Medical News

Moxifloxacin ‘could shorten TB treatment by months’ Posted: 06 Apr 2009 05:00 PM PDT The antibiotic moxifloxacin is active against tuberculosis and could potentially shorten the duration of treatment by several months, a phase II study has shown.

Effector T cells source of IL-10 during flu virus infection Posted: 06 Apr 2009 05:00 PM PDT Antiviral effector T cells are the primary source of interleukin-10 produced in the respiratory tract during influenza infection, research shows.

Patient knowledge of COPD low despite symptoms Posted: 06 Apr 2009 05:00 PM PDT Patients with chronic obstructive pulmonary disease often know more about, and are much better treated for, underlying comorbidities than COPD, US research shows.

Risk factors for suicide after psychiatric discharge identified Posted: 06 Apr 2009 05:00 PM PDT Mental health patients face a significantly increased risk for suicide within a month of discharge from psychiatric hospital, particularly those with a mood disorder or a history of self-harm, research shows.

Comorbid SUD affects clinical presentation of bipolar disorder patients Posted: 06 Apr 2009 05:00 PM PDT Researchers have found that comorbid substance use disorder significantly impairs bipolar disorder patients' social functioning and increases their chances of having bipolar II disorder.

Shock tactics do not prompt smokers with lung disease to quit Posted: 05 Apr 2009 05:00 PM PDT Confronting smokers with evidence of their habit's destructive effects on their lungs does not assist their efforts to quit smoking, say Dutch researchers.

Risk factors for suicide after psychiatric hospital discharge identified Posted: 05 Apr 2009 05:00 PM PDT Mental health patients face a significantly increased risk of suicide within a month of discharge from psychiatric hospital, particularly those with mood disorders or a history of self harm, research shows.

Pollution from oil refineries increases risk of childhood respiratory diseases Posted: 05 Apr 2009 05:00 PM PDT Children who are exposed to airborne pollution from oil refineries face an increased risk of asthma, respiratory symptoms and poor lung function, study findings suggest.

Broccoli sprouts may suppress ulcer bug infection Posted: 05 Apr 2009 05:00 PM PDT Eating broccoli sprouts may help suppress infection with a stomach bug, called Helicobacter pylori, which causes ulcers, gastritis and stomach cancer, study results suggest.

Six quantitative trait loci identified for fibrin clot phenotypes Posted: 05 Apr 2009 05:00 PM PDT Researchers have found least six chromosomal regions linked to fibrin clot phenotype and have revealed that genetic factors significantly contribute to variation in clot structure and function.

Anticoagulation risks may outweigh benefits after carotid artery dissection Posted: 05 Apr 2009 05:00 PM PDT Results from a large prospective study indicate that the risk for recurrent ischemic events in patients with carotid artery dissection is little influenced by whether they receive anticoagulation or antiplatelet treatment.

COPD patients ‘exhibit accelerated aging’ Posted: 05 Apr 2009 05:00 PM PDT Patients with chronic obstructive pulmonary disease tend to exhibit shortened telomeres, a feature indicative of accelerated aging, French researchers have shown.

Breath sounds analysis shows promise for monitoring lung function Posted: 05 Apr 2009 05:00 PM PDT Analyzing breath sounds may be a valuable alternative to spirometry for assessing lung function in children with asthma, Japanese experts believe.

PBSI acceptable, well-tolerated for early breast cancer radiotherapy Posted: 05 Apr 2009 05:00 PM PDT 103Palladium permanent breast seed implant is a safe and tolerable partial breast irradiation technique for treatment of early stage breast cancer, clinical trial results show.

Breast cancer more common in women with high-density breasts Posted: 05 Apr 2009 05:00 PM PDT Breast cancer is more frequent but mortality is reduced in women with high- than low-density breasts, a Danish study shows.

Frizzled complexes mediate prostate cancer androgen receptor cuts Posted: 05 Apr 2009 05:00 PM PDT Androgen receptor downregulation in prostate cancer by secreted Frizzled-related protein-1 may be mediated by the formation of complexes with Frizzled receptors, say scientists.

Postmenopausal hormone therapy use may decrease diabetes risk Posted: 05 Apr 2009 05:00 PM PDT A study has found that hormone therapy use may decrease the incidence of diabetes in postmenopausal women, with the risk decrease largest in women who use HT for longer than 2.5 years.

Endocrine and stress-related factors linked to increased perimenopausal cortisol levels Posted: 05 Apr 2009 05:00 PM PDT A study has found that increased overnight cortisol levels during the menopausal transition are associated with MT- and stress-related endocrine factors, but not with symptom severity and perceived or social stressors.

Red meat consumption associated with increased risk for endometrial cancer Posted: 05 Apr 2009 05:00 PM PDT Study results suggest an association between dietary habits and endometrial cancer risk, with a diet poor in vegetables and high in red meat potentially increasing this risk.

Pemetrexed effective treatment for recurrent platinum-resistant ovarian cancer Posted: 05 Apr 2009 05:00 PM PDT A phase II Gynecologic Oncology Group trial has found that pemetrexed—an antifolate antineoplastic agent that disrupts folate-dependent cell replication metabolic processes—is sufficiently active in the treatment of recurrent platinum-resistant ovarian cancer to warrant further investigation.

Frameless IUD has comparable clinical performance to the TCu380A Posted: 05 Apr 2009 05:00 PM PDT A study has found that the frameless copper intrauterine device —designed to reduced side effects related to the frame of conventional IUDs—has more insertion failures, expulsions, and pregnancies in the first year than TCu380A, but shows favorable cumulative 8-year outcomes overall.

DMPA-SC formulation provides comparable efficacy and safety to DMPA-IM Posted: 05 Apr 2009 05:00 PM PDT Phase III study results show that subcutaneous injection of depot medroxyprogesterone acetate is an effective and well-tolerated contraceptive option, providing comparable efficacy and bone mineral density safety to intramuscular DMPA formulations.

Favorable obstetric outcome when smoking ceased before 15 weeks’ gestation Posted: 05 Apr 2009 05:00 PM PDT A study has found that stopping smoking before 15 weeks' gestation results in rates of spontaneous preterm births and small for gestational age infants similar to those in nonsmokers.

Proteinuria not useful as a predictor of complications during pre-eclampsia Posted: 05 Apr 2009 05:00 PM PDT A study has found that the measure of proteinuria is a poor predictor of either maternal of fetal complications in women with pre-eclampsia.

Cardioprotective effect of EPA greatest in dyslipidemic individuals with IGM Posted: 05 Apr 2009 05:00 PM PDT Results from the JELIS trial show that supplementation with eicosapentaenoic acid reduces coronary artery disease incidence to a greater degree in hypercholesterolemic individuals with impaired glucose metabolism than in those with normoglycemia.

Nordic walking program improves BMI, lipids, VO2max in women Posted: 05 Apr 2009 05:00 PM PDT Researchers report that a 12-week program of Nordic Walking improves the body mass index and lipid profile of pre- and perimenopausal women, and the VO2max of pre-, peri-, and postmenopausal women.

Depression linked to worse outcomes in HF Posted: 05 Apr 2009 05:00 PM PDT People with a history of depression at hospitalization for heart failure fare worse than those without prior depression, reveal OPTIMIZE-HF registry data.

Metabolic syndrome impairs coronary collateral growth in CAD Posted: 05 Apr 2009 05:00 PM PDT A study shows that patients with coronary artery disease who have the metabolic syndrome have less developed coronary collaterals than those without the metabolic syndrome, an observation that may explain the poor clinical outcome in patients with the metabolic syndrome.

Nicorandil prevents slow coronary reflow but has no long-term clinical benefit Posted: 05 Apr 2009 05:00 PM PDT A bolus of 6 mg nicorandil administered intravenously immediately prior to percutaneous coronary intervention prevented slow coronary reflow phenomenon in patients with acute coronary syndromes and stable angina alike, without adverse effects, reports a Japanese team.

Depression linked to worse outcomes in HF Posted: 05 Apr 2009 05:00 PM PDT People with a history of depression at hospitalization for heart failure fare worse than those without prior depression, reveal OPTIMIZE-HF registry data.

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