Medical News

Glucocorticoid sensitivity may mediate asthma–stress link Posted: 23 Apr 2009 05:00 PM PDT Psychological stress appears to be involved in the development and severity of asthma, effects that may be mediated by cortisol overload and compensatory resistance to glucocorticoids, say researchers.

Prostaglandin receptor variation predicts pediatric asthma risk Posted: 23 Apr 2009 05:00 PM PDT Researchers have identified a polymorphism in the prostaglandin D receptor gene that appears to protect against the risk for asthma in European children.

Fewer exacerbations needing steroids with single inhalers, but more data needed Posted: 23 Apr 2009 05:00 PM PDT A combination of formoterol and budesonide in a single inhaler failed to reduce asthma exacerbations requiring hospitalization in comparison with standard treatment, a review shows.

Clue to lithium benefits in bipolar patients Posted: 23 Apr 2009 05:00 PM PDT Researchers have identified a possible mechanism for how lithium stabilizes the mood of patients with bipolar disorder, a finding that may lead to the development of more effective drugs to treat the condition.

Circadian interventions bolster antidepressant responses in bipolar disorder Posted: 23 Apr 2009 05:00 PM PDT Adding a combination of noninvasive circadian-related interventions to standard medication in patients with bipolar disorder accelerates, augments and sustains antidepressant responses, say US researchers.

Pioglitazone enhances antipsoriatic effect of acitretin Posted: 23 Apr 2009 05:00 PM PDT Pioglitazone appears to be an effective antipsoriatic drug and a convenient and well-tolerated option to combine with acitretin, research suggests.

Diabetes and hypertension risk increased in women with psoriasis Posted: 23 Apr 2009 05:00 PM PDT Women with psoriasis have an increased risk of diabetes and hypertension, researchers have found.

Sequential local therapy shows rapid response in psoriasis vulagris patients Posted: 23 Apr 2009 05:00 PM PDT Sequential treatment with mometasone furoate and salicyclic acid followed by mometasone furoate alone is an "excellent option" for patients with psoriasis vulgaris, say researchers.

Increased cancer risk for hospitalised psoriasis patients Posted: 23 Apr 2009 05:00 PM PDT Psoriasis patients have an increased risk of cancer, say researchers who found that patients with multiple hospitalisations for the skin disease were particularly at increased risk of developing oesophageal and skin cancers.

Symptom relief is most important treatment issue for ulcerative colitis patients Posted: 22 Apr 2009 05:00 PM PDT Patients with ulcerative colitis place more importance on the effectiveness of their medications for providing symptom relief than on other considerations, such as dosing and the frequency of treatment, Canadian survey results show.

Bipolar depression symptoms ‘more common during menopause’ Posted: 22 Apr 2009 05:00 PM PDT Women with bipolar disorder who are going through the menopause are more likely to experience depressive symptoms than men or younger women with the disorder, results of a US study show.

Emotional wellbeing affects exercise patterns in breast cancer survivors Posted: 22 Apr 2009 05:00 PM PDT The amount of physical exercise undertaken by breast cancer survivors is closely tied to their emotional wellbeing, research shows.

Vitamin D linked to asthma severity in children Posted: 22 Apr 2009 05:00 PM PDT Low levels of vitamin D may increase asthma severity in children, research suggests.

CKD, OAC raise risk for poor PCI outcome Posted: 22 Apr 2009 05:00 PM PDT Oral anticoagulation users with chronic kidney disease are at high risk for major bleeding and death following percutaneous coronary intervention artery stenting, researchers caution in the journal Chest.

Statins reduce risk for initial and recurrent stroke Posted: 22 Apr 2009 05:00 PM PDT The results of a large meta-analysis show that the use of statins to lower cholesterol reduces the risk for both initial and recurrent stroke.

Local anesthetic added to nerve block reduces prostate biopsy pain Posted: 22 Apr 2009 05:00 PM PDT During transrectal ultrasonography-guided prostate biopsy, adding a local anesthetic creamto periprostatic nerve block is more effective than nerve block alone in reducing pain and discomfort, Italian study findings indicate.

No increase in prostate cancer risk with late-onset hypogonadism Posted: 22 Apr 2009 05:00 PM PDT Although late-onset hypogonadism can be treated effectively and is not associated with increased prostate cancer risk, say US scientists.

Obesity impact on breast cancer prognosis only for HRT patients Posted: 22 Apr 2009 05:00 PM PDT The impact of obesity on postmenopausal breast cancer outcome may be restricted to women who have used hormone replacement therapy, study findings suggest.

Local anesthetic added to nerve block reduces prostate biopsy pain Posted: 22 Apr 2009 05:00 PM PDT During transrectal ultrasonography-guided prostate biopsy, adding a local anesthetic creamto periprostatic nerve block is more effective than nerve block alone in reducing pain and discomfort, Italian study findings indicate.

No increase in prostate cancer risk with late-onset hypogonadism Posted: 22 Apr 2009 05:00 PM PDT Although late-onset hypogonadism can be treated effectively and is not associated with increased prostate cancer risk, say US scientists.

Individuals with high hs-CRP have low plasma levels of omega-3 fatty acids Posted: 22 Apr 2009 05:00 PM PDT Healthy individuals with high levels of high-sensitivity C-reactive protein have low plasma levels of omega-3 fatty acids, report researchers in the European Journal of Clinical Nutrition.

Pitavastatin treatment effective for improving lipids post AMI Posted: 22 Apr 2009 05:00 PM PDT Results from LAMIS presented at the Angioplasty Summit-TCT Asia Pacific show that routine administration of pitavastatin to patients following acute myocardial infarction significantly improves lipid levels and inflammatory markers.

Voglibose may help prevent development of Type 2 diabetes Posted: 22 Apr 2009 05:00 PM PDT The α-glucosidase inhibitor voglibose reduces the incidence of Type 2 diabetes in Japanese individuals with impaired glucose tolerance when combined with lifestyle modification of diet and physical activity, show study results.

Women with psoriasis have increased risk for diabetes and hypertension Posted: 22 Apr 2009 05:00 PM PDT Women with the skin condition psoriasis have an increased risk for diabetes and hypertension, report researchers from the Nurses' Health Study.

MERLIN–TIMI analysis underlines broader potential of ranolazine Posted: 22 Apr 2009 05:00 PM PDT A prespecified analysis of the MERLIN-TIMI trial demonstrates anti-anginal benefits of ranolazine in a broader group of angina patients than previously studied, say the investigators.

Clinical information better than BP alone to predict future hypertension Posted: 22 Apr 2009 05:00 PM PDT Use of a model based on readily available clinical information is better able to predict the development of hypertension than one based on blood pressure alone, US researchers report.

Obesity impact on breast cancer prognosis only for HRT patients Posted: 22 Apr 2009 05:00 PM PDT The impact of obesity on postmenopausal breast cancer outcome may be restricted to women who have used hormone replacement therapy, study findings suggest.

AR signature may improve hormone-resistant prostate cancer therapy Posted: 21 Apr 2009 05:00 PM PDT A novel transcription-based activity signature is able to detect androgen receptor activity within individual prostate cancer specimens, say US scientists whose findings may help to improve care for patients with castration-resistant tumors.

Medical costs increased by lymphedema following breast cancer Posted: 21 Apr 2009 05:00 PM PDT Breast cancer-related lymphedema is associated with full axillary node dissection, chemotherapy, and geographical region, a study shows.

IMRT for breast cancer may reduce radiation-induced cardiac mortality Posted: 21 Apr 2009 05:00 PM PDT Aperture-based multifield intensity-modulated radiotherapy for left-sided breast cancer reduces the maximal radiation dose to the left ventricle, and may therefore decrease cardiac mortality, study analysis shows.

Comprehension of prostate cancer terms poor among low-income patients Posted: 20 Apr 2009 05:00 PM PDT Prostate cancer knowledge and comprehension of prostate cancer terms is poor in low-income, under-served populations, potentially hampering informed consent and the accurate measurement of outcomes, warn US investigators.

Percentage of positive cores dictates prostate cancer EBRT outcomes Posted: 20 Apr 2009 05:00 PM PDT Biochemical failure in intermediate-risk prostate cancer patients receiving dose-escalation external beam radiotherapy is most likely in those with a percentage of positive cores ≥50, US researchers have discovered.

Breast radiotherapy outcome predicted by chest wall, lung radiation dose Posted: 20 Apr 2009 05:00 PM PDT Outcome, in terms of pain but not cosmesis, following accelerated partial breast intensity-modulated radiotherapy is dependent on treatment planning parameters, a phase II study shows.

Agent Orange exposure linked to increased prostate cancer progression risk Posted: 19 Apr 2009 05:00 PM PDT Prostate cancer patients exposed to Agent Orange have an increased risk for biochemical progression and short prostate-specific antigen doubling time after radical prostatectomy, conclude US researchers.

False-positive rate of breast NCB is extremely low Posted: 19 Apr 2009 05:00 PM PDT True false-positive diagnoses following pre-operative breast needle core biopsy (NCB) are exceedingly rare, a large UK study shows.

Breast cancer treatment unaffected by homeopathy Posted: 19 Apr 2009 05:00 PM PDT Use of homeopathy to relieve side effects of cancer treatment is unlikely to cause adverse effects or interfere with treatment efficacy, a review of preliminary research shows.

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