Medical News

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• Black people have elevated risk for stent thrombosis
• Cognitive effects of cannabis use ‘minimal’ in schizophrenia patients
• Substance abuse raises violent crime risk in BD patients
• Serious mental illnesses increased in psoriasis patients
• Lung transplant patients have high GERD prevalence
• Restrictive lung function linked to Type 2 diabetes and fatal CHD
• High Gleason score best predicts disease spread in prostate surgery patients
• High Gleason score best predicts disease spread in prostate surgery patients
• Microalbuminuria may identify high-risk metabolic syndrome patients
• Fatty-acid consumption linked with hypertension in older women
• Saxagliptin noninferior to sitagliptin for treating Type 2 diabetes
• Moderate coffee and alcohol intake may reduce risk for Type 2 diabetes
• Patients often overestimate PCI benefits
• Somatic symptoms more predictive of CV risk than cognitive depressive symptoms
• Patient selection is biggest challenge for phase I breast cancer trials
• Cell adhesion and migration molecules implicated in prostate cancer progression
• 12-core biopsy no more effective at detecting prostate cancer than 8-core
• Model estimates recurrence risk following ductal carcinoma in situ
• Abdominal fat predicts adverse prostate cancer outcomes better than BMI
• Smoking not linked to ductal carcinoma in situ
• Low socioeconomic status linked to mental health in prostate cancer survivors
• <i>BRCA2</i> mutation indicates shorter survival in men with prostate cancer
• Targeted breast cancer strategies needed for Mexican-American women

Black people have elevated risk for stent thrombosis Posted: 09 Sep 2010 05:00 PM PDT Black ethnicity is an independent risk factor for developing stent thrombosis after implantation of a drug-eluting stent, US researchers report.

Cognitive effects of cannabis use ‘minimal’ in schizophrenia patients Posted: 09 Sep 2010 05:00 PM PDT Cannabis use has little effect on cognitive performance in schizophrenia patients or healthy individuals, Australian research suggests.

Substance abuse raises violent crime risk in BD patients Posted: 09 Sep 2010 05:00 PM PDT Patients with bipolar disorder (BD) who abuse drugs are significantly more likely to commit violent crime than is the general population, study results suggest.

Serious mental illnesses increased in psoriasis patients Posted: 09 Sep 2010 05:00 PM PDT Patients with psoriasis have an increased risk for clinical depression, anxiety, and suicidal behavior, including ideation and attempt, compared with the general population, study findings indicate.

Lung transplant patients have high GERD prevalence Posted: 09 Sep 2010 05:00 PM PDT Patients who have undergone lung transplantation have a high prevalence of gastroesophageal reflux disease, particularly those who have been retransplanted, report US researchers.

Restrictive lung function linked to Type 2 diabetes and fatal CHD Posted: 09 Sep 2010 05:00 PM PDT Researchers report that restrictive impairment of lung function, as indicated by low forced vital capacity and forced expiratory volume in 1 second, is associated with increased risk for incident Type 2 diabetes and fatal coronary heart disease in middle-aged men.

High Gleason score best predicts disease spread in prostate surgery patients Posted: 08 Sep 2010 05:00 PM PDT Patients with a Gleason score of 6 or less after radical prostatectomy have at least an 80% chance of organ-confined prostate cancer and negative surgical margins, translating to a "very high rate of cure," say US researchers.

High Gleason score best predicts disease spread in prostate surgery patients Posted: 08 Sep 2010 05:00 PM PDT Patients with a Gleason score of 6 or less after radical prostatectomy have at least an 80% chance of organ-confined prostate cancer and negative surgical margins, translating to a "very high rate of cure," say US researchers.

Microalbuminuria may identify high-risk metabolic syndrome patients Posted: 08 Sep 2010 05:00 PM PDT Microalbuminuria can help identify high-risk nondiabetic patients with the metabolic syndrome who could benefit from intensive medical therapy and lifestyle changes, US researchers claim.

Fatty-acid consumption linked with hypertension in older women Posted: 08 Sep 2010 05:00 PM PDT Eating large quantities of saturated, monounsaturated, or trans-unsaturated fatty acids is associated with hypertension in middle-aged and older women, study findings indicate.

Saxagliptin noninferior to sitagliptin for treating Type 2 diabetes Posted: 08 Sep 2010 05:00 PM PDT Saxagliptin is noninferior to sitagliptin for the treatment of Type 2 diabetes when added to metformin therapy, show study results.

Moderate coffee and alcohol intake may reduce risk for Type 2 diabetes Posted: 08 Sep 2010 05:00 PM PDT Results from the Black Women's Health Study suggest that consumption of moderate amounts of caffeinated coffee and alcohol may reduce the risk for developing Type 2 diabetes.

Patients often overestimate PCI benefits Posted: 08 Sep 2010 05:00 PM PDT US researchers report that patients with angina often overestimate the benefits of percutaneous coronary intervention.

Somatic symptoms more predictive of CV risk than cognitive depressive symptoms Posted: 08 Sep 2010 05:00 PM PDT Somatic symptoms of depression are more strongly associated with cardiovascular events than are cognitive symptoms of depression in stable coronary heart disease patients, a US study suggests.

Patient selection is biggest challenge for phase I breast cancer trials Posted: 08 Sep 2010 05:00 PM PDT Around 20% of metastatic breast cancer patients who enter phase I clinical trials show a measurable benefit after 4 months, depending on their tumor characteristics and the biological activity of the novel agents, study results show.

Cell adhesion and migration molecules implicated in prostate cancer progression Posted: 07 Sep 2010 05:00 PM PDT Molecules that control cell migration and adhesion are under-expressed and differently distributed in prostate cancer compared with healthy tissue, show the results of an immunohistochemical study of prostate biopsy specimens.

12-core biopsy no more effective at detecting prostate cancer than 8-core Posted: 07 Sep 2010 05:00 PM PDT US study results indicate that prostate cancer detection is not improved by using a 12-core biopsy compared with an 8-core biopsy, flouting the assumption that more is better in prostate biopsy protocols.

Model estimates recurrence risk following ductal carcinoma in situ Posted: 07 Sep 2010 05:00 PM PDT US researchers have developed a nomogram that provides an individualized risk estimate for ipsilateral breast tumor recurrence in women with ductal carcinoma in situ treated with breast-conserving surgery.

Abdominal fat predicts adverse prostate cancer outcomes better than BMI Posted: 06 Sep 2010 05:00 PM PDT Abdominal fat is a better indicator of aggressive disease biology than overall body mass index in radiotherapy-treated prostate cancer patients, say Canadian researchers.

Smoking not linked to ductal carcinoma in situ Posted: 06 Sep 2010 05:00 PM PDT There is little evidence to suggest that cigarette smoking is associated with the risk for ductal carcinoma in situ of the breast among postmenopausal women, US researchers report.

Low socioeconomic status linked to mental health in prostate cancer survivors Posted: 05 Sep 2010 05:00 PM PDT Long-term prostate cancer survivors have worse mental health if they have a low rather than high socioeconomic status, show Dutch study results.

<i>BRCA2</i> mutation indicates shorter survival in men with prostate cancer Posted: 05 Sep 2010 05:00 PM PDT Men with prostate cancer who carry a deleterious germline mutation in the breast cancer 2 gene do not survive as long as prostate cancer patients who are non-carriers, UK study results show.

Targeted breast cancer strategies needed for Mexican-American women Posted: 05 Sep 2010 05:00 PM PDT Policies that target screening, education, and treatment are needed to address breast cancer disparities among Mexican-origin women in the United States, say researchers.

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