:00 PM PDT Maternal and newborn outcomes are significantly improved following implementation of a series of simple clinical interventions to improve safety, say researchers from Yale–New Haven Hospital's obstetrics unit.

Metoclopramide has better safety profile than droperidol for treating HG Posted: 17 May 2009 05:00 PM PDT A new protocol consisting of a combination of metoclopramide and diphenhydramine appears effective in improving symptoms of hyperemesis gravidarum, and is better tolerated than other treatments, say Canadian researchers.

Isoflavone-containing supplements vary greatly in content, have varied receptor activity Posted: 17 May 2009 05:00 PM PDT An Austrian study has found that the ingredients in commonly available red clover and soy preparations for treatment of menopausal symptoms vary greatly in isoflavone content, show large variations in receptor binding activity, and result in low receptor transactivation.

OC users have a reduced risk for colorectal cancer, especially with recent use Posted: 17 May 2009 05:00 PM PDT Results from a systematic review and meta-analysis indicate that women using oral contraceptives have a reduced risk for colorectal cancer.

High triglycerides, low HDL cholesterol independent risk factors for IHD Posted: 17 May 2009 05:00 PM PDT Elevated triglycerides and low high-density lipoprotein cholesterol levels are independent risk factors for ischemic heart disease in Korean men, show results from a prospective cohort study.

<i>LDLR</i> mutation type in children predicts later severity of FH Posted: 17 May 2009 05:00 PM PDT Children with familial hypercholesterolemia who have negative low-density lipoprotein receptor gene mutations have a more severe phenotype and are more likely to have relatives with premature coronary artery disease than those with LDLR-defective mutations, report researchers.

Survival with ICDs, CRT-Ds in contemporary practice better than in trials Posted: 17 May 2009 05:00 PM PDT Results from the ALTITUDE study revealed higher survival rates among patients with implantable cardioverter defibrillators or cardiac resynchronization therapy devices than previously reported in clinical trials.

Meal-time glucose excursions improved with three times daily BIAsp Posted: 17 May 2009 05:00 PM PDT A high-mix biphasic insulin aspart insulin three-times-daily regimen achieves lower blood glucose levels during the day for Type 2 diabetics than a twice-daily premix human insulin regimen, researchers report.

Insulin or TZ treatment linked to reduced coronary stenosis Posted: 17 May 2009 05:00 PM PDT Study results show that patients with Type 2 diabetes who are treated with insulin or a thiazolidinedione have fewer highly stenotic coronary artery lesions than those not treated with these drugs regardless of duration of diabetes, glycemic control, or other risk factors.

Survival with ICDs, CRT-Ds in contemporary practice better than in trials Posted: 17 May 2009 05:00 PM PDT Results from the ALTITUDE study revealed higher survival rates among patients with implantable cardioverter defibrillators or cardiac resynchronization therapy devices than previously reported in clinical trials.

Admission NT-proBNP prognostic in elderly with AMI Posted: 17 May 2009 05:00 PM PDT Admission N-terminal pro-brain natriuretic peptide levels retain their prognostic value in elderly people with acute myocardial infarction, despite being generally higher in older age groups, a study suggests.

Topical corticosteroids remain the short-term option for scalp psoriasis Posted: 30 Apr 2009 05:00 PM PDT Topical corticosteroids are the recommended short-term or intermittent treatment for scalp psoriasis, concludes The National Psoriasis Foundation Medical Board.

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