Medical News

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• Airway epithelial changes evident in asthmatic smokers
• New model to predict positive sputum cultures in COPD
• Home visits improve childhood asthma control
• Auditory attention independent of mood, medication, psychosis in BD
• Depression during psychosis prodrome predicts depression, self-harm
• Family history, atopy demonstrate genetic risk factors for pediatric IBD
• Rapid and complete CUS feasible and comparable for DVT diagnosis
• Mismatch-based delayed thrombolysis attractive but not yet ready for routine care
• Anti-HER2 therapy ‘should be considered’ for HER2-positive, node negative breast cancer
• PSA velocity able to identify clinically significant disease
• Researchers call for standardized reporting of prostate surgery complications
• Stanol ester consumption reduces CVD risk in dyslipidemic individuals
• Replacement of trans fatty acids with stearic acid benefits CV health
• Diabetes screening ‘does not give false reassurance about future risk’
• Nocturnal intermittent hypoxia increases risk for Type 2 diabetes
• ICD benefit in SCD-HeFT driven by ventricular tachyarrhythmia mortality reduction
• Multiparametric echo strategy may improve ability to predict CRT response

Airway epithelial changes evident in asthmatic smokers Posted: 01 Dec 2009 04:00 PM PST Asthma patients who smoke show evidence of abnormal epithelial changes, researchers have found.

New model to predict positive sputum cultures in COPD Posted: 01 Dec 2009 04:00 PM PST Clinical markers of chronic obstructive pulmonary disease determined during an exacerbation of the disease predict the isolation of bacteria from the sputum, results show.

Home visits improve childhood asthma control Posted: 01 Dec 2009 04:00 PM PST Home visits by an asthma specialist can help improve medication adherence, reduce symptom frequency and cut emergency department visits among inner-city children with the respiratory condition, US research shows.

Auditory attention independent of mood, medication, psychosis in BD Posted: 01 Dec 2009 04:00 PM PST Study findings suggest that disrupted auditory attention is observed in bipolar disorder patients independent of their mood state, medication status, or history of psychotic features, but may be influenced by the presence of a comorbid anxiety disorder.

Depression during psychosis prodrome predicts depression, self-harm Posted: 01 Dec 2009 04:00 PM PST Study findings suggest that comorbid depression during the prodromal phase of psychosis is a key contributor to the development of future depression and suicidal thinking.

Family history, atopy demonstrate genetic risk factors for pediatric IBD Posted: 01 Dec 2009 04:00 PM PST Pediatric inflammatory bowel disease (IBD) is predicted by a family history of the disease and childhood atopy, Scottish research suggests.

Rapid and complete CUS feasible and comparable for DVT diagnosis Posted: 30 Nov 2009 04:00 PM PST Researchers say that deep venous thrombosis can be efficiently diagnosed using a clinical decision rule, a D-dimer test and a either a rapid or complete compression ultrasound examination.

Mismatch-based delayed thrombolysis attractive but not yet ready for routine care Posted: 30 Nov 2009 04:00 PM PST The use of mismatch imaging to identify patients who will benefit from delayed thrombolysis is a promising strategy but requires validation in a phase III trial, say the authors of a meta-analysis.

Anti-HER2 therapy ‘should be considered’ for HER2-positive, node negative breast cancer Posted: 30 Nov 2009 04:00 PM PST Patients with small, node-negative, human epidermal growth factor receptor 2–positive breast cancer have a significant risk for relapse and should be considered for systemic, anti-HER2, adjuvant therapy, say researchers.

PSA velocity able to identify clinically significant disease Posted: 30 Nov 2009 04:00 PM PST Prostate-specific antigen velocity may be a useful addition to prostate cancer screening protocols in the accurate identification of patients with clinically significant disease, study findings show.

Researchers call for standardized reporting of prostate surgery complications Posted: 30 Nov 2009 04:00 PM PST Complications associated with prostate surgery should be reported in a standardized manner, state researchers.

Stanol ester consumption reduces CVD risk in dyslipidemic individuals Posted: 30 Nov 2009 04:00 PM PST Mildly hypercholesterolemic individuals who consume a spread rich in plant stanol esters show a significant reduction in lipid levels and cardiovascular risk, report investigators.

Replacement of trans fatty acids with stearic acid benefits CV health Posted: 30 Nov 2009 04:00 PM PST Results from a systematic review show that replacing trans fats with high stearic acid soybean oil has beneficial effects on lipid levels and therefore cardiovascular health.

Diabetes screening ‘does not give false reassurance about future risk’ Posted: 30 Nov 2009 04:00 PM PST A negative result from diabetes screening does not give patients false reassurance about their future risk for developing the disease, analysis of data from over 5000 patients shows.

Nocturnal intermittent hypoxia increases risk for Type 2 diabetes Posted: 30 Nov 2009 04:00 PM PST Results from a Japanese study show that nocturnal intermittent hypoxia, a surrogate marker of obstructive sleep apnea, increases the risk for developing Type 2 diabetes.

ICD benefit in SCD-HeFT driven by ventricular tachyarrhythmia mortality reduction Posted: 30 Nov 2009 04:00 PM PST A substudy of SCD-HeFT demonstrates that implantable cardioverter defibrillator therapy reduced cardiac mortality through a reduction in presumed ventricular tachyarrhythmias, having no impact on heart failure mortality.

Multiparametric echo strategy may improve ability to predict CRT response Posted: 30 Nov 2009 04:00 PM PST A multiparametric echocardiographic strategy is better at identifying heart failure patients likely to respond to cardiac resynchronization therapy than existing single parametric approaches, a study indicates.

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