Thursday, December 17, 2009

Medical News

Medical News


Mean platelet volume may predict VTE risk

Posted: 17 Dec 2009 04:00 PM PST

Norwegian researchers have found that a high mean platelet volume increases the risk for venous thromboembolism.

Elinogrel promising adjunct to PCI for STEMI

Posted: 17 Dec 2009 04:00 PM PST

Results of pilot study show that elinogrel, a novel P2Y12 ADP-receptor antagonist, is a well-tolerated and feasible adjunct antiplatelet therapy in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

High-dose rFVIIa increases arterial thrombosis risk in ICH patients

Posted: 17 Dec 2009 04:00 PM PST

Treatment with recombinant activated factor VII in patients with intracerebral hemorrhage is associated with a small increased risk for arterial thromboembolism, an analysis of clinical trial data suggests.

Thiazolidinediones do not influence stroke risk

Posted: 17 Dec 2009 04:00 PM PST

Patients with Type 2 diabetes do not face an altered risk for stroke if they take thiazolidinediones, show the results of a population-based study.

Good test-retest reliability with patient-reported dyspnea questionnaires

Posted: 17 Dec 2009 04:00 PM PST

Patient-reported dyspnea ratings are related to the stage of disease severity according to three widely used dyspnea questionnaires, report US researchers.

VCD prevalent in mild-to-moderate asthma

Posted: 17 Dec 2009 04:00 PM PST

Vocal cord dysfunction occurs in all types of patients with asthma and is particularly prevalent in patients with mild-to-moderate asthma, US research shows.

C-ACT complements other markers of asthma control

Posted: 17 Dec 2009 04:00 PM PST

The assessment of asthma control by the Childhood Asthma Control Test is significantly related to the level of fractional exhaled nitric oxide in newly diagnosed patients, a study findings show.

Self-perception deficits underpin schizophrenia delusions of influence

Posted: 17 Dec 2009 04:00 PM PST

Delusions of influence in schizophrenia are based on imprecise internal predictions of the sensory consequences of patients' actions that cause them to rely on external agency cues, conclude German scientists.

No suicide attempt risk increase with anti-epileptics in bipolar patients

Posted: 17 Dec 2009 04:00 PM PST

Contrary to US Food and Drug Administration (FDA) reports, anti-epileptic drugs (AEDs) do not increase suicide risk among bipolar disorder patients and may even be protective against suicide, say US researchers.

Adalimumab reduces psoriatic arthritis as well as psoriasis symptoms

Posted: 17 Dec 2009 04:00 PM PST

Psoriasis patients taking adalimumab for the treatment of moderate-to-severe psoriasis may also experience a reduction in comorbid psoriatic arthritis symptoms, research suggests.

HDL and LDL cholesterol effects of statins unrelated

Posted: 17 Dec 2009 04:00 PM PST

The impact of statins on high-density lipoprotein levels is unrelated to their effect on low-density lipoprotein concentrations, a meta-analysis of over 30,000 patients suggests.

Protective effect of intensive statin dose endures beyond first CV event

Posted: 17 Dec 2009 04:00 PM PST

Vascular clinical trials should monitor total rather than just first cardiovascular events, as these are equally impacted by the intensity of statin treatment, say US researchers.

Elderly GI surgery improvement initiatives ‘need expanding’

Posted: 17 Dec 2009 04:00 PM PST

Quality improvement initiatives for elderly individuals undergoing gastrointestinal surgery need to be expanded, say researchers after finding markedly elevated morbidity and mortality in this group.

Gum disease strong predictor for Type 2 diabetes

Posted: 17 Dec 2009 04:00 PM PST

Almost all individuals with gum disease are significantly at risk for Type 2 diabetes, say researchers.

Thiazolidinediones do not influence stroke risk

Posted: 17 Dec 2009 04:00 PM PST

Patients with Type 2 diabetes do not face an altered risk for stroke if they take thiazolidinediones, show the results of a population-based study.

Elinogrel promising adjunct to PCI for STEMI

Posted: 17 Dec 2009 04:00 PM PST

Results of pilot study show that elinogrel, a novel P2Y12 ADP-receptor antagonist, is a well-tolerated and feasible adjunct antiplatelet therapy in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

Benefit of drug-eluting stents limited to stable CAD

Posted: 17 Dec 2009 04:00 PM PST

Drug-eluting stents reduce the need for repeat revascularization relative to bare metal stents in patients with stable coronary artery disease, but appear to have little such benefit for those with unstable angina or non–ST elevation acute coronary syndromes, study findings show.

Novel breast tissue feature linked to breast cancer risk

Posted: 17 Dec 2009 04:00 PM PST

Higher acinar counts within the lobules and larger lobule size are associated with an increased risk for breast cancer in women who have had benign breast biopsies, US researchers report.

Ninety-day stroke recurrence risk estimator published online

Posted: 16 Dec 2009 04:00 PM PST

Researchers at Harvard Medical School have developed a web-based tool to predict a patient's early risk for recurrence after ischemic stroke.

Healthy weight and exercise reduce urinary problems in prostate surgery patients

Posted: 16 Dec 2009 04:00 PM PST

Men who are physically active and maintain a healthy weight have a lower risk for developing urinary incontinence after surgery for prostate cancer than men who are obese and physically inactive, report researchers.

MRI-guided prostate biopsy finds clinically significant cancer

Posted: 16 Dec 2009 04:00 PM PST

Magnetic resonance imaging is highly effective at detecting localized clinically significant prostate cancer, study findings show.

Healthy weight and exercise reduce urinary problems in prostate surgery patients

Posted: 16 Dec 2009 04:00 PM PST

Men who are physically active and maintain a healthy weight have a lower risk for developing urinary incontinence after surgery for prostate cancer than men who are obese and physically inactive, report researchers.

MRI-guided prostate biopsy finds clinically significant cancer

Posted: 16 Dec 2009 04:00 PM PST

Magnetic resonance imaging is highly effective at detecting localized clinically significant prostate cancer, study findings show.

Psychological factors linked to the metabolic syndrome in CHD patients

Posted: 16 Dec 2009 04:00 PM PST

Depression, anger, hostility, and pessimism are all linked to an increased likelihood of having the metabolic syndrome in patients with stable coronary heart disease, a US study indicates.

IDEAL trial shows persistent protection with high-dose atorvastatin

Posted: 16 Dec 2009 04:00 PM PST

Patients receiving intensive statin therapy should continue to do so even if they experience a cardiovascular event, say researchers who found the additional protective effect of a high versus standard statin dose persists through multiple events.

High comorbidity impacts intensive glucose therapy for Type 2 diabetics

Posted: 16 Dec 2009 04:00 PM PST

Type 2 diabetes patients with high levels of comorbidity may not gain maximum cardiovascular benefit from intensive glucose therapy, report US researchers.

Coffee and tea drinking may reduce risk for Type 2 diabetes

Posted: 16 Dec 2009 04:00 PM PST

Results from a systematic review and meta-analysis suggest that high intake of normal and decaffeinated coffee and tea may lower the risk for Type 2 diabetes.

High comorbidity impacts intensive glucose therapy for Type 2 diabetics

Posted: 16 Dec 2009 04:00 PM PST

Type 2 diabetes patients with high levels of comorbidity may not gain maximum cardiovascular benefit from intensive glucose therapy, report US researchers.

Novel breast tissue feature linked to breast cancer risk

Posted: 16 Dec 2009 04:00 PM PST

Higher acinar counts within the lobules and larger lobule size are associated with an increased risk for breast cancer in women who have had benign breast biopsies, US researchers report.

DHA may improve breast cancer chemotherapy outcome

Posted: 16 Dec 2009 04:00 PM PST

Adding docosahexaenoic acid to chemotherapy can slow progression and improve survival among patients with metastatic breast cancer, without adverse side effects, French research shows.

Brachytherapy offers superior cancer control for prostate patients

Posted: 15 Dec 2009 04:00 PM PST

Brachytherapy (BT) achieves superior cancer control in prostate cancer patients with low- or intermediate-risk disease compared with external beam radiotherapy (EBRT), but at the cost of higher rates of urinary toxicity, report researchers.

DC-SCRIPT may have prognostic value in breast cancer

Posted: 15 Dec 2009 04:00 PM PST

Dendritic cell-specific transcript is a key regulator of nuclear receptor activity that may have prognostic value in breast cancer, according to researchers from The Netherlands.

Active surveillance candidates may harbor aggressive prostate cancer

Posted: 14 Dec 2009 04:00 PM PST

Some prostate cancer patients who are suitable for active surveillance protocols may in fact harbor aggressive disease, research findings show.

Prostate cancer diagnosis raises suicide and cardiovascular risks

Posted: 14 Dec 2009 04:00 PM PST

Newly diagnosed prostate cancer patients have a higher risk for cardiovascular events and are more likely to commit suicide than men in the general population, study results show.

Breast cancer clinical work-up takes longer in African–American women

Posted: 14 Dec 2009 04:00 PM PST

Researchers investigating the time it takes to complete diagnostic testing for breast cancer have found a significant racial disparity among low-income women from South Carolina, USA.

Sexual function stops declining after 2 years in prostate EBRT patients

Posted: 13 Dec 2009 04:00 PM PST

Contrary to conventional wisdom, men treated with external beam radiotherapy for prostate cancer experience a decline in sexual function for 2 years after treatment at which point it stabilizes, report researchers.

Katz nomogram superior to Louisville scores models

Posted: 13 Dec 2009 04:00 PM PST

The Katz nomogram outperforms the two Louisville scores models when predicting axillary lymph node involvement in patients with breast cancer, French researchers report.

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