Medical News

Cigarettes worsen inflammatory response to COPD bacterial exacerbations Posted: 16 Apr 2009 05:00 PM PDT Cigarette smoke exacerbates the inflammatory response to a bacterial challenge through altered inflammatory mediator expression, research shows.

New TB vaccine ‘immunogenic’ in latent infection Posted: 16 Apr 2009 05:00 PM PDT A potent new tuberculosis vaccine has shown encouraging signs of safety and immunogenicity in a phase I study of latently infected individuals, paving the way for further research in TB-endemic areas.

Endurance athletes show airway hyper-responsiveness Posted: 16 Apr 2009 05:00 PM PDT Competitive athletes who swim or exercise in cold air have signs of airway remodeling and hyper-responsiveness, study findings show.

Subtle symptom differences between unipolar and bipolar depression Posted: 16 Apr 2009 05:00 PM PDT Depression in patients with bipolar disorder is associated with more frequent suicide ideation and psychomotor disturbance than is experienced by patients with major depressive disorder, research suggests.

Schizophrenia patients face reduced fertility Posted: 16 Apr 2009 05:00 PM PDT Patients with schizophrenia, but not affective psychosis, have reduced biologic fertility persisting into the second generation that is partly explained by marital status, study findings indicate.

Etanercept shows efficacy for severe, recalcitrant psoriasis Posted: 16 Apr 2009 05:00 PM PDT Etanercept has shown some efficacy for the treatment of severe, recalcitrant psoriasis in a retrospective study of patients at a Greek hospital.

Palmoplantar psoriasis shows some resistance to topical therapies Posted: 16 Apr 2009 05:00 PM PDT Patients with localized forms of psoriasis are likely to need multiple systemic agents to treat their condition, researchers suggest.

Pulsed dye laser therapy effective for nail psoriasis Posted: 16 Apr 2009 05:00 PM PDT Pulse dye laser therapy seems to be effective for nail psoriasis, improving both nail matrix and nail bed involvement, researchers report.

Dermatologic patients need better basic drug information Posted: 16 Apr 2009 05:00 PM PDT Researchers have highlighted the need for better information about disease and topical treatment to be given to dermatologic outpatients.

Passive smoking in cars linked to hayfever and wheezing in children Posted: 15 Apr 2009 05:00 PM PDT Children who are regularly exposed to second-hand tobacco smoke when travelling by car have significantly higher rates of hayfever and wheezing than those without such exposure, results of an Irish study show.

Subtle symptom differences between bipolar and unipolar depression Posted: 15 Apr 2009 05:00 PM PDT Depression in patients with bipolar disorder is associated with more frequent thoughts of suicide and disturbance in mental processes that control movement, called psychomotor disturbance, than that in patients with major depressive disorder, research suggests.

Even light smoking ill advised in inflammatory bowel disease patients Posted: 15 Apr 2009 05:00 PM PDT Even light smoking aggravates the condition of patients with the inflammatory bowel condition Crohn's disease, researchers have found.

Fertility and pregnancy outcome worries plague inflammatory bowel disease patients Posted: 15 Apr 2009 05:00 PM PDT People with inflammatory bowel disease often remain childless because of concerns about their condition, results of an Australian survey show.

VTE risk highlighted for prostate surgery patients Posted: 15 Apr 2009 05:00 PM PDT Prolonged thromboprophylaxis may be warranted in men undergoing protate surgery, say German researchers who found venous thromboembolism is common more than a week after radical prostatectomy.

Two SNPs linked to stroke risk Posted: 15 Apr 2009 05:00 PM PDT Research published in the New England Journal of Medicine reveals that two previously unsuspected common single-nucleotide polymorphisms on chromosome 12p13 are associated with an increased risk for stroke.

VTE risk highlighted for prostate surgery patients Posted: 15 Apr 2009 05:00 PM PDT Prolonged thromboprophylaxis may be warranted in men undergoing protate surgery, say German researchers who found venous thromboembolism is common more than a week after radical prostatectomy.

Circulating DNA linked to CTCs in breast cancer Posted: 15 Apr 2009 05:00 PM PDT In breast cancer patients, high levels of circulating total/methylated DNA are associated with large numbers of circulating tumor cells, which may point to a more aggressive tumor biology, say Belgian researchers.

Reconstruction delay unnecessary for postmastectomy radiotherapy Posted: 15 Apr 2009 05:00 PM PDT Women who receive radiotherapy after reconstructive surgery do not have a higher rate of major complications than those who delay the cosmetic procedure, US researchers have found.

VTE risk highlighted for prostate surgery patients Posted: 15 Apr 2009 05:00 PM PDT Prolonged thromboprophylaxis may be warranted in men undergoing protate surgery, say German researchers who found venous thromboembolism is common more than a week after radical prostatectomy.

Replacing trans fats with vegetable oil improves CV risk profile Posted: 15 Apr 2009 05:00 PM PDT Consuming unmodified vegetable oil in place of partially hydrogenated fats may be an effective dietary approach to improving blood lipid and lipoprotein levels and hence reducing cardiovascular risk, US researchers believe.

Lipid control improving among French adults Posted: 15 Apr 2009 05:00 PM PDT The prevalence of dyslipidemia among the French population has steadily declined over the past 10 years, an encouraging trend that is linked with the greater use of lipid-lowering drugs, according to a study.

DIAD: Routine CAD screening in diabetes patients ‘ineffective’ Posted: 15 Apr 2009 05:00 PM PDT Screening people with Type 2 diabetes for asymptomatic coronary artery disease does not identify individuals who are at relatively greater risk than others, according to results of the DIAD study.

DIAD: Routine CAD screening in diabetes patients ‘ineffective’ Posted: 15 Apr 2009 05:00 PM PDT Screening people with Type 2 diabetes for asymptomatic coronary artery disease does not identify individuals who are at relatively greater risk than others, according to results of the DIAD study.

Modifiable HF risk differs by race in elderly Posted: 15 Apr 2009 05:00 PM PDT Incident heart failure is common and associated with poor prognosis in elderly people, say researchers who also identified race-related differences in the degree of modifiable risk for heart failure in this age group.

GISSI-AF: ARB fails to prevent AF recurrence Posted: 15 Apr 2009 05:00 PM PDT Treatment with the angiotensin receptor blocker valsartan does not reduce the incidence of recurrent atrial fibrillation, findings of the GISSI-AF trial reveal.

Circulating DNA linked to CTCs in breast cancer Posted: 15 Apr 2009 05:00 PM PDT In breast cancer patients, high levels of circulating total/methylated DNA are associated with large numbers of circulating tumor cells, which may point to a more aggressive tumor biology, say Belgian researchers.

Reconstruction delay unnecessary for postmastectomy radiotherapy Posted: 15 Apr 2009 05:00 PM PDT Women who receive radiotherapy after reconstructive surgery do not have a higher rate of major complications than those who delay the cosmetic procedure, US researchers have found.

Prostate cancer detection ‘may be affected by aspirin use’ Posted: 14 Apr 2009 05:00 PM PDT Prostate-specific antigen levels are significantly lower in aspirin users with latent prostate cancerthan in similar patients who are not aspirin users, but there is no link with prostate volume, say US scientists who caution that aspirin may affect prostate cancer detection.

Radical prostatectomy well tolerated after previous prostate surgery Posted: 14 Apr 2009 05:00 PM PDT Radical retropubic prostatectomy can be performed with no difference in pathologic outcomes after previous prostate surgery, despite being technically more difficult the second time around, Turkish study findings indicate.

Genome-wide study indicates genes associated with early breast cancer Posted: 14 Apr 2009 05:00 PM PDT Two regions in the genes GLG1 and UGT1 may be associated with early onset breast cancer, results of a pilot genome-wide association study suggest.

Low-dose-rate brachytherapy outcomes ‘good in low-risk prostate cancer’ Posted: 13 Apr 2009 05:00 PM PDT For men with low- and "low-tier" intermediate-risk prostate cancer, low-dose-rate brachytherapy can produce outcomes at least equal to those with external beam radiotherapy or surgical prostatectomy, say Canadian scientists.

Quantitative multiplexed analysis predicts breast cancer outcome Posted: 13 Apr 2009 05:00 PM PDT Analysis of expression of the ErbB family of receptors by quantitative multiplexing may provide better prediction of prognosis than currently available methods, study results suggest.

IL-7/IL-15 increases immune response, inhibits tumor development, metastases Posted: 13 Apr 2009 05:00 PM PDT Intralesional injection of interleukin-7 and IL-15 enhances the effects of radiofrequency thermal ablation in inhibiting tumor development and metastases, animal study results show.

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