Medical News

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• ICS treatment may reduce bronchial vascular remodeling in COPD
• Bacterial and viral co-infection does not increase exacerbation severity in COPD
• Metabolic syndrome common in Taiwanese schizophrenia patients
• Auditory P300 amplitude ‘marker for general psychosis’
• Antibiotic prophylaxis reduces infection but not mortality in acute stroke
• ECMO best for severe acute respiratory failure
• Active smoking increases risk for asthma symptoms in adolescents
• Regular inhaled glucocorticoids best for infant wheeze
• Schizophrenia risk increased by increasing paternal age
• Elderly bipolar disorder patients show ‘typical cognitive deficit profile’
• Prostate cancer detection equally successful with 8- or 12-core biopsy
• Prostate cancer detection equally successful with 8- or 12-core biopsy
• Physical problems stressful during breast canceradjuvant chemotherapy
• GP surveillance and intervention fail to impact childhood obesity
• Adiponectin may be early biomarker for cardiometabolic risk
• Atherogenic Lyso-C LDL component increased with oxidative stress
• Cinnamon reduces HbA1c in Type 2 diabetics
• Less than 10% of Americans have low-risk CVD profile
• Alcohol, drug use can precipitate atrial fibrillation in young adults
• Physical problems stressful during breast canceradjuvant chemotherapy
• Ethnic origin affects prostate cancer surgery outcome
• Conservative management of localized prostate cancer has improved
• Ethnic origin affects prostate cancer surgery outcome
• Conservative management of localized prostate cancer has improved
• Risks and benefits of prophylactic breast cancer treatment reviewed
• Only small number of Dutch FH patients reach LDL cholesterol targets
• Variation in <i>NPC1L1</i> is associated with lipid levels and CHD risk
• LANCET finds no anti-inflammatory effects with insulin, metformin therapy
• Real-world data confirm exenatide efficacy for Type 2 diabetes
• Benefits of IMA in CABG surgery not reaching all patients
• Black patients less likely to survive in-hospital cardiac arrest than Whites
• Risks and benefits of prophylactic breast cancer treatment reviewed
• Common sexually transmitted infection linked to aggressive prostate cancer
• Information on use of breast cancer targeted testing is lacking
• Prostate cancer risk appreciable even after two negative biopsies
• Prostate cancer detection and aggressiveness raised in smaller prostates
• Securin immunopositivity predicts poor breast cancer outcome

ICS treatment may reduce bronchial vascular remodeling in COPD Posted: 17 Sep 2009 05:00 PM PDT Bronchial vascular remodeling in patients with chronic obstructive pulmonary disease is mainly caused by morphologic changes in mucosal microvessels rather than new vessel formation, which may be reduced with inhaled corticosteroids, researchers have found.

Bacterial and viral co-infection does not increase exacerbation severity in COPD Posted: 17 Sep 2009 05:00 PM PDT Viruses are frequent causes of acute exacerbations in patients with chronic obstructive pulmonary disease, but co-infection with bacteria does not appear to increase the severity of such attacks, researchers have found.

Metabolic syndrome common in Taiwanese schizophrenia patients Posted: 17 Sep 2009 05:00 PM PDT Taiwanese patients with schizophrenia and schizoaffective disorder have a high prevalence of the metabolic syndrome that becomes apparent early on in their lives, say researchers who identified risk factors associated with the syndrome.

Auditory P300 amplitude ‘marker for general psychosis’ Posted: 17 Sep 2009 05:00 PM PDT The auditory event-related P300 amplitude appears to be an endophenotype for schizophrenia, but it is also affected in bipolar disorder patients and may be a marker for psychosis in general, conclude UK researchers.

Antibiotic prophylaxis reduces infection but not mortality in acute stroke Posted: 16 Sep 2009 05:00 PM PDT Prophylactic antibiotic therapy in patients with acute stroke reduces the risk for infection but has no impact on mortality, results from a systematic review and meta-analysis indicate.

ECMO best for severe acute respiratory failure Posted: 16 Sep 2009 05:00 PM PDT Extracorporeal membrane oxygenation is better than conventional ventilator management for improving the chances of survival without disability among patients with severe acute respiratory failure, say UK researchers.

Active smoking increases risk for asthma symptoms in adolescents Posted: 16 Sep 2009 05:00 PM PDT Smoking significantly increases the risk for asthma symptoms and reduced lung function in adolescents, Korean study results show.

Regular inhaled glucocorticoids best for infant wheeze Posted: 16 Sep 2009 05:00 PM PDT Regular treatment with inhaled glucocorticoids is more effective for frequent wheeze than "as needed" treatment is preschool children, research shows.

Schizophrenia risk increased by increasing paternal age Posted: 16 Sep 2009 05:00 PM PDT The risk of schizophrenia appears to be increased in the offspring of fathers aged 55 years and above, potentially due to chromosomal aberrations and mutations of the aging germline, argue US researchers.

Elderly bipolar disorder patients show ‘typical cognitive deficit profile’ Posted: 16 Sep 2009 05:00 PM PDT Older bipolar disorder patients have a similar cognitive profile to that of younger patients with the disease, say Swiss scientists, who suggest that processing speed and episodic memory are two core deficits in elderly patients.

Prostate cancer detection equally successful with 8- or 12-core biopsy Posted: 16 Sep 2009 05:00 PM PDT Prostate cancer detection rates achieved using either 8- or 12-core biopsy protocols are the same, according to Dutch researchers who compared the two methods.

Prostate cancer detection equally successful with 8- or 12-core biopsy Posted: 16 Sep 2009 05:00 PM PDT Prostate cancer detection rates achieved using either 8- or 12-core biopsy protocols are the same, according to Dutch researchers who compared the two methods.

Physical problems stressful during breast canceradjuvant chemotherapy Posted: 16 Sep 2009 05:00 PM PDT Physical symptoms are reported three times more often than psychosocial problems as the most stressful daily event experienced by women undergoing adjuvant chemotherapy for breast cancer, a Swedish study shows.

GP surveillance and intervention fail to impact childhood obesity Posted: 16 Sep 2009 05:00 PM PDT Assessing and treating young children for obesity in primary care has no impact on body mass index, physical activity, or nutrition, a randomized controlled trial has found.

Adiponectin may be early biomarker for cardiometabolic risk Posted: 16 Sep 2009 05:00 PM PDT Blood levels of the hormones adiponectin and leptin in children are inversely associated with cardiometabolic risk, Danish researchers have shown.

Atherogenic Lyso-C LDL component increased with oxidative stress Posted: 16 Sep 2009 05:00 PM PDT Lysophosphatidylcholine, a major phospholipid component of atherogenic lipoproteins, is increased in patients with Type 2 diabetes, researchers report.

Cinnamon reduces HbA1c in Type 2 diabetics Posted: 16 Sep 2009 05:00 PM PDT Results from a randomized trial in individuals with Type 2 diabetes show that cinnamon dietary supplementation significantly reduces glycated hemoglobin compared with usual care.

Less than 10% of Americans have low-risk CVD profile Posted: 16 Sep 2009 05:00 PM PDT Less than 10% of US adults had a low cardiovascular disease risk profile during the period 1999 to 2004, a study reveals.

Alcohol, drug use can precipitate atrial fibrillation in young adults Posted: 16 Sep 2009 05:00 PM PDT Alcohol and illicit drug use can precipitate atrial fibrillation in young people, say researchers who call for better guidance on how best to treat such patients.

Physical problems stressful during breast canceradjuvant chemotherapy Posted: 16 Sep 2009 05:00 PM PDT Physical symptoms are reported three times more often than psychosocial problems as the most stressful daily event experienced by women undergoing adjuvant chemotherapy for breast cancer, a Swedish study shows.

Ethnic origin affects prostate cancer surgery outcome Posted: 15 Sep 2009 05:00 PM PDT Prostate cancer patients of African–American origin are more likely to have positive surgical margins at the apex of the prostate after radical prostatectomy than their Caucasian counterparts, US researchers suggest.

Conservative management of localized prostate cancer has improved Posted: 15 Sep 2009 05:00 PM PDT Outcomes for prostate cancer patients treated with conservative management were better for men diagnosed between 1992 and 2002 compared with those diagnosed in the 1970s and 1980s, according to US research findings.

Ethnic origin affects prostate cancer surgery outcome Posted: 15 Sep 2009 05:00 PM PDT Prostate cancer patients of African–American origin are more likely to have positive surgical margins at the apex of the prostate after radical prostatectomy than their Caucasian counterparts, US researchers suggest.

Conservative management of localized prostate cancer has improved Posted: 15 Sep 2009 05:00 PM PDT Outcomes for prostate cancer patients treated with conservative management were better for men diagnosed between 1992 and 2002 compared with those diagnosed in the 1970s and 1980s, according to US research findings.

Risks and benefits of prophylactic breast cancer treatment reviewed Posted: 15 Sep 2009 05:00 PM PDT Tamoxifen, raloxifene, and tibolone each reduce the risk for primary breast cancer compared with placebo, but are associated with increased risks for thromboembolic events, endometrial cancer, or stroke study findings indicate.

Only small number of Dutch FH patients reach LDL cholesterol targets Posted: 15 Sep 2009 05:00 PM PDT Only a small percentage of patients with heterozygous familial hypercholesterolemia achieve target levels of low-density lipoprotein cholesterol, show results from a Dutch study.

Variation in <i>NPC1L1</i> is associated with lipid levels and CHD risk Posted: 15 Sep 2009 05:00 PM PDT Variation in the gene encoding the Niemann–Pick C1-like 1 protein influences levels of low-density lipoprotein cholesterol, as well as risk for coronary heart disease, show results from the PROSPER study.

LANCET finds no anti-inflammatory effects with insulin, metformin therapy Posted: 15 Sep 2009 05:00 PM PDT Individuals with recent onset Type 2 diabetes treated with metformin or insulin do not have significant reductions in inflammatory biomarker levels compared with those treated with placebo, show results from the LANCET trial.

Real-world data confirm exenatide efficacy for Type 2 diabetes Posted: 15 Sep 2009 05:00 PM PDT Results of a "real-world," observational study indicate that exenatide treatment is associated with similar reductions in glycated hemoglobin, weight, blood pressure, and lipids to those achieved with the drug in registration clinical trials.

Benefits of IMA in CABG surgery not reaching all patients Posted: 15 Sep 2009 05:00 PM PDT The frequency of internal mammary artery use in coronary artery bypass graft surgery is increasing, but study findings show that many patients still do not receive the benefits of these grafts.

Black patients less likely to survive in-hospital cardiac arrest than Whites Posted: 15 Sep 2009 05:00 PM PDT Black patients are significantly less likely to survive in-hospital cardiac arrest than are White patients, with lower rates of survival during both the immediate resuscitation and postresuscitation periods, a US study has shown.

Risks and benefits of prophylactic breast cancer treatment reviewed Posted: 15 Sep 2009 05:00 PM PDT Tamoxifen, raloxifene, and tibolone each reduce the risk for primary breast cancer compared with placebo, but are associated with increased risks for thromboembolic events, endometrial cancer, or stroke study findings indicate.

Common sexually transmitted infection linked to aggressive prostate cancer Posted: 14 Sep 2009 05:00 PM PDT The presence of antibodies against the common sexually transmitted infection Trichomonas vaginalis, is associated with the risk for aggressive prostate cancer, US study findings show.

Information on use of breast cancer targeted testing is lacking Posted: 14 Sep 2009 05:00 PM PDT A review carried out by US scientists reveals that there is little information about the use of human epidermal growth factor receptor 2 testing in routine clinical practice, which could provide insight into the evidence needed for testing emerging technologies.

Prostate cancer risk appreciable even after two negative biopsies Posted: 13 Sep 2009 05:00 PM PDT Approximately a quarter of patients with at least two sets of negative prostate biopsies remain at increased risk for prostate cancer, and the majority of tumors detected are clinically significant, the results of a French study indicate.

Prostate cancer detection and aggressiveness raised in smaller prostates Posted: 13 Sep 2009 05:00 PM PDT Men with small prostate volumes and high initial prostate-specific antigen levels have a greater risk for cancer detection and aggressive disease than other men, Dutch researchers have discovered.

Securin immunopositivity predicts poor breast cancer outcome Posted: 13 Sep 2009 05:00 PM PDT Securin immunopositivity is an independent prognostic indicator for invasive breast cancer, Finnish research suggests.

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