Medical News

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• Coagulation factors involved in moderate and severe asthma
• PTEN implicated in COPD
• Serial PEF measurements sensitive, specific for diagnosing occupational asthma
• H. pylori has no impact on postmenopausal bone density
• Jaw problems and tooth wear risk raised in schizophrenia
• Prepregnancy overweight increases risk for diabetes and hypertension
• Sulphonylureas associated with higher risk for HF, death than metformin
• Dopamine plays ‘important’ role in bipolar disorder
• Psychosis outcomes and symptoms linked to temperament
• Bipolar concentration problems predict employment status
• Depression during psychosis prodrome predicts depression, self-harm
• Enzyme replacement improves cardiac endpoints in Fabry’s disease patients
• Auditory attention independent of mood, medication, psychosis in BD
• Facial processing deficits in schizophrenia linked to worse symptoms
• ICD benefit in SCD-HeFT driven by ventricular tachyarrhythmia mortality reduction
• Multiparametric echo strategy may improve ability to predict CRT response
• Initial prodrome of bipolar disorder not specific for later illness

Coagulation factors involved in moderate and severe asthma Posted: 06 Dec 2009 04:00 PM PST New research provides evidence of activation of the extrinsic coagulation cascade in the asthmatic airway.

PTEN implicated in COPD Posted: 06 Dec 2009 04:00 PM PST An exploratory gene-based analysis has identified a number of genes significantly associated with chronic obstructive pulmonary disease susceptibility, of which PTEN remained significant after multiple adjustments.

Serial PEF measurements sensitive, specific for diagnosing occupational asthma Posted: 06 Dec 2009 04:00 PM PST A new method of analysis developed to detect late asthmatic reactions following specific inhalation testing complements other validated methods of peak expiratory flow measurements for the diagnosis of occupational asthma, research shows.

H. pylori has no impact on postmenopausal bone density Posted: 06 Dec 2009 04:00 PM PST Helicobacter pylori infection does not have a negative effect on bone mineral density in postmenopausal women, indicate study findings presented at the Gastro 2009 meeting, held in London, UK.

Jaw problems and tooth wear risk raised in schizophrenia Posted: 03 Dec 2009 04:00 PM PST Chronically hospitalized schizophrenia patients are significantly more likely to develop temporomandibular disorder and severe tooth wear than healthy individuals, conclude Turkish researchers.

Prepregnancy overweight increases risk for diabetes and hypertension Posted: 03 Dec 2009 04:00 PM PST Researchers report that prepregnancy overweight is associated with significantly increased risks for subsequent diabetes and hypertension.

Sulphonylureas associated with higher risk for HF, death than metformin Posted: 03 Dec 2009 04:00 PM PST Treatment of patients with Type 2 diabetes with second-generation sulphonylureas significantly increases their risk for congestive heart failure compared with metformin therapy, show study results.

Dopamine plays ‘important’ role in bipolar disorder Posted: 03 Dec 2009 04:00 PM PST The dopaminergic system appears to play a central role in the pathophysiology of bipolar disorder and may point the way to novel treatments, the results of a review indicate.

Psychosis outcomes and symptoms linked to temperament Posted: 02 Dec 2009 04:00 PM PST Both symptoms and functional outcomes among psychosis patients are associated with temperament traits, conclude European investigators.

Bipolar concentration problems predict employment status Posted: 02 Dec 2009 04:00 PM PST Self-reported concentration problems predict whether or not bipolar I disorder patients achieve stable employment, the results of a study indicate.

Depression during psychosis prodrome predicts depression, self-harm Posted: 01 Dec 2009 04:00 PM PST Study findings suggest that comorbid depression during the prodromal phase of psychosis is a key contributor to the development of future depression and suicidal thinking.

Enzyme replacement improves cardiac endpoints in Fabry’s disease patients Posted: 01 Dec 2009 04:00 PM PST Enzyme replacement therapy over a 5-year period reduced cardiac mass and dysfunction as well as decreasing pain and improving quality-of-life measures in patients with Fabry's disease, according to an observational study of registry data.

Auditory attention independent of mood, medication, psychosis in BD Posted: 01 Dec 2009 04:00 PM PST Study findings suggest that disrupted auditory attention is observed in bipolar disorder patients independent of their mood state, medication status, or history of psychotic features, but may be influenced by the presence of a comorbid anxiety disorder.

Facial processing deficits in schizophrenia linked to worse symptoms Posted: 30 Nov 2009 04:00 PM PST Schizophrenia patients have deficits in facial expression and orientation processing, which are linked to worse symptoms and reduced social functioning, the results of a US study reveal.

ICD benefit in SCD-HeFT driven by ventricular tachyarrhythmia mortality reduction Posted: 30 Nov 2009 04:00 PM PST A substudy of SCD-HeFT demonstrates that implantable cardioverter defibrillator therapy reduced cardiac mortality through a reduction in presumed ventricular tachyarrhythmias, having no impact on heart failure mortality.

Multiparametric echo strategy may improve ability to predict CRT response Posted: 30 Nov 2009 04:00 PM PST A multiparametric echocardiographic strategy is better at identifying heart failure patients likely to respond to cardiac resynchronization therapy than existing single parametric approaches, a study indicates.

Initial prodrome of bipolar disorder not specific for later illness Posted: 30 Nov 2009 04:00 PM PST Although mood and energy dysregulation are characteristic of the initial prodrome of bipolar disorder, their low specificity does not allow the prediction of bipolar disorder development, conclude Norwegian researchers.

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