Medical News

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• Early pulmonary rehab recommended in acute COPD
• Procalcitonin predicts mortality in acute COPD
• No evidence for rebound effect of tiotropium withdrawal in COPD
• Right prefrontal repetitive TMS may benefit bipolar mania patients
• Childhood coordination deficits point to later schizophrenia
• Proximal and distal DVT patients differ in mortality risk
• Bilirubin ‘may protect against stroke’
• Confirmatory tumor biopsy may alter metastatic breast cancer management
• Prostate cancer treatment preferences affected by information sources
• Postpartum IUS insertion timing may affect expulsion rates
• Mild glucose intolerance in pregnancy points to later cardiovascular disease
• Iron supplements raise heart and diabetes risks in midpregnancy
• OHC more effective than calcium carbonate in preventing bone loss
• Office-based hysteroscopic sterilization ‘well tolerated’
• Cycle length does not indicate ovulatory status in perimenopausal women
• FDG PET/CT accurately spots pelvic node metastasis in endometrial cancer
• Ovarian cancer symptoms present months before diagnosis
• Total cholesterol reductions fail to track coronary calcium score changes
• ‘Fatostatin’ molecule blocks lipogenic transcription factors
• Pioglitazone and bedtime insulin have similar impact on CV risk factors
• Pioglitazone and bedtime insulin have similar impact on CV risk factors
• Saxagliptin added to metformin improves glycemic control
• Bone marker ratio predicts vertebral fracture in Type 2 diabetes men
• Cardiac tropinin T levels ‘powerfully predictive’ of CABG complications
• Routine ECG screening of athletes supported
• Pre-warmed fluids help prevent hypothermia in cesarean deliveries
• Melatonin eases postoperative emergence delirium in children
• Licorice gargle reduces postoperative sore throat
• Sugammadex effective and well tolerated in cardiac patients

Early pulmonary rehab recommended in acute COPD Posted: 07 Sep 2009 05:00 PM PDT Patients recovering from acute exacerbation of chronic obstructive pulmonary disease should be promptly referred for pulmonary rehabilitation, say researchers, who found the strategy to be both feasible and effective.

Procalcitonin predicts mortality in acute COPD Posted: 07 Sep 2009 05:00 PM PDT The survival of patients admitted to an intensive care unit with acute exacerbation of chronic obstructive pulmonary disease is predicted by the level of plasma procalcitonin, study results show.

No evidence for rebound effect of tiotropium withdrawal in COPD Posted: 07 Sep 2009 05:00 PM PDT Patients with chronic obstructive pulmonary disease who are taken off long-term treatment with tiotropium display deterioration in dyspnea and peak expiratory flow rate 3 weeks after withdrawal, study results demonstrate.

Right prefrontal repetitive TMS may benefit bipolar mania patients Posted: 07 Sep 2009 05:00 PM PDT Bipolar mania patients may benefit from high-frequency, supra-threshold, right prefontal repetitive transcranial magnetic stimulation as an adjunct to pharmacotherapy, the results of an Indian study indicate.

Childhood coordination deficits point to later schizophrenia Posted: 07 Sep 2009 05:00 PM PDT Children who later develop schizophrenia spectrum disorder are significantly more likely to display coordination deficits than children who do not develop a mental illness, researchers have discovered.

Proximal and distal DVT patients differ in mortality risk Posted: 06 Sep 2009 05:00 PM PDT Patients with proximal deep vein thrombosis have a higher risk for death than those with distal clots, show results from the OPTIMEV study.

Bilirubin ‘may protect against stroke’ Posted: 06 Sep 2009 05:00 PM PDT High serum levels of bilirubin are associated with a reduced incidence of ischemic stroke among Korean men, new research reveals.

Confirmatory tumor biopsy may alter metastatic breast cancer management Posted: 06 Sep 2009 05:00 PM PDT Canadian researchers have found substantial discordance in receptor status between primary tumor and suspected metastases in women with breast cancer.

Prostate cancer treatment preferences affected by information sources Posted: 06 Sep 2009 05:00 PM PDT Men with newly-diagnosed localized prostate cancer consult a wide variety of information sources before deciding on their preferred treatment option, research findings suggest.

Postpartum IUS insertion timing may affect expulsion rates Posted: 06 Sep 2009 05:00 PM PDT Although there is no increased risk of complication with insertion of an intrauterine device in the postpartum period, the timing of insertion may have an impact on expulsion rates, conclude US and Swiss researchers.

Mild glucose intolerance in pregnancy points to later cardiovascular disease Posted: 06 Sep 2009 05:00 PM PDT The presence of mild glucose intolerance during pregnancy appears to be associated with an increased risk for cardiovascular disease in later life, Canadian researchers have discovered.

Iron supplements raise heart and diabetes risks in midpregnancy Posted: 06 Sep 2009 05:00 PM PDT Women taking iron supplements in midpregnancy are at raised risk for gestational diabetes mellitus, hypertension, and metabolic syndrome, despite benefits in reducing low birthweight and preterm delivery, say Italian scientists.

OHC more effective than calcium carbonate in preventing bone loss Posted: 06 Sep 2009 05:00 PM PDT Ossein-hydroxyapatite complex is significantly more effective than calcium carbonate in preventing bone loss in patients with or at risk for osteopenia or osteoporosis, conclude Spanish investigators.

Office-based hysteroscopic sterilization ‘well tolerated’ Posted: 06 Sep 2009 05:00 PM PDT Hysteroscopic sterilization performed using local anesthetic in a family practice office is well tolerated and patients express satisfaction with the technique, the results of a US study indicate.

Cycle length does not indicate ovulatory status in perimenopausal women Posted: 06 Sep 2009 05:00 PM PDT Cycle length is not indicative of whether a cycle is ovulatory or not in perimenopausal women, conclude US researchers who say exposure to the risk of conception in women with long cycles is not negligible.

FDG PET/CT accurately spots pelvic node metastasis in endometrial cancer Posted: 06 Sep 2009 05:00 PM PDT Pelvic node metastases in high-risk, early-stage endometrial cancer can be accurately assessed presurgically using 18F-fluorodeoxyglucose positron emission tomography/computed tomography, say Italian scientists.

Ovarian cancer symptoms present months before diagnosis Posted: 06 Sep 2009 05:00 PM PDT Women with ovarian cancer usually have symptoms that they report to primary care often months before receiving a diagnosis, UK researchers have discovered.

Total cholesterol reductions fail to track coronary calcium score changes Posted: 06 Sep 2009 05:00 PM PDT Reductions in total cholesterol levels in response to lipid-lowering treatment are not reflected by coronary calcium score changes in patients with stable coronary artery disease, research indicates.

‘Fatostatin’ molecule blocks lipogenic transcription factors Posted: 06 Sep 2009 05:00 PM PDT A recently discovered small molecule can block key lipogenic transcription factors that govern the homeostasis of fat metabolism, research suggests.

Pioglitazone and bedtime insulin have similar impact on CV risk factors Posted: 06 Sep 2009 05:00 PM PDT Add-on treatment with pioglitazone or bedtime insulin has a similar impact on intra-abdominal fat mass and systemic low-grade inflammation – two well known cardiovascular risk factors – in patients with Type 2 diabetes, research shows.

Pioglitazone and bedtime insulin have similar impact on CV risk factors Posted: 06 Sep 2009 05:00 PM PDT Add-on treatment with pioglitazone or bedtime insulin has a similar impact on intra-abdominal fat mass and systemic low-grade inflammation – two well known cardiovascular risk factors – in patients with Type 2 diabetes, research shows.

Saxagliptin added to metformin improves glycemic control Posted: 06 Sep 2009 05:00 PM PDT A saxagliptin phase III dose-ranging study shows clinically significant reductions in glycated hemoglobin when the drug is added to metformin in patients with Type 2 diabetes inadequately controlled with metformin alone, researchers report in the journal Diabetes Care.

Bone marker ratio predicts vertebral fracture in Type 2 diabetes men Posted: 06 Sep 2009 05:00 PM PDT Research indicates that measuring levels of osteocalcin and bone-specific alkaline phosphatase may help identify men with Type 2 diabetes at risk for vertebral fracture.

Cardiac tropinin T levels ‘powerfully predictive’ of CABG complications Posted: 06 Sep 2009 05:00 PM PDT Marked cardiac troponin T elevation after coronary artery bypass graft surgery is a strong predictor of postoperative cardiovascular complications, say researchers in findings that imply current recommendations for cTnT specifically for diagnosis of post-operative myocardial infarction should be reconsidered.

Routine ECG screening of athletes supported Posted: 06 Sep 2009 05:00 PM PDT Several newly published studies support recommendations for routine testing of young athletes using an electrocardiogram to prevent sudden cardiac deaths triggered by vigorous exercise.

Pre-warmed fluids help prevent hypothermia in cesarean deliveries Posted: 03 Sep 2009 05:00 PM PDT Administering pre-warmed colloid followed by crystalloids before spinal anesthesia to women undergoing cesarean delivery may help to maintain their core temperature and improve neonatal outcomes, researchers have found.

Melatonin eases postoperative emergence delirium in children Posted: 03 Sep 2009 05:00 PM PDT Taking oral melatonin before surgery could help reduce emergence delirium in children undergoing anesthesia and surgery, a US team report.

Licorice gargle reduces postoperative sore throat Posted: 03 Sep 2009 05:00 PM PDT Gargling with a licorice solution before anesthesia could help reduce postoperative sore throat, study findings reveal.

Sugammadex effective and well tolerated in cardiac patients Posted: 03 Sep 2009 05:00 PM PDT Sugammadex, a novel relaxant binding agent, has demonstrated preliminary safety and efficacy for the reversal of recoruonium-induced neuromuscular blockade in cardiac patients.

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