Medical News

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• Japanese schizophrenia patients at increased risk for metabolic syndrome
• Bipolar disorder linked to reduced socio-economic status
• GI scintiscan better as single test for GER detection in infant wheezers
• Elevated FVIII, platelets reverse anticoagulant effect of protamine
• Compression stockings have little effect on post-stroke DVT risk
• Robot-assisted radical prostatectomy offers effective 5-year cancer control
• Functional limitations affect mortality of breast cancer survivors
• Robot-assisted radical prostatectomy offers effective 5-year cancer control
• Statins reduce markers of inflammation
• LDL cholesterol main lipid determinant of atherosclerosis
• Sulfonylurea CV risk in MI patients with diabetes not undergoing emergent PCI
• Mild anemia associated with micro- and macroangiopathies in Type 2 diabetes
• Supplementing HF education with self-management advice does not improve outcomes
• Subclinical hypothyroidism may increase CHD event, mortality risk
• Functional limitations affect mortality of breast cancer survivors
• High-grade PIN at initial biopsy increases risk for subsequent prostate cancer
• MCM7 inhibition holds promise for treatment of aggressive prostate cancer
• Variants at 19p13 loci alter breast cancer risk in <i>BRCA1</i> mutation carriers
• Accurate treatment triggers needed for prostate cancer patients on surveillance
• Radiotherapy linked to complications after mastectomy with reconstruction
• Age, time to PSA failure indicate PSA bounce rather than recurrence
• HRQoL dysfunction after prostate treatment influences bother, distress
• Sexual problems uncommon after surgery for early stage breast cancer

Japanese schizophrenia patients at increased risk for metabolic syndrome Posted: 23 Sep 2010 05:00 PM PDT Japanese patients with schizophrenia are at increased risk for the metabolic syndrome, reflecting a similar association in Western patients with the psychotic disorder, study results show.

Bipolar disorder linked to reduced socio-economic status Posted: 23 Sep 2010 05:00 PM PDT Results from a Norwegian study suggest that, overall, individuals with bipolar disorder have lower socio-economic status than the general population, despite having similar education levels.

GI scintiscan better as single test for GER detection in infant wheezers Posted: 23 Sep 2010 05:00 PM PDT Gastro-intestinal scintiscan performs better than 24-hour pH monitoring for detection of gastroesophageal reflux in infants with wheeze, show study results.

Elevated FVIII, platelets reverse anticoagulant effect of protamine Posted: 22 Sep 2010 05:00 PM PDT The anticoagulant effect of protamine occurs via the propagation of thrombin generation, but may be attenuated in the presence of platelets or elevated factor VIII concentrations, research shows.

Compression stockings have little effect on post-stroke DVT risk Posted: 22 Sep 2010 05:00 PM PDT Patients who are immobilized after a stroke are less likely to suffer deep vein thrombosis if they wear thigh-length, rather than below-knee-length, compression stockings, report the CLOTS investigators.

Robot-assisted radical prostatectomy offers effective 5-year cancer control Posted: 22 Sep 2010 05:00 PM PDT Prostate cancer patients treated with robot-assisted radical prostatectomy can expect low rates of biochemical recurrence after 5 years, US study findings show.

Functional limitations affect mortality of breast cancer survivors Posted: 22 Sep 2010 05:00 PM PDT Functional limitations following initial breast cancer treatment are associated with reduced overall and competing-cause survival, but not breast cancer–specific survival, study findings indicate.

Robot-assisted radical prostatectomy offers effective 5-year cancer control Posted: 22 Sep 2010 05:00 PM PDT Prostate cancer patients treated with robot-assisted radical prostatectomy can expect low rates of biochemical recurrence after 5 years, US study findings show.

Statins reduce markers of inflammation Posted: 22 Sep 2010 05:00 PM PDT Statin therapy is associated with significant reductions in inflammatory parameters such as white blood cell count and C-reactive protein, an analysis of US population data indicates.

LDL cholesterol main lipid determinant of atherosclerosis Posted: 22 Sep 2010 05:00 PM PDT Low-density lipoprotein cholesterol appears to be the main lipid driver of atherosclerosis, show findings from the Multiethnic Study of Atherosclerosis.

Sulfonylurea CV risk in MI patients with diabetes not undergoing emergent PCI Posted: 22 Sep 2010 05:00 PM PDT Several, but not all, sulfonylureas are associated with increased cardiovascular risk compared with metformin therapy in patients with diabetes who do not undergo emergent percutaneous coronary intervention after myocardial infarction, research suggests.

Mild anemia associated with micro- and macroangiopathies in Type 2 diabetes Posted: 22 Sep 2010 05:00 PM PDT Mild anemia is commonly found in patients with Type 2 diabetes and is associated with micro- and macroangiopathies, Japanese researchers report.

Supplementing HF education with self-management advice does not improve outcomes Posted: 22 Sep 2010 05:00 PM PDT US researchers suggest there is no benefit to supplementing the standard educational materials given to patients with mild to moderate heart failure with self-management counselling.

Subclinical hypothyroidism may increase CHD event, mortality risk Posted: 22 Sep 2010 05:00 PM PDT Patients with subclinical hypothyroidism may have an increased risk for coronary heart disease events and mortality, especially if their thyroid-stimulating hormone levels are 10 mIU/l or more, researchers report.

Functional limitations affect mortality of breast cancer survivors Posted: 22 Sep 2010 05:00 PM PDT Functional limitations following initial breast cancer treatment are associated with reduced overall and competing-cause survival, but not breast cancer–specific survival, study findings indicate.

High-grade PIN at initial biopsy increases risk for subsequent prostate cancer Posted: 21 Sep 2010 05:00 PM PDT Men diagnosed with high-grade multifocal or bilateral prostatic intraepithelial neoplasia after their first prostate biopsy are at significant risk for subsequently developing prostate cancer, report US researchers.

MCM7 inhibition holds promise for treatment of aggressive prostate cancer Posted: 21 Sep 2010 05:00 PM PDT US study results indicate that inhibiting the expression of the minichromosome complex maintenance component 7 cell protein could lead to successful treatment of aggressive prostate cancer.

Variants at 19p13 loci alter breast cancer risk in <i>BRCA1</i> mutation carriers Posted: 21 Sep 2010 05:00 PM PDT Researchers have found that single nucleotide polymorphisms located on chromosome 19, at 19p13, modify breast cancer risk in BRCA1 mutation carriers and are associated with hormone receptor- negative breast cancer in the general population.

Accurate treatment triggers needed for prostate cancer patients on surveillance Posted: 20 Sep 2010 05:00 PM PDT The standard prostate-specific antigen measurements used to evaluate low-risk prostate cancer patients on watchful waiting programs may result in many being unnecessarily triggered for active treatment, says a Canadian research team.

Radiotherapy linked to complications after mastectomy with reconstruction Posted: 20 Sep 2010 05:00 PM PDT Nearly half of women who have radiation therapy following a mastectomy with immediate breast reconstruction suffer complications that require further surgery, study findings indicate.

Age, time to PSA failure indicate PSA bounce rather than recurrence Posted: 19 Sep 2010 05:00 PM PDT Age and time to prostate-specific antigen failure best distinguish between a benign rise in PSA and one that could indicate disease recurrence or progression, report Canadian researchers.

HRQoL dysfunction after prostate treatment influences bother, distress Posted: 19 Sep 2010 05:00 PM PDT Health-related quality of life dysfunction following treatment for prostate cancer is strongly associated with a patient's subjective distress, report US researchers.

Sexual problems uncommon after surgery for early stage breast cancer Posted: 19 Sep 2010 05:00 PM PDT Women with early stage breast cancer report few sexual problems during the first 2 years after breast conserving surgery or mastectomy, US research shows.

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