Medical News

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• Pediatric psoriasis increases with increasing age
• High-dose 3DCRT well tolerated by prostate cancer patients
• Claustrophobia hinders uptake of MR breast cancer screening by high risk women
• Radiation and surgery for prostate cancer result in similar QoL ‘utility’ scores
• Novel risk stratification tool effective at selecting prostate cancer patients at risk for BM
• CY and DOX enhance bioactivity of GM-CSF–secreting breast tumor vaccine
• Biochemical response key to determining benefit of neoadjuvant ADT
• Being underweight increases breast cancer recurrence and death
• Hypofractionated RT and adjuvant AST is well tolerated in prostate cancer patients
• CAPRA score and Stephenson nomogram superior for predicting biochemical recurrence
• <i>ERCC4</i> SNP does not modify breast cancer risk in <i>BRCA1/2</i> mutation carriers

Pediatric psoriasis increases with increasing age Posted: 24 Dec 2009 04:00 PM PST The incidence of pediatric psoriasis has increased over recent years, say researchers whose study also refutes the hypothesis that there is a dual peak in psoriasis incidence.

High-dose 3DCRT well tolerated by prostate cancer patients Posted: 23 Dec 2009 04:00 PM PST A long-term follow-up study of prostate cancer patients in the Radiation Therapy Oncology Group 9406 study found that tolerance to high-dose 3DCRT remained excellent for up to 12 years.

Claustrophobia hinders uptake of MR breast cancer screening by high risk women Posted: 23 Dec 2009 04:00 PM PST Claustrophobia is preventing a lot of women at high risk for breast cancer from undergoing supplemental magnetic resonance imaging, researchers report.

Radiation and surgery for prostate cancer result in similar QoL ‘utility’ scores Posted: 22 Dec 2009 04:00 PM PST Prostate cancer patients treated with radical prostatectomy have similar quality of life utility scores 1 year after treatment as their peers receiving radiation therapy, despite having different symptom profiles, study findings show.

Novel risk stratification tool effective at selecting prostate cancer patients at risk for BM Posted: 22 Dec 2009 04:00 PM PST Italian researchers have used a novel risk stratification tool to successfully evaluate which newly diagnosed prostate cancer patients require bone scans to detect potential bone metastasis.

CY and DOX enhance bioactivity of GM-CSF–secreting breast tumor vaccine Posted: 22 Dec 2009 04:00 PM PST Low-dose cyclophosphamide and doxorubicin may augment vaccine-induced HER2-specific immunity in breast cancer patients, say researchers.

Biochemical response key to determining benefit of neoadjuvant ADT Posted: 21 Dec 2009 04:00 PM PST Biochemical response to neoadjuvant androgen deprivation therapy before radiotherapy is a more critical determinant of prostate cancer patient outcome than total duration of therapy, report researchers.

Being underweight increases breast cancer recurrence and death Posted: 21 Dec 2009 04:00 PM PST Underweight breast cancer patients are at increased risk for poor overall survival and shorter time to recurrence, report researchers.

Hypofractionated RT and adjuvant AST is well tolerated in prostate cancer patients Posted: 20 Dec 2009 04:00 PM PST High-risk prostate cancer patients treated with large doses of intensity-modulated radiotherapy and androgen suppression therapy show no signs of long-term acute toxicity, researchers report.

CAPRA score and Stephenson nomogram superior for predicting biochemical recurrence Posted: 20 Dec 2009 04:00 PM PST Both the Cancer of the Prostate Risk Assessment score and Stephenson nomogram outperform the D'Amico risk stratification for predicting biochemical recurrence after radical prostatectomy, say researchers.

<i>ERCC4</i> SNP does not modify breast cancer risk in <i>BRCA1/2</i> mutation carriers Posted: 20 Dec 2009 04:00 PM PST Contrary to previous general population studies, a single nucleotide polymorphism in intron 1 of the ERCC4 gene does not reduce breast cancer risk in women carrying the BRCA1 and BRCA2 mutations, report researchers.

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