Medical News

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• Off-licence recombinant activated factor VII guidelines often ignored
• Stent-assisted coiling of aneurysms lowers recurrence but at cost of more complications
• PSA density effectively predicts Gleason score upgrading after prostate surgery
• <i>BRIP1</i> mutations found in hereditary prostate cancer families
• Tamoxifen following chemotherapy improves breast cancer outcome
• PSA density effectively predicts Gleason score upgrading after prostate surgery
• <i>BRIP1</i> mutations found in hereditary prostate cancer families
• Adiponectin may be marker for metabolic syndrome in menopausal women
• <i>PTPN1</i> variants are associated with high total and LDL cholesterol
• Diabetes impacts myocardial postconditioning success
• Anemia linked to subclinical CVD markers in men with Type 2 diabetes
• Cardiotoxicity of cancer therapies raised again; co-operation of cardiologists and oncologists urged
• Additional antithrombotics increase bleeding risk in MI patients
• Tamoxifen following chemotherapy improves breast cancer outcome

Off-licence recombinant activated factor VII guidelines often ignored Posted: 10 Dec 2009 04:00 PM PST A study of hospitals in Australia and New Zealand has revealed that although most have guidelines for off-license recombinant activated factor VII use, the majority of patients are not treated in accordance with all elements of the guideline.

Stent-assisted coiling of aneurysms lowers recurrence but at cost of more complications Posted: 10 Dec 2009 04:00 PM PST Stent-assisted coiling of intracranial aneurysms is associated with improved angiographic outcomes but also more procedure-related complications compared with stent-free coiling, researchers report.

PSA density effectively predicts Gleason score upgrading after prostate surgery Posted: 10 Dec 2009 04:00 PM PST Prostate-specific antigen density significantly predicts Gleason score upgrading in men who are treated with radical prostatectomy for prostate cancer, report researchers.

<i>BRIP1</i> mutations found in hereditary prostate cancer families Posted: 10 Dec 2009 04:00 PM PST Researchers have found that men with hereditary prostate cancer have missense, but not protein truncating, variants in the BRIP1 gene.

Tamoxifen following chemotherapy improves breast cancer outcome Posted: 10 Dec 2009 04:00 PM PST Addition of chemotherapy to standard tamoxifen treatment for postmenopausal women with node-positive breast cancer significantly improves disease-free survival, and this benefit is maximized when the tamoxifen follows chemotherapy, US researchers report in The Lancet.

PSA density effectively predicts Gleason score upgrading after prostate surgery Posted: 10 Dec 2009 04:00 PM PST Prostate-specific antigen density significantly predicts Gleason score upgrading in men who are treated with radical prostatectomy for prostate cancer, report researchers.

<i>BRIP1</i> mutations found in hereditary prostate cancer families Posted: 10 Dec 2009 04:00 PM PST Researchers have found that men with hereditary prostate cancer have missense, but not protein truncating, variants in the BRIP1 gene.

Adiponectin may be marker for metabolic syndrome in menopausal women Posted: 10 Dec 2009 04:00 PM PST Adiponectin may be a marker for the metabolic syndrome in overweight and obese postmenopausal women with abnormal waist circumferences, say researchers who found low adiponectin levels in this group.

<i>PTPN1</i> variants are associated with high total and LDL cholesterol Posted: 10 Dec 2009 04:00 PM PST Three variants in the protein tyrosine phosphatase non-receptor type 1 gene are associated with elevated total and low-density lipoprotein cholesterol in men of normal weight, show study results.

Diabetes impacts myocardial postconditioning success Posted: 10 Dec 2009 04:00 PM PST Administration of the volatile anesthetic desflurane on reoxygenation of hypoxic myocardium can provoke a protective postconditioning response even in diabetic patients, a laboratory study indicates.

Anemia linked to subclinical CVD markers in men with Type 2 diabetes Posted: 10 Dec 2009 04:00 PM PST Study findings suggest that anemia is associated with an increased cardiovascular risk profile in men with Type 2 diabetes.

Cardiotoxicity of cancer therapies raised again; co-operation of cardiologists and oncologists urged Posted: 10 Dec 2009 04:00 PM PST Cardiologists and oncologists should work together to avoid the adverse cardiovascular effects of certain chemotherapies, recommend authors of a review published in the Journal of the National Cancer Institute.

Additional antithrombotics increase bleeding risk in MI patients Posted: 10 Dec 2009 04:00 PM PST The risk for bleeding associated with antithrombotic treatment among myocardial infarction patients increases in proportion to the number of antithrombotic drugs used, report researchers in The Lancet.

Tamoxifen following chemotherapy improves breast cancer outcome Posted: 10 Dec 2009 04:00 PM PST Addition of chemotherapy to standard tamoxifen treatment for postmenopausal women with node-positive breast cancer significantly improves disease-free survival, and this benefit is maximized when the tamoxifen follows chemotherapy, US researchers report in The Lancet.

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