Medical News

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• Natural history of acute COPD exacerbations defined
• ‘Atopic march’ from dermatitis to asthma could be halted
• Bronchial thermoplasty improves quality of life, reduces asthma exacerbations
• Hypomanic symptoms common in the immediate postpartum period
• Reduced gray matter volume occurs early in schizophrenia
• Childhood tobacco smoke exposure linked to emphysema in later life
• Early-onset mental health disorders increase risk of poor education attainment
• Intensive control of blood glucose lowers heart disease risk in diabetes patients
• Statins may reduce risk of second stroke
• No role for prognostic markers in hemodynamically stable acute PE
• Novel algorithm detects AF in stroke patients
• Raised isoprostane excretion increases risk for breast cancer in obese
• Errors on proton prostate cancer therapy ‘can be reduced to <2.5 mm’
• Death risk from advanced prostate cancer increased in younger men
• Cetilistat has similar weight loss benefits to orlistat but is better tolerated
• Fenofibrate-induced HDL effect may be influenced by homocysteine increase
• Novel DPP-4 inhibitor linagliptin shows early promise
• Cetilistat has similar weight loss benefits to orlistat but is better tolerated
• Metabolic syndrome common in Japanese children with Type 2 diabetes
• Bone marrow cell therapy shows promise in myocardial ischemia
• Cytomegalovirus infection increases arterial blood pressure
• Clinical information better than BP alone to predict future hypertension

Natural history of acute COPD exacerbations defined Posted: 26 May 2009 05:00 PM PDT Treating an acute exacerbation of chronic obstructive pulmonary disease with oral corticosteroids reduces neutrophil inflammation and improves anti-protease functioning within just 48 hours, study findings show.

‘Atopic march’ from dermatitis to asthma could be halted Posted: 26 May 2009 05:00 PM PDT Scientists have identified the changes that may explain why atopic dermatitis often leads to asthma as well as potential ways to prevent this "atopic march."

Bronchial thermoplasty improves quality of life, reduces asthma exacerbations Posted: 26 May 2009 05:00 PM PDT The use of radiofrequency ablation in individuals with severe, symptomatic asthma improves quality of life and reduces exacerbations compared with a sham procedure, US research shows.

Hypomanic symptoms common in the immediate postpartum period Posted: 26 May 2009 05:00 PM PDT Study results suggest that hypomanic symptoms are common in the postpartum period and are significantly increased from antenatal rates in the general population.

Reduced gray matter volume occurs early in schizophrenia Posted: 26 May 2009 05:00 PM PDT Study results show patients with schizophrenia have a reduced gray matter volume early in their illness compared with healthy individuals, although this difference diminishes with age.

Childhood tobacco smoke exposure linked to emphysema in later life Posted: 25 May 2009 05:00 PM PDT Children who are regularly exposed to tobacco smoke may face an increased risk of lung damage and emphysema in later life, study results suggest.

Early-onset mental health disorders increase risk of poor education attainment Posted: 25 May 2009 05:00 PM PDT People who develop mental health disorders in childhood or adolescence are less likely to complete their education than mentally healthy people, irrespective of whether patients live in high- or middle- and low-income countries, research shows.

Intensive control of blood glucose lowers heart disease risk in diabetes patients Posted: 25 May 2009 05:00 PM PDT Study findings show that intensively lowering blood glucose levels in patients with Type 2 diabetes significantly reduces their risk of heart attacks and other coronary heart disease-related problems compared with standard glucose control.

Statins may reduce risk of second stroke Posted: 25 May 2009 05:00 PM PDT Patients who have suffered a stroke are less likely to experience another stroke if they take cholesterol-lowering drugs called statins, research suggests.

No role for prognostic markers in hemodynamically stable acute PE Posted: 25 May 2009 05:00 PM PDT Commonly used prognostic markers do not predict in-hospital pulmonary embolism-related adverse events in normotensive patients treated with conventional anticoagulation, study findings indicate.

Novel algorithm detects AF in stroke patients Posted: 25 May 2009 05:00 PM PDT A novel diagnostic algorithm developed by French researchers aids the detection of atrial fibrillation in the secondary prevention of ischemic stroke.

Raised isoprostane excretion increases risk for breast cancer in obese Posted: 25 May 2009 05:00 PM PDT Urinary excretion of the isoprostane 15-F2t-isoprostane and its metabolite 2,3-dinor-5,6-dihydro-15-F2t-IsoP is positively associated with breast cancer risk only in overweight women, a Chinese study shows.

Errors on proton prostate cancer therapy ‘can be reduced to <2.5 mm’ Posted: 25 May 2009 05:00 PM PDT An action level image-guided radiation therapy process allows all errors in final prostate position for proton therapy to be limited to less than 2.5 mm, conclude US investigators.

Death risk from advanced prostate cancer increased in younger men Posted: 25 May 2009 05:00 PM PDT Although younger prostate cancer patients have better overall outcomes than their older counterparts, those with advanced disease have a significantly increased risk for death, US study findings indicate.

Cetilistat has similar weight loss benefits to orlistat but is better tolerated Posted: 25 May 2009 05:00 PM PDT The weight-loss drug cetilistat improves weight and glycemic control to the same degree as orlistat among obese metformin-treated individuals with Type 2 diabetes, but is better tolerated by patients, report researchers.

Fenofibrate-induced HDL effect may be influenced by homocysteine increase Posted: 25 May 2009 05:00 PM PDT Results from the FIELD study show that patients with greater fenofibrate-mediated increases in homocysteine are likely to have smaller increases in high-density lipoprotein cholesterol, perhaps explaining the variable response to fenofibrate in different patients.

Novel DPP-4 inhibitor linagliptin shows early promise Posted: 25 May 2009 05:00 PM PDT The first dose-ranging study of linagliptin in male patients with Type 2 diabetes demonstrates significant improvement in glucose parameters and good tolerability, report researchers.

Cetilistat has similar weight loss benefits to orlistat but is better tolerated Posted: 25 May 2009 05:00 PM PDT The weight-loss drug cetilistat improves weight and glycemic control to the same degree as orlistat among obese metformin-treated individuals with Type 2 diabetes, but is better tolerated by patients, report researchers.

Metabolic syndrome common in Japanese children with Type 2 diabetes Posted: 25 May 2009 05:00 PM PDT Japanese researchers report a high prevalence of metabolic syndrome components in addition to hyperglycemia in children at the time of Type 2 diabetes diagnosis.

Bone marrow cell therapy shows promise in myocardial ischemia Posted: 25 May 2009 05:00 PM PDT Intramyocardial injection of bone marrow cells resulted in a modest but significant improvement in myocardial perfusion as well as improvements in left ventricular (LV) function and angina symptoms in patients with chronic myocardial ischemia, a small, short-term phase II trial shows.

Cytomegalovirus infection increases arterial blood pressure Posted: 25 May 2009 05:00 PM PDT Cytomegalovirus infection is a risk factor for increased blood pressure, US research suggests.

Clinical information better than BP alone to predict future hypertension Posted: 22 Apr 2009 05:00 PM PDT Use of a model based on readily available clinical information is better able to predict the development of hypertension than one based on blood pressure alone, US researchers report.

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