Medical News

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• Dabigatran superior to warfarin irrespective of INR control
• Watchful waiting markedly less expensive than radical prostatectomy
• Environment plus genotype may best predict prostate cancer outcomes
• Watchful waiting markedly less expensive than radical prostatectomy
• Environment plus genotype may best predict prostate cancer outcomes
• Model predicts response to preoperative breast cancer chemotherapy
• Anti-epileptic drugs may impact statin efficacy
• HDL link to noncardiovascular mortality refuted
• Ablation for Barrett’s esophagus does not impair esophageal motility
• Low fetuin-A linked with macrovascular complications in Type 2 diabetes
• Optimized whole-heart MRCA may accurately rule out CAD
• Benefits of double-dose clopidogrel post-ACS unclear
• Model predicts response to preoperative breast cancer chemotherapy

Dabigatran superior to warfarin irrespective of INR control Posted: 09 Sep 2010 05:00 PM PDT Patients with atrial fibrillation have fewer strokes and bleeding events when taking dabigatran than when treated with warfarin, even if their international normalized ratios are strictly controlled, shows further analysis of the RE-LY study.

Watchful waiting markedly less expensive than radical prostatectomy Posted: 09 Sep 2010 05:00 PM PDT Watchful waiting with active surveillance dramatically reduces prostate cancer costs compared with active surgical treatment, say US researchers.

Environment plus genotype may best predict prostate cancer outcomes Posted: 09 Sep 2010 05:00 PM PDT Genetic risk factors may best be able to predict poor outcomes in prostate cancer patients when socioeconomic and lifestyle factors are also taken into account, report US researchers.

Watchful waiting markedly less expensive than radical prostatectomy Posted: 09 Sep 2010 05:00 PM PDT Watchful waiting with active surveillance dramatically reduces prostate cancer costs compared with active surgical treatment, say US researchers.

Environment plus genotype may best predict prostate cancer outcomes Posted: 09 Sep 2010 05:00 PM PDT Genetic risk factors may best be able to predict poor outcomes in prostate cancer patients when socioeconomic and lifestyle factors are also taken into account, report US researchers.

Model predicts response to preoperative breast cancer chemotherapy Posted: 09 Sep 2010 05:00 PM PDT Researchers have devised a model to predict how breast cancer patients will respond to preoperative chemotherapy, based on the expression of biological markers including Ki-67, estrogen receptor, and progesterone receptor expression, as well as duration of preoperative therapy.

Anti-epileptic drugs may impact statin efficacy Posted: 09 Sep 2010 05:00 PM PDT Physicians should be alert for reduced efficacy of statin treatment in patients with epilepsy being treated with commonly used older-generation antiepileptic drugs, warn researchers.

HDL link to noncardiovascular mortality refuted Posted: 09 Sep 2010 05:00 PM PDT Raising patients' levels of high-density lipoprotein cholesterol should not increase their risk for noncardiovascular mortality, conclude the authors of a meta-analysis.

Ablation for Barrett’s esophagus does not impair esophageal motility Posted: 09 Sep 2010 05:00 PM PDT Ablative techniques used to treat Barrett's esophagus do not impair esophageal motility, but may decrease the ability of the esophagus to detect acidity, researchers in the UK have shown.

Low fetuin-A linked with macrovascular complications in Type 2 diabetes Posted: 09 Sep 2010 05:00 PM PDT A low serum concentration of fetuin-A is a significant independent predictor of reduced ankle-brachial index in patients with Type 2 diabetes, show study results.

Optimized whole-heart MRCA may accurately rule out CAD Posted: 09 Sep 2010 05:00 PM PDT Japanese researchers suggest that non-contrast enhanced whole-heart magnetic resonance coronary angiography may be a useful tool for excluding significant coronary artery disease in chest pain patients suspected to have the condition.

Benefits of double-dose clopidogrel post-ACS unclear Posted: 09 Sep 2010 05:00 PM PDT Results from the CURRENT-OASIS 7 study suggest that neither a double-dose of clopidogrel in the first week, nor high-dose aspirin, after acute coronary syndrome reduces the risk for cardiovascular events compared with standard doses of each drug in patients referred for invasive treatment.

Model predicts response to preoperative breast cancer chemotherapy Posted: 09 Sep 2010 05:00 PM PDT Researchers have devised a model to predict how breast cancer patients will respond to preoperative chemotherapy, based on the expression of biological markers including Ki-67, estrogen receptor, and progesterone receptor expression, as well as duration of preoperative therapy.

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