Medical News

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• Children with asthma may have dysregulated stress response
• Swimming pool use in early life may reduce asthma risk
• Early EBV infection may protect against persistent IgE sensitization
• Frequent high-potency cannabis use common in first-episode psychosis patients
• One-quarter of bipolar I disorder patients experience cycling episodes
• High BMI predicts failed dose adjustment in patients with HTPR
• Osteoporosis and low BMD are risk factors for stroke, death
• Prostate cancer invasion into bladder neck does not guarantee stage T4 cancer
• Algorithm improves patient selection for nerve-sparing prostate cancer surgery
• HER2 overexpression worsens outcome in women with small breast tumors
• SSRI treatment increases BDNF levels in postmenopausal women
• Biomarker panel shows promise in detecting epithelial ovarian cancer
• Annual ovarian cancer screening inadequate for high-risk population
• Leukocyte count predicts amenorrhea in breast cancer patients
• Clinical tool developed for predicting pregnancy rates in endometriosis patients
• Comparable IVF success in men with obstructive, non-obstructive azoospermia
• Low referral rates to reproductive specialists for women with cancer
• DMPA not linked to weight gain in obese women
• Experts support DMPA administration by trained community health workers
• Semen cryopreservation for oncology patients not widely used
• ITX5061 shows preliminary anti-atherosclerotic promise
• Metabolic syndrome linked to accelerated vascular aging
• Prolonged QRS marks out hypertensive patients at increased risk for SCD
• Prolonged QRS marks out hypertensive patients at increased risk for SCD
• Patient self-assessment score effective for diabetes prediction
• Psychosocial work stress increases Type 2 diabetes risk for middle-aged women
• Prolonged QRS marks out hypertensive patients at increased risk for SCD
• Arrhythmia linked to delayed reperfusion, myocardial damage in primary PCI

Children with asthma may have dysregulated stress response Posted: 07 Dec 2009 04:00 PM PST Children with asthma have lower cortisol levels in response to recurrent maternal distress than those without the respiratory condition, researchers have found.

Swimming pool use in early life may reduce asthma risk Posted: 07 Dec 2009 04:00 PM PST The use of swimming pools before the age of 2 years is associated with a slightly reduced risk for asthma and rhinitis symptoms, but an increased risk for eczema, in later childhood, research suggests.

Early EBV infection may protect against persistent IgE sensitization Posted: 07 Dec 2009 04:00 PM PST Infection with the Epstein-Barr virus in early life may protect against persistent immunoglobulin E sensitization, results from a Swedish study suggest.

Frequent high-potency cannabis use common in first-episode psychosis patients Posted: 07 Dec 2009 04:00 PM PST Individuals with a first episode of psychosis smoke high-potency cannabis for longer durations and with a greater frequency than healthy individuals without psychosis, show UK researchers.

One-quarter of bipolar I disorder patients experience cycling episodes Posted: 07 Dec 2009 04:00 PM PST Researchers have found that cycling episodes constitute a quarter of all episodes in bipolar I disorder, suggesting that such a classification should be added to current diagnostic criteria.

High BMI predicts failed dose adjustment in patients with HTPR Posted: 06 Dec 2009 04:00 PM PST High body mass index, acute coronary syndrome, diabetes mellitus, and the cytochrome P450 2C19*2 polymorphism predict high on-treatment platelet reactivity after treatment with the antiplatelet agent clopidogrel, research shows.

Osteoporosis and low BMD are risk factors for stroke, death Posted: 06 Dec 2009 04:00 PM PST Low bone mineral density and osteoporosis are independent risk factors for stroke and death, a large cohort study has found.

Prostate cancer invasion into bladder neck does not guarantee stage T4 cancer Posted: 06 Dec 2009 04:00 PM PST Prostate cancer that invades the bladder neck should not automatically be designated a stage T4 cancer, as it currently is under the American Joint Committee on Cancer's classification, say researchers.

Algorithm improves patient selection for nerve-sparing prostate cancer surgery Posted: 06 Dec 2009 04:00 PM PST Japanese researchers have developed an algorithm that helps clinicians select prostate cancer patients who can undergo nerve-sparing prostate surgery without comprising surgical margin status.

HER2 overexpression worsens outcome in women with small breast tumors Posted: 06 Dec 2009 04:00 PM PST Human epidermal growth factor receptor 2 status has clinical relevance in patients with small, node-negative breast cancer, Italian researchers report.

SSRI treatment increases BDNF levels in postmenopausal women Posted: 06 Dec 2009 04:00 PM PST Symptomatic postmenopausal women who take a low dose of paroxetine, a selective serotonin reuptake inhibitor, show an improvement in menopausal symptoms that may be a result of increased plasma brain-derived neurotrophic factor levels, according to Italian researchers.

Biomarker panel shows promise in detecting epithelial ovarian cancer Posted: 06 Dec 2009 04:00 PM PST Patients with suspected epithelial ovarian cancer within a pelvic mass can be differentially diagnosed using a combination of three serum biomarkers, suggest US study findings.

Annual ovarian cancer screening inadequate for high-risk population Posted: 06 Dec 2009 04:00 PM PST Final Phase I results from the UK Familial Ovarian Cancer Screening Study indicate that annual screening for familial ovarian cancer is not adequate for high-risk populations.

Leukocyte count predicts amenorrhea in breast cancer patients Posted: 06 Dec 2009 04:00 PM PST Young, premenopausal women with breast cancer who have low leukocyte counts after treatment with fluorouracil, epirubicin, and cyclophosphamide have a higher risk for amenorrhea than those with normal counts, study findings indicate.

Clinical tool developed for predicting pregnancy rates in endometriosis patients Posted: 06 Dec 2009 04:00 PM PST Two US researchers have developed a validated clinical tool that predicts pregnancy rates after endometriosis surgical staging, and enables clinicians to identify patients with good or poor prognoses and potentially save unnecessary treatment costs.

Comparable IVF success in men with obstructive, non-obstructive azoospermia Posted: 06 Dec 2009 04:00 PM PST Men with non-obstructive azoospermia and obstructive azoopsermia are equally capable of fathering a child through IVF, suggest study results.

Low referral rates to reproductive specialists for women with cancer Posted: 06 Dec 2009 04:00 PM PST Results of a US survey show that although most oncologists at academic medical centers discuss the risk for infertility with female cancer patients, referrals to reproductive endocrinologists are not routinely made.

DMPA not linked to weight gain in obese women Posted: 06 Dec 2009 04:00 PM PST Normal and overweight, but not obese, women show an increase in body mass index associated with depot-medroxyprogesterone acetate duration of use, show Brazilian researchers.

Experts support DMPA administration by trained community health workers Posted: 06 Dec 2009 04:00 PM PST Following a meeting held at the World Health Organization in Geneva, experts support the community-based provision of progestin-only injectable contraceptives by appropriately trained community health workers.

Semen cryopreservation for oncology patients not widely used Posted: 06 Dec 2009 04:00 PM PST Doctors should routinely offer sperm cryopreservation to cancer patients, suggest researchers who found that success rates after assisted reproductive technology are good, yet uptake appears modest.

ITX5061 shows preliminary anti-atherosclerotic promise Posted: 06 Dec 2009 04:00 PM PST An investigational drug known as ITX5061 increases levels of high-density lipoprotein cholesterol and apolipoprotein A-I in humans and mice, US investigators report.

Metabolic syndrome linked to accelerated vascular aging Posted: 06 Dec 2009 04:00 PM PST The metabolic syndrome "dramatically" accelerates age-associated abnormalities in arterial structure and function, an Italian population study has shown.

Prolonged QRS marks out hypertensive patients at increased risk for SCD Posted: 06 Dec 2009 04:00 PM PST Prolonged QRS duration was independently associated with an increased risk for sudden cardiac death in hypertensive patients undergoing intensive blood-pressure lowering therapy in the LIFE study, a US team reports.

Prolonged QRS marks out hypertensive patients at increased risk for SCD Posted: 06 Dec 2009 04:00 PM PST Prolonged QRS duration was independently associated with an increased risk for sudden cardiac death in hypertensive patients undergoing intensive blood-pressure lowering therapy in the LIFE study, a US team reports.

Patient self-assessment score effective for diabetes prediction Posted: 06 Dec 2009 04:00 PM PST Study results show that a new patient self-assessment score for evaluating diabetes risk, developed using data from NHANES 1999 to 2004, offers advantages over other methods.

Psychosocial work stress increases Type 2 diabetes risk for middle-aged women Posted: 06 Dec 2009 04:00 PM PST Results from the Whitehall II study show that psychosocial work stress doubles the risk for Type 2 diabetes in middle-aged women, but not men.

Prolonged QRS marks out hypertensive patients at increased risk for SCD Posted: 06 Dec 2009 04:00 PM PST Prolonged QRS duration was independently associated with an increased risk for sudden cardiac death in hypertensive patients undergoing intensive blood-pressure lowering therapy in the LIFE study, a US team reports.

Arrhythmia linked to delayed reperfusion, myocardial damage in primary PCI Posted: 06 Dec 2009 04:00 PM PST Accelerated idioventricular rhythm is associated with increased myocardial damage and delayed microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention, research reveals.

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