Medical News

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• Neurocognitive deficits evident in adolescents with psychotic-like symptoms
• Siblings of bipolar patients show reduced executive function and memory
• Margarine, red meat, cheese linked to increased risk for IBD
• Percutaneous endovenous intervention reduces post-DVT complications
• GWTG–Stroke mortality model published
• Novel PSA test detects ‘undetectable’ antigen levels post-prostatectomy
• Less pelvic lymph node dissection, less lymph node metastasis detection
• Novel PSA test detects ‘undetectable’ antigen levels post-prostatectomy
• Less pelvic lymph node dissection, less lymph node metastasis detection
• Relatives of young breast cancer patients at risk for other cancers
• <i>APOE</i> variants determine triglyceride concentrations before and after meals
• Malnutrition and inflammation modify cholesterol-CVD relationship in CKD
• High pulse pressure predicts CV events, mortality and ESRD in Type 1 diabetes
• Dapagliflozin monotherapy effective for improving HbA1c in Type 2 diabetes
• <i>CYP2C19</i>*2 and <i>CYP2C9</i>*3 linked to increased stent thrombosis risk
• BP-lowering shows J-curve effect in CVD but not stroke complications
• Relatives of young breast cancer patients at risk for other cancers
• Surgery offers long-term survival for patients with aggressive prostate cancer
• Potential therapeutic target identified for triple-negative breast cancer
• Antibodies may predict prostate cancer better than PSA test
• Disadvantaged men may benefit most from prostate screening
• Decreased breast cancer rates in Canada coincided with reduced HRT use
• Hormone therapy before prostate BRT may improve urinary function
• Partners of breast cancer patients at risk for severe mood disorders

Neurocognitive deficits evident in adolescents with psychotic-like symptoms Posted: 30 Sep 2010 05:00 PM PDT Adolescents with psychotic-like symptoms have impairments in receptive language, motor function, and executive function/speed of processing, study results show.

Siblings of bipolar patients show reduced executive function and memory Posted: 30 Sep 2010 05:00 PM PDT The unaffected siblings of patients with bipolar disorder show deficits in executive functions and memory relative to mentally healthy individuals without a family history of the condition, researchers have found.

Margarine, red meat, cheese linked to increased risk for IBD Posted: 30 Sep 2010 05:00 PM PDT Individuals with signs and symptoms of inflammatory bowel disease often change their diet before a confirmed diagnosis, say researchers who also found that a high consumption of margarine, red meat, and cheese increases the risk for ulcerative colitis and Crohn's disease.

Percutaneous endovenous intervention reduces post-DVT complications Posted: 29 Sep 2010 05:00 PM PDT Percutaneous endovenous intervention reduces the risk for recurrent venous thromboembolism and post-thrombotic syndrome in patients with acute proximal deep vein thrombosis, US researchers report.

GWTG–Stroke mortality model published Posted: 29 Sep 2010 05:00 PM PDT The Get With The Guidelines–Stroke researchers have developed a "practical bedside tool" to predict mortality in patients admitted to hospital with stroke.

Novel PSA test detects ‘undetectable’ antigen levels post-prostatectomy Posted: 29 Sep 2010 05:00 PM PDT US researchers have developed a novel method to detect serum prostate-specific antigen levels in men who have undergone surgery for prostate cancer.

Less pelvic lymph node dissection, less lymph node metastasis detection Posted: 29 Sep 2010 05:00 PM PDT Analysis of SEER registry data indicates that the rate of pelvic lymph node dissection at radical prostatectomy is decreasing over time, resulting in fewer prostate cancer patients being diagnosed with lymph node metastases.

Novel PSA test detects ‘undetectable’ antigen levels post-prostatectomy Posted: 29 Sep 2010 05:00 PM PDT US researchers have developed a novel method to detect serum prostate-specific antigen levels in men who have undergone surgery for prostate cancer.

Less pelvic lymph node dissection, less lymph node metastasis detection Posted: 29 Sep 2010 05:00 PM PDT Analysis of SEER registry data indicates that the rate of pelvic lymph node dissection at radical prostatectomy is decreasing over time, resulting in fewer prostate cancer patients being diagnosed with lymph node metastases.

Relatives of young breast cancer patients at risk for other cancers Posted: 29 Sep 2010 05:00 PM PDT First-degree relatives of women with very early-onset breast cancer have an increased risk for other cancers, even if they do not carry mutations in the BRCA1 and BRCA2 genes, researchers report.

<i>APOE</i> variants determine triglyceride concentrations before and after meals Posted: 29 Sep 2010 05:00 PM PDT Apolipoprotein E gene polymorphisms are important determinants of triglyceride concentrations, especially in the fasting state, claim researchers.

Malnutrition and inflammation modify cholesterol-CVD relationship in CKD Posted: 29 Sep 2010 05:00 PM PDT Malnutrition and inflammation may obscure the relationship between total cholesterol and cardiovascular disease in patients with chronic kidney disease attributed to hypertension, research indicates.

High pulse pressure predicts CV events, mortality and ESRD in Type 1 diabetes Posted: 29 Sep 2010 05:00 PM PDT High pulse pressure predicts cardiovascular events, mortality, and end stage renal disease in patients with Type 1 diabetes, report researchers.

Dapagliflozin monotherapy effective for improving HbA1c in Type 2 diabetes Posted: 29 Sep 2010 05:00 PM PDT The sodium-glucose cotransporter 2 inhibitor dapagliflozin effectively reduces hyperglycemia in newly diagnosed patients with Type 2 diabetes inadequately controlled on diet and exercise alone, show findings from a phase III trial.

<i>CYP2C19</i>*2 and <i>CYP2C9</i>*3 linked to increased stent thrombosis risk Posted: 29 Sep 2010 05:00 PM PDT Dutch researchers report that patients who carry the CYP2C19*2 or CYP2C9*3 loss-of-function alleles have an increased risk for stent thrombosis after percutaneous coronary intervention.

BP-lowering shows J-curve effect in CVD but not stroke complications Posted: 29 Sep 2010 05:00 PM PDT A study suggests that as blood pressure is lowered a patient's risk for cardiovascular disease complications decreases but then increases with aggressive lowering thus mimicking a J-shaped curve.

Relatives of young breast cancer patients at risk for other cancers Posted: 29 Sep 2010 05:00 PM PDT First-degree relatives of women with very early-onset breast cancer have an increased risk for other cancers, even if they do not carry mutations in the BRCA1 and BRCA2 genes, researchers report.

Surgery offers long-term survival for patients with aggressive prostate cancer Posted: 28 Sep 2010 05:00 PM PDT Radical prostatectomy offers patients with aggressive prostate cancer better long-term survival compared with radiotherapy, US researchers report.

Potential therapeutic target identified for triple-negative breast cancer Posted: 28 Sep 2010 05:00 PM PDT US researchers have identified a potential molecular therapeutic target among patients with triple-negative breast cancer.

Antibodies may predict prostate cancer better than PSA test Posted: 27 Sep 2010 05:00 PM PDT UK researchers have developed a novel method for detecting prostate cancer by scanning blood samples for autoantibodies known to be associated with the development of the disease.

Disadvantaged men may benefit most from prostate screening Posted: 27 Sep 2010 05:00 PM PDT Prostate cancer screening may be of most benefit in communities where disadvantaged men live and work, suggest the results of a US study undertaken within the public health system.

Decreased breast cancer rates in Canada coincided with reduced HRT use Posted: 27 Sep 2010 05:00 PM PDT A decrease in hormone replacement therapy use among Canadian women during a 2-year period coincided with decreased breast cancer incidence, research shows.

Hormone therapy before prostate BRT may improve urinary function Posted: 26 Sep 2010 05:00 PM PDT A short course of neoadjuvant hormonal therapy before brachytherapy for low-risk prostate cancer may reduce the duration of urinary dysfunction in the first year after treatment, report researchers from The Netherlands.

Partners of breast cancer patients at risk for severe mood disorders Posted: 26 Sep 2010 05:00 PM PDT Men whose partners have breast cancer are at increased risk for requiring hospitalization for severe mood disorders, study findings indicate.

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