Medical News

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• Serial better than cross-shift PEF measurements for occupational asthma diagnosis
• Smoking in pregnancy linked to reduced lung function in offspring
• Diet in pregnancy may influence wheezing risk in children
• Negative symptoms key to schizophrenia neurocognition–function link
• Cardiovascular disease and hypertension risk increased in bipolar I disorder
• Obesity impact on prostate cancer varies with ethnicity
• Prostate cancer screening in the USA may cause overdiagnosis
• Mastectomy rates increasing at Mayo Clinic
• Triglyceride transfer protein polymorphism linked to atherogenic lipid profile
• Lipoprotein (a) ‘pro-atherogenic and pro-thrombotic’
• Nonfasting triglycerides data from Copenhagen receive muted response
• JUPITER analysis shows statin benefits in elderly subgroup
• RBP4 not linked to insulin resistance in Chinese diabetics
• Mediterranean-style diet halves need for antihyperglycemic medication
• Nonfasting triglycerides data from Copenhagen receive muted response
• JUPITER analysis shows statin benefits in elderly subgroup
• BEAUTIFUL subanalyses shed further light on ivabradine’s therapeutic potential
• TRITON-TIMI 38: No need to avoid using PPIs with thienopyridines
• NORDISTEMI: Rapid transfer to cath lab best for STEMI patients in remote areas

Serial better than cross-shift PEF measurements for occupational asthma diagnosis Posted: 02 Sep 2009 05:00 PM PDT Serial measurement of peak expiratory flow is superior to cross-shift measurements of PEF changes for diagnosing occupational asthma, say UK researchers.

Smoking in pregnancy linked to reduced lung function in offspring Posted: 02 Sep 2009 05:00 PM PDT Maternal smoking during pregnancy is associated with poorer lung function among offspring in early adulthood, results of an Australian study show.

Diet in pregnancy may influence wheezing risk in children Posted: 02 Sep 2009 05:00 PM PDT An increased maternal intake of α-linolenic acid and docosahexaenoic acid during pregnancy may protect against wheeze in early childhood, results of a Japanese study suggest.

Negative symptoms key to schizophrenia neurocognition–function link Posted: 02 Sep 2009 05:00 PM PDT Negative symptoms may partly mediate the relationship between neurocognition and functional outcome in schizophrenia, despite also being a predictor of outcome, the results of a study indicate.

Cardiovascular disease and hypertension risk increased in bipolar I disorder Posted: 02 Sep 2009 05:00 PM PDT Adults with bipolar I disorder are at increased risk for cardiovascular disease and hypertension, which occur over a decade earlier than in adults without the disorder, researchers have discovered.

Obesity impact on prostate cancer varies with ethnicity Posted: 01 Sep 2009 05:00 PM PDT Body mass and weight gain in adulthood affects a man's future risk for prostate cancer, according to a study undertaken using a multi-racial cohort.

Prostate cancer screening in the USA may cause overdiagnosis Posted: 01 Sep 2009 05:00 PM PDT The introduction of prostate-specific antigen screening for prostate cancer in the USA has resulted in an estimated 1 million additional men being diagnosed and treated for the disease since 1986 than would otherwise have occurred, US study findings report.

Mastectomy rates increasing at Mayo Clinic Posted: 01 Sep 2009 05:00 PM PDT Mastectomy rates have increased in recent years with both surgery year and magnetic resonance imaging significantly predicting this type of surgery, US researchers report.

Triglyceride transfer protein polymorphism linked to atherogenic lipid profile Posted: 01 Sep 2009 05:00 PM PDT Scientists have identified two polymorphisms in the microsomal triglyceride transfer protein gene that are associated with the development of atherosclerosis and cardiovascular disease.

Lipoprotein (a) ‘pro-atherogenic and pro-thrombotic’ Posted: 01 Sep 2009 05:00 PM PDT A large, retrospective review has confirmed pro-thrombotic and pro-inflammatory roles of lipoprotein (Lp)(a) in coronary events.

Nonfasting triglycerides data from Copenhagen receive muted response Posted: 01 Sep 2009 05:00 PM PDT Data from the Copenhagen City Heart study indicate that nonfasting triglyceride levels better predict mortality than nonfasting cholesterol levels, reported investigators at the European Society of Cardiology annual meeting in Barcelona, Spain.

JUPITER analysis shows statin benefits in elderly subgroup Posted: 01 Sep 2009 05:00 PM PDT Latest findings from the JUPITER trial show that the benefits of rosuvastatin treatment for primary cardiovascular disease prevention among people with normal cholesterol but elevated C-reactive protein levels extend to the elderly.

RBP4 not linked to insulin resistance in Chinese diabetics Posted: 01 Sep 2009 05:00 PM PDT Levels of retinol-binding protein 4 in patients with diabetes are related to some metabolic parameters including uric acid and serum lipids, but not to insulin resistance, researchers report.

Mediterranean-style diet halves need for antihyperglycemic medication Posted: 01 Sep 2009 05:00 PM PDT Overweight diabetic individuals who have not previously received treatment are around half as likely to need antihyperglycemic therapy if they follow a Mediterranean-style diet, rather than a low-fat diet, say researchers.

Nonfasting triglycerides data from Copenhagen receive muted response Posted: 01 Sep 2009 05:00 PM PDT Data from the Copenhagen City Heart study indicate that nonfasting triglyceride levels better predict mortality than nonfasting cholesterol levels, reported investigators at the European Society of Cardiology annual meeting in Barcelona, Spain.

JUPITER analysis shows statin benefits in elderly subgroup Posted: 01 Sep 2009 05:00 PM PDT Latest findings from the JUPITER trial show that the benefits of rosuvastatin treatment for primary cardiovascular disease prevention among people with normal cholesterol but elevated C-reactive protein levels extend to the elderly.

BEAUTIFUL subanalyses shed further light on ivabradine’s therapeutic potential Posted: 01 Sep 2009 05:00 PM PDT Ivabradine can help reduce the incidence of major cardiovascular events in a subgroup of patients with stable coronary artery disease and left ventricular systolic dysfunction who present with "limiting angina," research suggests.

TRITON-TIMI 38: No need to avoid using PPIs with thienopyridines Posted: 01 Sep 2009 05:00 PM PDT The use of proton pump inhibitors does not need to be avoided when using the thienopyridine antiplatelet agents clopidogrel or prasugrel in patients with acute coronary syndromes undergoing percutaneous coronary intervention, research indicates.

NORDISTEMI: Rapid transfer to cath lab best for STEMI patients in remote areas Posted: 01 Sep 2009 05:00 PM PDT Patients with ST-elevation myocardial infarction who live in remote areas fare better with thrombolysis and early angioplasty than with a more conservative strategy, indicate results of a clinical trial.

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