Medical News

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• <i>In utero</i> smoke exposure reduces asthma treatment response in children
• Glutamate and dopamine relationship altered in patients at ultra-high risk for psychosis
• Asian bipolar patients at increased risk for metabolic syndrome
• High-grade PIN at initial biopsy increases risk for subsequent prostate cancer
• MCM7 inhibition holds promise for treatment of aggressive prostate cancer
• Variants at 19p13 loci alter breast cancer risk in <i>BRCA1</i> mutation carriers
• Adding fenofibric acid to statin therapy shows metabolic benefits
• Vitamin D metabolites show differential association with lipoproteins
• NT-proBNP predicts silent myocardial ischemia in Type 2 diabetes
• Cardiac troponin T elevations common in Type 2 diabetes
• Can ECG screening prevent sudden death in athletes?
• Suboptimal NSTE ACS treatment often arises from underestimation of risk

<i>In utero</i> smoke exposure reduces asthma treatment response in children Posted: 22 Sep 2010 05:00 PM PDT Results from a US study suggest that in utero exposure to tobacco smoke in associated with a reduced response to treatment with inhaled corticosteroids in children with asthma.

Glutamate and dopamine relationship altered in patients at ultra-high risk for psychosis Posted: 22 Sep 2010 05:00 PM PDT Results from a UK study show that the relationship between hippocampal glutamate levels and striatal dopamine function in patients at ultra-high risk for psychosis differs from that in mentally healthy individuals.

Asian bipolar patients at increased risk for metabolic syndrome Posted: 22 Sep 2010 05:00 PM PDT Results from a Korean study show that Asian patients with bipolar disorder are at increased risk for the metabolic syndrome.

High-grade PIN at initial biopsy increases risk for subsequent prostate cancer Posted: 21 Sep 2010 05:00 PM PDT Men diagnosed with high-grade multifocal or bilateral prostatic intraepithelial neoplasia after their first prostate biopsy are at significant risk for subsequently developing prostate cancer, report US researchers.

MCM7 inhibition holds promise for treatment of aggressive prostate cancer Posted: 21 Sep 2010 05:00 PM PDT US study results indicate that inhibiting the expression of the minichromosome complex maintenance component 7 cell protein could lead to successful treatment of aggressive prostate cancer.

Variants at 19p13 loci alter breast cancer risk in <i>BRCA1</i> mutation carriers Posted: 21 Sep 2010 05:00 PM PDT Researchers have found that single nucleotide polymorphisms located on chromosome 19, at 19p13, modify breast cancer risk in BRCA1 mutation carriers and are associated with hormone receptor- negative breast cancer in the general population.

Adding fenofibric acid to statin therapy shows metabolic benefits Posted: 21 Sep 2010 05:00 PM PDT The addition of fenofibric acid to statin therapy reduces the prevalence of the metabolic syndrome, primarily by improving lipid parameters, US researchers report.

Vitamin D metabolites show differential association with lipoproteins Posted: 21 Sep 2010 05:00 PM PDT Blood levels of the active and storage forms of vitamin D show differential associations with blood levels of lipids and lipoproteins, research demonstrates.

NT-proBNP predicts silent myocardial ischemia in Type 2 diabetes Posted: 21 Sep 2010 05:00 PM PDT The N-terminal fragment of pro-brain natriuretic peptide can predict silent myocardial ischemia in patients with Type 2 diabetes independently of microalbuminuria, a study suggests.

Cardiac troponin T elevations common in Type 2 diabetes Posted: 21 Sep 2010 05:00 PM PDT Elevated circulating levels of cardiac troponinT, measured using a sensitive assay, are common in patients with Type 2 diabetes, researchers report.

Can ECG screening prevent sudden death in athletes? Posted: 21 Sep 2010 05:00 PM PDT The expense and efficacy of implementing an electrocardiographic screening program to prevent sudden death in athletes has come under scrutiny in a debate in the British Medical Journal.

Suboptimal NSTE ACS treatment often arises from underestimation of risk Posted: 21 Sep 2010 05:00 PM PDT A Canadian study suggests that physicians often underestimate the risk for adverse outcomes among patients with non-ST-elevation acute coronary syndromes and therefore fail to prescribe guideline-recommended evidence-based medical treatments as necessary.

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