Medical News

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• Transcription factor mutations triple childhood asthma risk
• Occupational exposure accounts for 18% of adult asthma cases
• Anti-cholinergic benefits a third of severe asthmatics
• Neuroanatomic differences exist between intermediate-, early-onset BD
• Insular cortex deficits linked to psychosis development
• Common virus linked with high blood pressure
• Clue to eczema-asthma link revealed
• Genetic tests for breast or ovarian cancer underused
• Depression and migraines may share genes
• Emergency medical dispatch algorithm for stroke ‘needs strengthening’
• Breast cancer survivors at same risk for CRC as general population
• Poor outcome for node-negative breast cancer patients who develop locoregional failure
• Updated prostate cancer failure criteria reduce false-positive rates
• Aggressive lipid management effective and well tolerated by elderly
• Moderate alcohol consumption increases adiponectin
• Vildagliptin as effective as metformin in elderly Type 2 diabetes patients
• Fenofibrate reduces risk for microvascular disease related amputation
• Genetic link between periodontitis and CHD identified
• Prior polyvascular disease is a risk factor for ischemic events in ACS
• Differences found between pre-, postmenopausal ovarian cancer
• Vardenafil plus sertraline effective for temporary erectile dysfunction in ART
• Ovarian granulosa cell ERK1/2 disruption interrupts fertility
• Symptom scale reflects GERD endoscopic severity

Transcription factor mutations triple childhood asthma risk Posted: 27 May 2009 05:00 PM PDT Scientists have identified two polymorphisms of the T-cell-specific T-box transcription factor gene that are closely involved in the development of asthma in children.

Occupational exposure accounts for 18% of adult asthma cases Posted: 27 May 2009 05:00 PM PDT Physicians should routinely consider occupational background when assessing patients for asthma, recommend researchers who found that almost 18% of asthma in those of working age is caused by occupational exposure.

Anti-cholinergic benefits a third of severe asthmatics Posted: 27 May 2009 05:00 PM PDT Up to a third of patients with severe asthma that persists despite conventional treatment would benefit from also taking an anti-cholinergic drug, say researchers.

Neuroanatomic differences exist between intermediate-, early-onset BD Posted: 27 May 2009 05:00 PM PDT Researchers have found the first evidence for a neuroanatomic difference between intermediate-onset and early-onset bipolar disorder in the form of sulcal deviations.

Insular cortex deficits linked to psychosis development Posted: 27 May 2009 05:00 PM PDT Researchers have found prominent gray matter changes in the insular cortex subregion in ultra-high-risk neuroleptic-naïve individuals who later developed psychosis.

Common virus linked with high blood pressure Posted: 26 May 2009 05:00 PM PDT A common virus carried by most people could be a cause of high blood pressure, a study indicates.

Clue to eczema-asthma link revealed Posted: 26 May 2009 05:00 PM PDT US researchers may have discovered a clue as to why children with eczema often develop asthma in later life.

Genetic tests for breast or ovarian cancer underused Posted: 26 May 2009 05:00 PM PDT Few women at risk of hereditary breast or ovarian cancer have talked about genetic testing with their physician, US research suggests, despite guidelines recommending these discussions.

Depression and migraines may share genes Posted: 26 May 2009 05:00 PM PDT Depression and migraine headaches may have genetic factors in common, a study of twins has revealed.

Emergency medical dispatch algorithm for stroke ‘needs strengthening’ Posted: 26 May 2009 05:00 PM PDT Less than half of all patients with acute stroke are identified by telephone triage on the initial emergency call to the ambulance service, and less than a quarter receives the highest priority of ambulance response, a UK study has found.

Breast cancer survivors at same risk for CRC as general population Posted: 26 May 2009 05:00 PM PDT Women diagnosed with breast cancer do not have an increased risk for right-sided colorectal cancer or CRC in general, a Canadian study shows.

Poor outcome for node-negative breast cancer patients who develop locoregional failure Posted: 26 May 2009 05:00 PM PDT Women with lymph node-negative breast cancer who develop locoregional failure after breast-conserving surgery are at increased risk for distant disease and death, study analysis shows.

Updated prostate cancer failure criteria reduce false-positive rates Posted: 26 May 2009 05:00 PM PDT Half of the false-positive biochemical failures identified after radiotherapy with or without neoadjuvant androgen deprivation for prostate cancer can be prevented by using updated definitions, say scientists.

Aggressive lipid management effective and well tolerated by elderly Posted: 26 May 2009 05:00 PM PDT Results from the ALLIANCE study show that aggressive lipid management with atorvastatin is effective at reducing adverse cardiovascular events and well tolerated in elderly patients.

Moderate alcohol consumption increases adiponectin Posted: 26 May 2009 05:00 PM PDT Moderate alcohol consumption significantly increases adiponectin levels, but in a gender-specific manner dependent on the type of beverage consumed, report researchers.

Vildagliptin as effective as metformin in elderly Type 2 diabetes patients Posted: 26 May 2009 05:00 PM PDT Vildagliptin provides similar glycated hemoglobin reductions to metformin but with superior gastrointestinal tolerability in drug-naïve elderly patients with Type 2 diabetes, research shows.

Fenofibrate reduces risk for microvascular disease related amputation Posted: 26 May 2009 05:00 PM PDT Treatment of patients with Type 2 diabetes without known large-vessel disease with fenofibrate significantly reduces their risk for amputation events, report researchers from the FIELD study.

Genetic link between periodontitis and CHD identified Posted: 26 May 2009 05:00 PM PDT Researchers have identified shared susceptibility loci for coronary heart disease and periodontitis, which they say confirms a strong genetic link between the two diseases.

Prior polyvascular disease is a risk factor for ischemic events in ACS Posted: 26 May 2009 05:00 PM PDT Prior polyvascular disease increases the risk for in-hospital adverse events in patients with acute coronary syndrome, US research shows.

Differences found between pre-, postmenopausal ovarian cancer Posted: 24 May 2009 05:00 PM PDT Research presented at the 8th European Congress on Menopause suggests that ovarian cancer in postmenopausal women occurs at a more advanced stage than in premenopausal women, with differences seen in histological subtypes.

Vardenafil plus sertraline effective for temporary erectile dysfunction in ART Posted: 24 May 2009 05:00 PM PDT Results from a five-patient case report suggest that the combined protocol of vardenafil plus sertraline is an effective and well-tolerated treatment for temporary erectile dysfunction during assisted reproductive technologies.

Ovarian granulosa cell ERK1/2 disruption interrupts fertility Posted: 24 May 2009 05:00 PM PDT US researchers have found that disruption of the extracellular signal–regulated kinases 1 and 2 interferes with the ability of luteinizing hormone to induce genes that play a key role in ovarian function and female fertility.

Symptom scale reflects GERD endoscopic severity Posted: 03 May 2009 05:00 PM PDT Japanese researchers have identified a symptom assessment scale that reflects the endoscopic severity of gastroesophageal reflux disease.

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