Medical News

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• Ion-channel protein plays role in inflammation and airway hyperreactivity
• Mouth taping fails to improve asthma symptoms
• Accuracy of quality of care measures differs in Medicaid asthma patients
• Gray matter deficits found in older bipolar disorder patients
• Circadian gene not linked to schizophrenia and mood disorders
• Reduced ALIC at diagnosis points to worse 1-year schizophrenia outcome
• Early-onset mental health disorders linked to non-completion of education
• Neuronal changes linked to psoriasis exacerbation
• Cancer risk may be increased in psoriasis patients
• Phototherapy regimens have differential impact on vitamin D
• Perceived negative attitude from others may be early psychosis sign
• Omega-3 and -6 oil asthma, allergy benefit in doubt
• Colorectal cancer more common in certain inflammatory bowel disease types
• Cancer survivors and physicians differ in healthcare expectations
• Junior MICU staff less likely to prescribe DVT prophylaxis
• Compression stockings do not reduce DVT risk after stroke
• PSA half time and doubling time predict metastatic prostate cancer outcomes
• Extra biopsy cores confirm predictive power of microfocal prostate cancer
• African–American women often refuse advanced breast cancer treatment
• PSA half time and doubling time predict metastatic prostate cancer outcomes
• Extra biopsy cores confirm predictive power of microfocal prostate cancer
• Resveratrol enhances cholesterol efflux through antioxidation
• High HDL cholesterol reduces risk for PCI-related MI
• No link between coffee drinking and CVD in men with Type 2 diabetes
• Glycated albumin, direct LDL cholesterol assays could improve glucose, lipid control assessment
• Heart failure risk increased by heart disease-linked chromosome variant
• Younger women with MI fare worse than young men
• African–American women often refuse advanced breast cancer treatment
• Updated prostate cancer failure criteria reduce false-positive rates
• Breast cancer survivors at same risk for CRC as general population
• Poor outcome for node-negative breast cancer patients who develop locoregional failure
• Errors on proton prostate cancer therapy ‘can be reduced to <2.5 mm’
• Death risk from advanced prostate cancer increased in younger men
• Raised isoprostane excretion increases risk for breast cancer in obese
• High rate of NICU, hospitalizations in ART twins
• Intravaginal DHEA effective treatment for postmenopausal sexual dysfunction
• Postmenopausal hormone therapy improves aerobic capacity
• Young esophageal cancer patients ‘most likely women’
• Women with psoriasis have increased risk for diabetes and hypertension

Ion-channel protein plays role in inflammation and airway hyperreactivity Posted: 28 May 2009 05:00 PM PDT US researchers have identified a pro-inflammatory ion-channel protein that plays a role in asthma.

Mouth taping fails to improve asthma symptoms Posted: 28 May 2009 05:00 PM PDT Taping closed the mouth to encourage breathing through the nose does not benefit patients with asthma, results from a randomized study published in the journal Respiratory Medicine show.

Accuracy of quality of care measures differs in Medicaid asthma patients Posted: 28 May 2009 05:00 PM PDT Measures for assessing the quality of asthma care differ in reliability both among themselves and when applied to Medicaid patients or those cared for privately, study findings show.

Gray matter deficits found in older bipolar disorder patients Posted: 28 May 2009 05:00 PM PDT Older bipolar disorder patients have inferior frontal lobe gray matter volume deficits, including in areas associated with the anterior limbic network, US researchers have discovered.

Circadian gene not linked to schizophrenia and mood disorders Posted: 28 May 2009 05:00 PM PDT It appears that variations in the CLOCK gene do not play a major role in the development of schizophrenia, bipolar disorder, or major depressive disorder, conclude Japanese investigators.

Reduced ALIC at diagnosis points to worse 1-year schizophrenia outcome Posted: 28 May 2009 05:00 PM PDT First-episode schizophrenia patients are more likely to have poor 1-year outcomes if they have a reduced area of the anterior limb of the internal capsule, potentially indicating fronto-thalamic connectivity disturbance, say German scientists.

Early-onset mental health disorders linked to non-completion of education Posted: 28 May 2009 05:00 PM PDT People who develop mental health disorders in childhood or adolescence are less likely to complete their education than mentally healthy people, and this association is true for patients living in both high- and middle- or low-income countries, research shows.

Neuronal changes linked to psoriasis exacerbation Posted: 28 May 2009 05:00 PM PDT Neurogenic inflammation is involved in psoriasis, say researchers who found a down-regulation of innervation during psoriasis exacerbation.

Cancer risk may be increased in psoriasis patients Posted: 28 May 2009 05:00 PM PDT People with psoriasis may face a higher-than-expected risk of developing certain cancers, research suggests.

Phototherapy regimens have differential impact on vitamin D Posted: 28 May 2009 05:00 PM PDT In patients with psoriasis, blood levels of vitamin D increase less with narrowband than with broadband radiation, despite both treatments being effective in improving symptoms.

Perceived negative attitude from others may be early psychosis sign Posted: 27 May 2009 05:00 PM PDT Believing that other people feel negatively towards you could be an early sign of psychosis, an international team of researchers suggests.

Omega-3 and -6 oil asthma, allergy benefit in doubt Posted: 27 May 2009 05:00 PM PDT Oils rich in omega-3 and -6 fatty acids are unlikely to play important roles in preventing common allergic disorders such as eczema and asthma, a review of studies suggests.

Colorectal cancer more common in certain inflammatory bowel disease types Posted: 27 May 2009 05:00 PM PDT The risk of developing colorectal cancer could vary according to the type of inflammatory bowel disease a person has, a Chinese study has revealed.

Cancer survivors and physicians differ in healthcare expectations Posted: 27 May 2009 05:00 PM PDT Patients differ to physicians in their expectations as to who holds responsibility for their healthcare after surviving treatment for cancer, a study suggests.

Junior MICU staff less likely to prescribe DVT prophylaxis Posted: 27 May 2009 05:00 PM PDT The degree of compliance to prophylaxis for deep vein thrombosis is higher in patients admitted to a medical intensive care unit by more senior residents and in those with a lower risk for deep vein thrombosis, research shows.

Compression stockings do not reduce DVT risk after stroke Posted: 27 May 2009 05:00 PM PDT Results from the first CLOTS trial provide no evidence to support the routine use of graduated compression stockings in patients with stroke.

PSA half time and doubling time predict metastatic prostate cancer outcomes Posted: 27 May 2009 05:00 PM PDT Prostate-specific antigen rises after androgen deprivation therapy and death in metastatic prostate cancer are predicted by the half-time and post-nadir doubling time of antigen levels, Korean study findings suggest.

Extra biopsy cores confirm predictive power of microfocal prostate cancer Posted: 27 May 2009 05:00 PM PDT Significant prostate cancer may be distinguished from insignificant cancers by performing additional cores in the case of microfocal cancer on sextant prostate biopsies, conclude US and French researchers.

African–American women often refuse advanced breast cancer treatment Posted: 27 May 2009 05:00 PM PDT A high proportion of African–American women with advanced breast cancer refuse chemotherapy and radiotherapy for advanced breast cancer, a US retrospective study shows.

PSA half time and doubling time predict metastatic prostate cancer outcomes Posted: 27 May 2009 05:00 PM PDT Prostate-specific antigen rises after androgen deprivation therapy and death in metastatic prostate cancer are predicted by the half-time and post-nadir doubling time of antigen levels, Korean study findings suggest.

Extra biopsy cores confirm predictive power of microfocal prostate cancer Posted: 27 May 2009 05:00 PM PDT Significant prostate cancer may be distinguished from insignificant cancers by performing additional cores in the case of microfocal cancer on sextant prostate biopsies, conclude US and French researchers.

Resveratrol enhances cholesterol efflux through antioxidation Posted: 27 May 2009 05:00 PM PDT The polyphenol resveratrol contained in red wine has a natural antioxidant capacity that appears to enhance cholesterol efflux, say researchers.

High HDL cholesterol reduces risk for PCI-related MI Posted: 27 May 2009 05:00 PM PDT Patients undergoing elective percutaneous coronary intervention with higher levels of high-density lipoprotein cholesterol have a substantially reduced risk for PCI-related myocardial infarction than those with lower levels, show results published in the European Heart Journal.

No link between coffee drinking and CVD in men with Type 2 diabetes Posted: 27 May 2009 05:00 PM PDT Regular consumption of coffee is not associated with increased risk for cardiovascular disease or mortality in men with Type 2 diabetes, report investigators in the journal Diabetes Care.

Glycated albumin, direct LDL cholesterol assays could improve glucose, lipid control assessment Posted: 27 May 2009 05:00 PM PDT Glycated albumin compares well with glycated hemoglobin as a marker of diabetes control, and direct is more accurate than calculated low-density lipoprotein cholesterol, in Type 2 diabetes patients with hypertriglyceridemia, new research shows.

Heart failure risk increased by heart disease-linked chromosome variant Posted: 27 May 2009 05:00 PM PDT A variant on chromosome 9p21 that is known to increase coronary heart disease risk also increases heart failure risk among White people, say US scientists who found only weak associations with other atherosclerotic outcomes.

Younger women with MI fare worse than young men Posted: 27 May 2009 05:00 PM PDT Gender-related differences in short-term mortality after myocardial infarction are driven primarily by worse outcomes in younger women, US research shows.

African–American women often refuse advanced breast cancer treatment Posted: 27 May 2009 05:00 PM PDT A high proportion of African–American women with advanced breast cancer refuse chemotherapy and radiotherapy for advanced breast cancer, a US retrospective study shows.

Updated prostate cancer failure criteria reduce false-positive rates Posted: 26 May 2009 05:00 PM PDT Half of the false-positive biochemical failures identified after radiotherapy with or without neoadjuvant androgen deprivation for prostate cancer can be prevented by using updated definitions, say scientists.

Breast cancer survivors at same risk for CRC as general population Posted: 26 May 2009 05:00 PM PDT Women diagnosed with breast cancer do not have an increased risk for right-sided colorectal cancer or CRC in general, a Canadian study shows.

Poor outcome for node-negative breast cancer patients who develop locoregional failure Posted: 26 May 2009 05:00 PM PDT Women with lymph node-negative breast cancer who develop locoregional failure after breast-conserving surgery are at increased risk for distant disease and death, study analysis shows.

Errors on proton prostate cancer therapy ‘can be reduced to <2.5 mm’ Posted: 25 May 2009 05:00 PM PDT An action level image-guided radiation therapy process allows all errors in final prostate position for proton therapy to be limited to less than 2.5 mm, conclude US investigators.

Death risk from advanced prostate cancer increased in younger men Posted: 25 May 2009 05:00 PM PDT Although younger prostate cancer patients have better overall outcomes than their older counterparts, those with advanced disease have a significantly increased risk for death, US study findings indicate.

Raised isoprostane excretion increases risk for breast cancer in obese Posted: 25 May 2009 05:00 PM PDT Urinary excretion of the isoprostane 15-F2t-isoprostane and its metabolite 2,3-dinor-5,6-dihydro-15-F2t-IsoP is positively associated with breast cancer risk only in overweight women, a Chinese study shows.

High rate of NICU, hospitalizations in ART twins Posted: 24 May 2009 05:00 PM PDT Study results suggest that twins conceived using assisted reproductive technology are more likely than spontaneously conceived twins to be admitted to a neonatal intensive care unit and be hospitalized within the first 3 years of life.

Intravaginal DHEA effective treatment for postmenopausal sexual dysfunction Posted: 24 May 2009 05:00 PM PDT Combined androgenic/estrogenic stimulation in the three layers of the vagina through local transformation of dehydroepiandrosterone exerts important beneficial effects on sexual function in postmenopausal women without systemic action on the brain and other extravaginal tissue, phase III clinical trial results suggest.

Postmenopausal hormone therapy improves aerobic capacity Posted: 24 May 2009 05:00 PM PDT In the absence of hormone replacement therapy, periods of amenorrhea lasting more than 10 years worsen the maximum oxygen intake in obese and sarcopenic postmenopausal women, suggest study results.

Young esophageal cancer patients ‘most likely women’ Posted: 03 May 2009 05:00 PM PDT Young patients with esophageal cancer have squamous cell carcinoma as the predominant histology and are more likely to be women than men, a Turkish study suggests.

Women with psoriasis have increased risk for diabetes and hypertension Posted: 22 Apr 2009 05:00 PM PDT Women with the skin condition psoriasis have an increased risk for diabetes and hypertension, report researchers from the Nurses' Health Study.

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