Medical News

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• Nasal symptoms common in patients with work-exacerbated asthma
• Reduced IL-10 and IFN-γ levels linked to polysensitization in children
• Study reveals high productivity losses due to rhinitis
• Jaw problems and tooth wear risk raised in schizophrenia
• Dopamine plays ‘important’ role in bipolar disorder
• Celiac disease precedes Type 1 diabetes in pediatric patients
• Paracetamol enhances lidocaine’s intravenous regional anesthesia effect
• FIC block effective analgesic before spinal anesthesia for femoral neck fracture
• peri-operative fluid therapy may be suboptimal
• GM-CSF therapy restores monocytic immunocompetence in sepsis patients
• Phenylephrine outweighs ephedrine during spinal anesthesia for cesarean
• DES thrombosis risk high after clopidogrel withdrawal within 6 months
• Childhood cancer survivors ‘face increased stroke risk’
• Two years after treatment, PSA level predicts long-term prostate cancer survival
• WPRT for prostate cancer helps reduce disease recurrence
• Two years after treatment, PSA level predicts long-term prostate cancer survival
• Breast cancer chemotherapy harms bone health
• WPRT for prostate cancer helps reduce disease recurrence
• Continued rise in obesity may outweigh health gains from smoking decline
• Diet of trans fat plus MSG could affect spatial memory
• Longstanding diabetes ‘impairs cardiac structure and function’
• Sitagliptin non-inferior to metformin as monotherapy in Type 2 diabetes
• Focused update of US guidelines on STEMI and PCI management published
• Field triage of PCI patients ‘independently improves outcome’
• Breast cancer chemotherapy harms bone health
• Moderate exercise can reduce side effects of hormone therapy for prostate cancer
• Chemotherapy-induced leucopenia linked to amenorrhea in young women
• PSA velocity able to identify clinically significant disease
• Researchers call for standardized reporting of prostate surgery complications
• Anti-HER2 therapy ‘should be considered’ for HER2-positive, node negative breast cancer
• Vitamin D is not associated with prostate cancer risk
• CYP2C8 polymorphism may predict tamoxifen response

Nasal symptoms common in patients with work-exacerbated asthma Posted: 03 Dec 2009 04:00 PM PST Nasal symptoms are very common in people with work-exacerbated asthma, although they are less severe than nasal symptoms in people with occupational asthma, researchers have found.

Reduced IL-10 and IFN-γ levels linked to polysensitization in children Posted: 03 Dec 2009 04:00 PM PST Children who are sensitized to multiple allergens have lower levels of interleukin-10 and interferon-gamma than those who are monosensitized, results from a preliminary study suggest.

Study reveals high productivity losses due to rhinitis Posted: 03 Dec 2009 04:00 PM PST Study results show that rhinitis costs Sweden €2.7 billion per year in terms of lost productivity.

Jaw problems and tooth wear risk raised in schizophrenia Posted: 03 Dec 2009 04:00 PM PST Chronically hospitalized schizophrenia patients are significantly more likely to develop temporomandibular disorder and severe tooth wear than healthy individuals, conclude Turkish researchers.

Dopamine plays ‘important’ role in bipolar disorder Posted: 03 Dec 2009 04:00 PM PST The dopaminergic system appears to play a central role in the pathophysiology of bipolar disorder and may point the way to novel treatments, the results of a review indicate.

Celiac disease precedes Type 1 diabetes in pediatric patients Posted: 03 Dec 2009 04:00 PM PST Celiac disease can develop before Type 1 diabetes in children with the two conditions, suggests research presented this week at Gastro 2009 in London, UK.

Paracetamol enhances lidocaine’s intravenous regional anesthesia effect Posted: 03 Dec 2009 04:00 PM PST Paracetamol appears to enhance the analgesic effects of lidocaine when used during intravenous regional anesthesia, study findings show.

FIC block effective analgesic before spinal anesthesia for femoral neck fracture Posted: 03 Dec 2009 04:00 PM PST A fascia iliaca compartment block may be more effective than intravenous alfentanil for facilitating the lateral position of spinal anesthesia in elderly patients undergoing surgery for femoral neck fractures, say researchers.

peri-operative fluid therapy may be suboptimal Posted: 03 Dec 2009 04:00 PM PST Researchers suggest that to optimize peri-operative fluid management, fixed crystalloid administration may need to be combined with individualized goal-directed colloid administration.

GM-CSF therapy restores monocytic immunocompetence in sepsis patients Posted: 03 Dec 2009 04:00 PM PST Biomarker-guided granulocyte–macrophage colony-stimulating factor therapy restores monocytic immunocompetence in patients in the later stages of sepsis, study findings show.

Phenylephrine outweighs ephedrine during spinal anesthesia for cesarean Posted: 03 Dec 2009 04:00 PM PST Phenylephrine may be a more favorable option for the treatment of hypotension during spinal anesthesia for cesarean delivery than ephedrine, say researchers after finding ephedrine crosses the placenta to a greater extent and undergoes less metabolism and redistribution in the fetus.

DES thrombosis risk high after clopidogrel withdrawal within 6 months Posted: 02 Dec 2009 04:00 PM PST Patients may be at particularly high risk for stent thrombosis if clopidogrel is withdrawn in the first 6 months after receiving a drug-eluting stent, study findings suggest.

Childhood cancer survivors ‘face increased stroke risk’ Posted: 02 Dec 2009 04:00 PM PST Adult survivors of certain childhood cancers face an increased risk for stroke and cerebrovascular disease, US researchers warn in the journal Neurology.

Two years after treatment, PSA level predicts long-term prostate cancer survival Posted: 02 Dec 2009 04:00 PM PST The 2-year post-treatment prostate-specific antigen levels of men treated with radiotherapy for prostate cancer indicates whether their cancer is likely to metastasize or they are likely to die from the disease, researchers say.

WPRT for prostate cancer helps reduce disease recurrence Posted: 02 Dec 2009 04:00 PM PST Study results show that men with advanced or aggressive prostate cancer may have better biochemical disease-free survival rates if they are treated with whole pelvic radiotherapy rather than prostate-only radiotherapy.

Two years after treatment, PSA level predicts long-term prostate cancer survival Posted: 02 Dec 2009 04:00 PM PST The 2-year post-treatment prostate-specific antigen levels of men treated with radiotherapy for prostate cancer indicates whether their cancer is likely to metastasize or they are likely to die from the disease, researchers say.

Breast cancer chemotherapy harms bone health Posted: 02 Dec 2009 04:00 PM PST Researchers in Germany have confirmed the deleterious effect of doxorubicin and cyclophosphamide on bone health in premenopausal women with breast cancer, and show that quantitative ultrasonography can be used to monitor these patients.

WPRT for prostate cancer helps reduce disease recurrence Posted: 02 Dec 2009 04:00 PM PST Study results show that men with advanced or aggressive prostate cancer may have better biochemical disease-free survival rates if they are treated with whole pelvic radiotherapy rather than prostate-only radiotherapy.

Continued rise in obesity may outweigh health gains from smoking decline Posted: 02 Dec 2009 04:00 PM PST Recent increases in obesity could outweigh the positive health effects of declining rates of smoking in the US population if left unchecked until 2020, say researchers.

Diet of trans fat plus MSG could affect spatial memory Posted: 02 Dec 2009 04:00 PM PST A diet containing trans fat and the flavour enhancer monosodium glutamate not only induces dyslipidemia but could also affect cognitive spatial memory, a study in mice suggests.

Longstanding diabetes ‘impairs cardiac structure and function’ Posted: 02 Dec 2009 04:00 PM PST Chronic diabetes is associated with an accelerated aging of the heart and a decline in left ventricular structure and function, a German population study suggests.

Sitagliptin non-inferior to metformin as monotherapy in Type 2 diabetes Posted: 02 Dec 2009 04:00 PM PST Sitagliptin is non-inferior to metformin for improving glycemic control in treatment-naïve patients with Type 2 diabetes, results of a double-blind study suggest.

Focused update of US guidelines on STEMI and PCI management published Posted: 02 Dec 2009 04:00 PM PST The American Heart Association, American College of Cardiology, and Society for Cardiovascular Angiography Interventions have jointly issued a "focused update" of guidelines for the management of ST-segment elevation myocardial infarction patients and percutaneous coronary intervention.

Field triage of PCI patients ‘independently improves outcome’ Posted: 02 Dec 2009 04:00 PM PST Researchers in Denmark report that field triage significantly reduces treatment delay and improves the outcome of ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention, even after taking baseline variables into account.

Breast cancer chemotherapy harms bone health Posted: 02 Dec 2009 04:00 PM PST Researchers in Germany have confirmed the deleterious effect of doxorubicin and cyclophosphamide on bone health in premenopausal women with breast cancer, and show that quantitative ultrasonography can be used to monitor these patients.

Moderate exercise can reduce side effects of hormone therapy for prostate cancer Posted: 01 Dec 2009 04:00 PM PST A brief program of resistance and aerobic exercise significantly relieves the adverse effects of androgen suppression therapy in prostate cancer patients, researchers report.

Chemotherapy-induced leucopenia linked to amenorrhea in young women Posted: 01 Dec 2009 04:00 PM PST A lower leukocyte count after treatment with fluorouracil, epirubicin, and cyclophosphamide is associated with an increased risk for amenorrhea in young, premenopausal women with breast cancer, study findings indicate.

PSA velocity able to identify clinically significant disease Posted: 30 Nov 2009 04:00 PM PST Prostate-specific antigen velocity may be a useful addition to prostate cancer screening protocols in the accurate identification of patients with clinically significant disease, study findings show.

Researchers call for standardized reporting of prostate surgery complications Posted: 30 Nov 2009 04:00 PM PST Complications associated with prostate surgery should be reported in a standardized manner, state researchers.

Anti-HER2 therapy ‘should be considered’ for HER2-positive, node negative breast cancer Posted: 30 Nov 2009 04:00 PM PST Patients with small, node-negative, human epidermal growth factor receptor 2–positive breast cancer have a significant risk for relapse and should be considered for systemic, anti-HER2, adjuvant therapy, say researchers.

Vitamin D is not associated with prostate cancer risk Posted: 29 Nov 2009 04:00 PM PST Vitamin D is not associated with prostate cancer incidence, say researchers.

CYP2C8 polymorphism may predict tamoxifen response Posted: 29 Nov 2009 04:00 PM PST Polymorphisms in the cytochrome P450 2C8 and CYP2C9 genes may influence breast tumor characteristics and disease-free survival in tamoxifen-treated patients, Swedish researchers report.

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