Medical News

Breath test predicts airway damage in asthmatic smokers Posted: 30 Apr 2009 05:00 PM PDT The oxidative airway damage that smoking causes in patients with asthma can be easily assessed by measuring the pH of their breath, UK researchers believe.

Leptin disturbance could explain weight loss in COPD patients Posted: 30 Apr 2009 05:00 PM PDT Acute exacerbations of chronic obstructive pulmonary disease are accompanied by chronic disturbances in levels of leptin and insulin-like growth factor-1, study findings suggest.

Fluticasone nasal spray effective in children Posted: 30 Apr 2009 05:00 PM PDT A fluticasone furoate nasal spray is well tolerated and effective for the treatment of seasonal allergic rhinitis in children, US research shows.

Exposure-based CBT effective for PTSD in schizophrenia patients Posted: 30 Apr 2009 05:00 PM PDT Exposure-based cognitive behavioral therapy may be effective for treating post-traumatic stress disorder in patients with schizophrenia or schizoaffective disorder, results of a pilot study suggest.

Obesity rates high among bipolar patients in developing countries Posted: 30 Apr 2009 05:00 PM PDT People with bipolar disorder in Brazil are more likely to be obese than the general population, say researchers in findings that emphasize the importance of early detection and treatment of obesity and the metabolic syndrome among such patients in developing countries.

Call for earlier use of systemic treatments in moderate-to-severe psoriasis Posted: 30 Apr 2009 05:00 PM PDT French researchers have raised concerns that systemic treatments are often used too late in patients with moderate-to-severe psoriasis.

Topical corticosteroids remain the short-term option for scalp psoriasis Posted: 30 Apr 2009 05:00 PM PDT Topical corticosteroids are the recommended short-term or intermittent treatment for scalp psoriasis, concludes The National Psoriasis Foundation Medical Board.

MMP-2 promoter shows variability in specific subgroup of psoriasis patients Posted: 30 Apr 2009 05:00 PM PDT The matrix metalloproteinase -2 promoter is a gene modulator of psoriasis in specific subgroups of psoriasis patients, research shows.

Psoriasis patients have trace element disturbance Posted: 30 Apr 2009 05:00 PM PDT Researchers have identified a disturbance in trace element concentrations in patients with psoriasis that results in an elemental homeostatic imbalance.

Prednisolone attenuates rocuronium-induced neuromuscular blockade Posted: 30 Apr 2009 05:00 PM PDT Daily medication with the glucocorticoid prednisolone attenuates the neuromuscular blockade effect of rocuronium, a study of patients with inflammatory bowel disease has shown.

Novel index rates recovery after ambulatory surgery and anesthesia Posted: 30 Apr 2009 05:00 PM PDT Researchers have developed a novel assessment tool, called the Functional Recovery Index, to gauge the recovery of patients after ambulatory surgery and anesthesia.

Intra-operative colloid volume affects primary graft dysfunction risk Posted: 30 Apr 2009 05:00 PM PDT Increasing intra-operative colloid volume is independently associated with increased primary graft dysfunction, say researchers.

Value of pre-operative anesthesia consultation in dispute Posted: 30 Apr 2009 05:00 PM PDT Pre-operative anesthesia consultation reduces the time that surgical patients remain in hospital, but does not improve their survival, a population-based study indicates.

Impossible mask ventilation rare in practice Posted: 30 Apr 2009 05:00 PM PDT Patients who cannot be ventilated with a mask are encountered rarely in clinical practice, but these patients are often also difficult to intubate, US research shows.

Talk therapy may benefit schizophrenia patients with stress disorder Posted: 29 Apr 2009 05:00 PM PDT Patients with schizophrenia who suffer from post-traumatic stress disorder may benefit from type of talk therapy called exposure-based cognitive behavioral therapy, results of a pilot study suggest.

Acute stroke units in UK ‘still underused’ Posted: 29 Apr 2009 05:00 PM PDT Acute stroke care continues to improve across England, Wales, and Northern Ireland, but acute stroke units remain significantly underused, with around a quarter of stroke patients still not receiving the best treatment, an audit by the Royal College of Physicians shows.

Brief and simple intervention can improve breast self-examination technique Posted: 29 Apr 2009 05:00 PM PDT A simple intervention programme consisting of one counselling session and two follow-up phone calls can significantly improve breast self-examination technique, US research suggests.

Folic acid may help reduce asthma and allergy symptoms Posted: 29 Apr 2009 05:00 PM PDT Folic acid may help suppress allergic reactions and reduce the severity of allergy and asthma symptoms, results of a US study suggest.

Abdominal obesity raises VTE risk Posted: 29 Apr 2009 05:00 PM PDT Abdominal obesity is a key risk factor for venous thromboembolism, demonstrate the findings from two studies published in the Journal of Thrombosis and Haemostasis.

Thrombolysis benefits young adults with ischemic stroke Posted: 29 Apr 2009 05:00 PM PDT Young adults who receive thrombolysis for acute ischemic stroke have a better clinical outcome than non-thrombolyzed patients of the same age, Finnish researchers report

Clinical factors predicting unilateral prostate cancer revealed Posted: 29 Apr 2009 05:00 PM PDT A negative family history of prostate cancer and unilaterality on prostate biopsy are significant predictors for unilateral disease on pathologic analysis, say US scientists in findings that may aid in the selection of patients for hemiablation.

<i>TOP2A</i> mutations predict breast cancer anthracycline response Posted: 29 Apr 2009 05:00 PM PDT Women whose breast tumors have alterations in the topoisomerase II alpha gene are more likely to respond to anthracycline treatment than those without such mutations, study findings indicate.

Weight control, activity breast cancer trials proposed Posted: 29 Apr 2009 05:00 PM PDT Randomized clinical trials should be conducted to clarify the impact of physical activity and body weight on the risk for postmenopausal breast cancer, recommend researchers.

Clinical factors predicting unilateral prostate cancer revealed Posted: 29 Apr 2009 05:00 PM PDT A negative family history of prostate cancer and unilaterality on prostate biopsy are significant predictors for unilateral disease on pathologic analysis, say US scientists in findings that may aid in the selection of patients for hemiablation.

Low adiponectin linked to thin-cap fibroatheroma in men with CAD Posted: 29 Apr 2009 05:00 PM PDT Men with stable coronary artery disease who also have low levels of adiponectin are more likely to have thin-cap fibroatheroma plaques, suggest Japanese researchers.

Almonds have small beneficial effect on lipids Posted: 29 Apr 2009 05:00 PM PDT Results from a systematic review and meta-analysis of randomized controlled trials show that almond consumption reduces total cholesterol by a small but significant extent, but has nonsignificant effects on other lipids, report researchers.

Diabetes and CVD control improving, but not in all patient groups Posted: 29 Apr 2009 05:00 PM PDT The past decade has seen improvements in blood-pressure, glucose, and cholesterol control in patients with cardiovascular disease and diabetes, but racial, ethnic, and socioeconomic differences persist, according to a study published in the Annals of Internal Medicine.

Androgen deficiency linked to increased CV mortality in Type 2 diabetes Posted: 29 Apr 2009 05:00 PM PDT Androgen deficiencies are common in men with Type 2 diabetes and stable coronary artery disease, and associated with increased cardiovascular mortality, a new study finds.

Sleep apnea predicts death in ischemic HF Posted: 29 Apr 2009 05:00 PM PDT Sleep apnea is associated with increased mortality in patients with ischemic, but not in those with nonischemic, heart failure, show study findings.

Pre-operative homocysteine predicts mortality, especially post CABG Posted: 29 Apr 2009 05:00 PM PDT Preoperative elevated homocysteine is independently associated with an increased risk for perioperative thromboembolic events and mortality in cardiac surgery patients, particularly in patients undergoing coronary artery bypass graft surgery, shows research.

Weight control, activity breast cancer trials proposed Posted: 29 Apr 2009 05:00 PM PDT Randomized clinical trials should be conducted to clarify the impact of physical activity and body weight on the risk for postmenopausal breast cancer, recommend researchers.

<i>TOP2A</i> mutations predict breast cancer anthracycline response Posted: 29 Apr 2009 05:00 PM PDT Women whose breast tumors have alterations in the topoisomerase II alpha gene are more likely to respond to anthracycline treatment than those without such mutations, study findings indicate.

Ejaculatory quality and function reduced after prostate brachytherapy Posted: 28 Apr 2009 05:00 PM PDT The majority of men treated with brachytherapy for prostate cancer have preserved ejaculatory function, but they experience reductions in volumes of ejaculate and a reduced ability to orgasm, French study findings indicate.

<i>IL-10</i> gene variants linked to prostate cancer risk Posted: 28 Apr 2009 05:00 PM PDT Prostate cancer risk is associated with genetic variation in interleukin-10 and, potentially, toll-like receptor 4 genes, say US scientists who found no direct associations with single nucleotide polymorphisms in obesity genes.

Number of axillary nodes removed predicts regional breast cancer recurrence Posted: 28 Apr 2009 05:00 PM PDT The number of axillary nodes removed during axillary node dissection predicts regional recurrence in node-negative breast cancer patients, study results show.

Glycemic control predicts prostate cancer aggressiveness in diabetes Posted: 27 Apr 2009 05:00 PM PDT Diabetes itself is not associated with prostate cancer aggressiveness, but glycemic control predicts an aggressive tumor profile in patients with both prostate cancer and diabetes, say Korean scientists.

Methylene blue dye injection for breast cancer staging causes cutaneous side effects Posted: 27 Apr 2009 05:00 PM PDT In addition to the well-known problem of skin necrosis, methylene blue dye injection leads to more subtle cutaneous adverse effects when used for lymphatic mapping/sentinel lymphadenectomy in staging of breast cancer, show US study findings.

Extensive soft tissue resection for locally recurrent breast cancer produces lasting local control Posted: 27 Apr 2009 05:00 PM PDT Large soft tissue resection followed by autologous tissue closure for local relapse of breast cancer provides local control with acceptable morbidity, Dutch study results show.

Post-prostatectomy disease control improved by radiotherapy Posted: 26 Apr 2009 05:00 PM PDT After radical prostatectomy, postoperative radiotherapy and early referral for salvage radiotherapy improve disease control, while increasing urinary toxicity, conclude Italian scientists.

AR in prostate cancer stroma and normal tissue linked to outcomes Posted: 26 Apr 2009 05:00 PM PDT Androgen receptor levels in both the tumor stroma and the surrounding normal tissue are associated with prostate cancer aggressiveness and the efficacy of castration therapy, Swedish study findings indicate.

DMPA effectiveness unaffected by antiretroviral triple therapy Posted: 26 Apr 2009 05:00 PM PDT The use of combination antiretroviral therapy with zidovudine, lamivudine, and efavirenz by HIV-infected women does not affect the pharmacokinetics of depot medroxyprogesterone acetate, according to US study results.

AMH levels unaffected by weight loss in obese women with PCOS Posted: 26 Apr 2009 05:00 PM PDT A 20-week weight loss intervention improves reproductive function with no impact on anti-Müllerian hormone levels in overweight and obese women with polycystic ovary syndrome, study results suggest.

Chromosome instability occurs frequently in human embryos Posted: 26 Apr 2009 05:00 PM PDT Belgian researchers have found that chromosome instability, a hallmark of tumorigenesis, is common during early human embryogenesis.

Neoadjuvant chemotherapy for breast cancer facilitates axillary-conserving surgery Posted: 26 Apr 2009 05:00 PM PDT Neoadjuvant chemotherapy downstages primary breast cancer and axillary lymph node metastases thereby facilitating both breast- and axillary-conserving surgery, study shows.

Very hot tea may increase esophageal cancer risk Posted: 05 Apr 2009 05:00 PM PDT People have been advised to let hot beverages cool a little before drinking, following a Middle-Eastern study that has linked esophageal cancer with the consumption of very hot tea.

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