Medical News

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• Risk of suicide persists in first-episode psychosis patients
• Recollection shows endophenotype potential in schizophrenia
• Prefrontal dysfunction common to ADHD and pediatric bipolar disorder
• Negative specific memory recall increased with hypomania risk
• Schizophrenia gray matter reductions ‘in addition to genetic risk changes’
• Subthreshold bipolar disorder common in major depression
• Apathy linked to poor functioning in first-episode psychosis
• Left amygdala response to facial emotion highlights bipolar depression

Risk of suicide persists in first-episode psychosis patients Posted: 23 Dec 2009 04:00 PM PST First-episode psychosis (FEP) patients have a high risk for suicide attempt that remains prevalent for at least 7 years and is predicted by previous self-harm, Australian study findings indicate.

Recollection shows endophenotype potential in schizophrenia Posted: 23 Dec 2009 04:00 PM PST Schizophrenia patients show memory deficits in both familiarity and recollection whereas their parents have deficits only in recollection, the results of a Canadian study indicate.

Prefrontal dysfunction common to ADHD and pediatric bipolar disorder Posted: 23 Dec 2009 04:00 PM PST Both attention deficit hyperactivity disorder and pediatric bipolar disorder patients exhibit prefrontal dysfunction, although it is more extensive in the former group, conclude US researchers.

Negative specific memory recall increased with hypomania risk Posted: 23 Dec 2009 04:00 PM PST Individuals at high risk for bipolar hypomania have increased access to negative specific memories, say UK researchers who suggest that encouraging positive memory recall may benefit bipolar disorder patients.

Schizophrenia gray matter reductions ‘in addition to genetic risk changes’ Posted: 22 Dec 2009 04:00 PM PST Schizophrenia patients have reductions in gray matter volume that occur in addition to those associated with genetic risk for the disorder, say scientists who concede the reasons for the reductions are unclear.

Subthreshold bipolar disorder common in major depression Posted: 22 Dec 2009 04:00 PM PST Major depressive disorder is a heterogeneous disorder that contains a substantial proportion of patients with clinically significant subthreshold bipolar disorder, study results indicate.

Apathy linked to poor functioning in first-episode psychosis Posted: 21 Dec 2009 04:00 PM PST Poor functioning in patients with first-episode psychosis (FEP) is associated with the negative subsyndrome of apathy, say researchers who recommend including negative symptoms in early detection strategies.

Left amygdala response to facial emotion highlights bipolar depression Posted: 21 Dec 2009 04:00 PM PST Increased left amygdala activity in response to mild sad and neutral faces appears to be a marker for depression in bipolar disorder but not major depressive disorder (MDD), concludes a team of international scientists.

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